Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ruby Pan"'
Autor:
Lawrence J. Dooling, Jason C. Andrechak, Brandon H. Hayes, Siddhant Kadu, William Zhang, Ruby Pan, Manasvita Vashisth, Jerome Irianto, Cory M. Alvey, Leyuan Ma, Dennis E. Discher
Publikováno v:
Nature Biomedical Engineering.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d9fa43c688748d859e1916dcca7c2d
https://doi.org/10.1038/s41551-023-01031-3
https://doi.org/10.1038/s41551-023-01031-3
Autor:
Janith A. Seneviratne, Daenikka Ravindrarajah, Daniel R. Carter, Vicki Zhai, Amit Lalwani, Sukriti Krishan, Anushree Balachandran, Ernest Ng, Ruby Pandher, Matthew Wong, Tracy L. Nero, Shudong Wang, Murray D. Norris, Michelle Haber, Tao Liu, Michael W. Parker, Belamy B. Cheung, Glenn M. Marshall
Publikováno v:
Cancer Medicine, Vol 13, Iss 21, Pp n/a-n/a (2024)
Abstract Background The child cancer, neuroblastoma (NB), is characterised by a low incidence of mutations and strong oncogenic embryonal driver signals. Many new targeted epigenetic modifier drugs have failed in human trials as monotherapy. Methods
Externí odkaz:
https://doaj.org/article/eb0bf02a0c794095a605600e20b3847f
Autor:
Jason C. Andrechak, Lawrence J. Dooling, Brandon H. Hayes, Siddhant Kadu, William Zhang, Ruby Pan, Manasvita Vashisth, Jerome Irianto, Cory M. Alvey, Dennis E. Discher
Macrophages are abundant in solid tumours and typically associate with poor prognosis, but macrophage clusters in tumour nests have also been reported as beneficial even though dispersed macrophages would have more contacts with cancer cells. Here, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::816ec9103ef5e4aba8b07718b004bcf9
https://doi.org/10.1101/2022.01.01.474150
https://doi.org/10.1101/2022.01.01.474150
Autor:
Ifra Tariq, Adeela Yasmin, Ali Imran, Hassnain Akhtar, Muhammad Afzaal, Muhammad Azeem, Ruby Pant, Junaid Abid, Fakhar Islam, Tahir Zahoor, Abdela Befa Kinki
Publikováno v:
International Journal of Food Properties, Vol 26, Iss 1, Pp 2493-2508 (2023)
ABSTRACTMoringa oleifera Lam. (Moringa) plant, which belongs to the Moringaceae family, is an important crop in Asia and Africa. Moringa has been investigated for its health benefits, which are related to several bioactive components found in the pla
Externí odkaz:
https://doaj.org/article/70d33c364a564875abd5979a9f42eb85
Autor:
Jason C. Andrechak, Dennis E. Discher, Ruby Pan, Manasvita Vashisth, Lawrence J. Dooling, Siddhant Kadu, Michael P. Tobin, Brandon H. Hayes
Publikováno v:
Biophysical Journal. 120:89a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b1d0fe10dbe84ae59a1882290df8264
https://doi.org/10.1016/j.bpj.2020.11.743
https://doi.org/10.1016/j.bpj.2020.11.743
Autor:
Manisha Yadav, Ruby Panwar, Anjana Rustagi, Amrita Chakraborty, Amit Roy, Indrakant K. Singh, Archana Singh
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Plants being sessile organisms and lacking both circulating phagocytic cells and somatic adaptive immune response, have thrived on various defense mechanisms to fend off insect pests and invasion of pathogens. CYP450s are the versatile enzymes, which
Externí odkaz:
https://doaj.org/article/ea0c0ca12e5144f0bef0b67abf2669da
The calcium connection: exploring the intricacies of calcium signaling in plant-microbe interactions
Autor:
Neelam Prabha Negi, Geeta Prakash, Parul Narwal, Ruby Panwar, Deepak Kumar, Bharti Chaudhry, Anjana Rustagi
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
The process of plant immune response is orchestrated by intracellular signaling molecules. Since plants are devoid of a humoral system, they develop extensive mechanism of pathogen recognition, signal perception, and intricate cell signaling for thei
Externí odkaz:
https://doaj.org/article/c2a694cca629416bbacc8b61a1d0cedd
Autor:
Sandra Cantilena, Luca Gasparoli, Deepali Pal, Olaf Heidenreich, Jan‐Henning Klusmann, Joost H. A. Martens, Alexandre Faille, Alan J. Warren, Mawar Karsa, Ruby Pandher, Klaartje Somers, Owen Williams, Jasper de Boer
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 6, Pp n/a-n/a (2022)
Abstract Background Improving the poor prognosis of infant leukaemias remains an unmet clinical need. This disease is a prototypical fusion oncoprotein‐driven paediatric cancer, with MLL (KMT2A)‐fusions present in most cases. Direct targeting of
Externí odkaz:
https://doaj.org/article/1c1567bc09014df8bcc740417102afeb
Autor:
Aaminah Khan, Laura D. Gamble, Dannielle H. Upton, Caitlin Ung, Denise M. T. Yu, Anahid Ehteda, Ruby Pandher, Chelsea Mayoh, Steven Hébert, Nada Jabado, Claudia L. Kleinman, Mark R. Burns, Murray D. Norris, Michelle Haber, Maria Tsoli, David S. Ziegler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Diffuse intrinsic pontine glioma (DIPG) is an almost incurable malignant childhood brain tumor. Here, the authors show that the polyamine synthetic pathway is activated in DIPG and that the dual targeting of polyamine synthesis and uptake results in
Externí odkaz:
https://doaj.org/article/4116e5b63fd745dd8d4fa955d44571c8
Autor:
Anahid Ehteda, Sandy Simon, Laura Franshaw, Federico M. Giorgi, Jie Liu, Swapna Joshi, Jourdin R.C. Rouaen, Chi Nam Ignatius Pang, Ruby Pandher, Chelsea Mayoh, Yujie Tang, Aaminah Khan, Caitlin Ung, Ornella Tolhurst, Anne Kankean, Elisha Hayden, Rebecca Lehmann, Sylvie Shen, Anjana Gopalakrishnan, Peter Trebilcock, Katerina Gurova, Andrei V. Gudkov, Murray D. Norris, Michelle Haber, Orazio Vittorio, Maria Tsoli, David S. Ziegler
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108994- (2021)
Summary: Diffuse intrinsic pontine glioma (DIPG) is an aggressive and incurable childhood brain tumor for which new treatments are needed. CBL0137 is an anti-cancer compound developed from quinacrine that targets facilitates chromatin transcription (
Externí odkaz:
https://doaj.org/article/f3c43c1ed6e44cbd8f4c250a0e00921a