Výsledky vyhledávání - "Ruby M. Stewart"

Lysosome-Associated Membrane Proteins h-LAMP1 (CD107a) and h-LAMP2 (CD107b) Are Activation-Dependent Cell Surface Glycoproteins in Human Peripheral Blood Mononuclear Cells Which Mediate Cell Adhesion to Vascular Endothelium

Autor: Minoru Fukuda, Kenneth W. Betzing, Walter Bounds, Sven R. Carlsson, Randall F. Holcombe, Krishnaswamy Kannan, Ruby M. Stewart

Publikováno v: Cellular Immunology. 171:10-19

Lysosome-associated membrane proteins (LAMPs) are transmembrane lysosomal glycoproteins which are detectable at the cell surface of lymphocytes in patients with scleroderma and systemic lupus erythematosus. While these proteins have been shown to med

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce2e20f57c91f9d27036b092bf26e24
https://doi.org/10.1006/cimm.1996.0167

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Alteration in lymphocyte phenotype associated with administration of adjuvant levamisole and 5-fluorouracil

Autor: Ruby M. Stewart, Kenneth W. Betzing, Krishnaswamy Kannan, Randall F. Holcombe

Publikováno v: Cancer Immunology Immunotherapy. 38:394-398

Levamisole (LMS) and 5-fluorouracil (5FU) administered adjuvantly are effective in reducing the relapse rate following surgical resection of Duke's stage C colon carcinoma. It has been postulated that LMS acts to stimulate the immune system and that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b01e45440ec8f32535e28a6cee2cc65
https://doi.org/10.1007/bf01517209

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Social Drinking and the Immune Response: Impairment of Lymphokine-Activated Killer Activity

Autor: Kenneth W. Betzing, Ruby M. Stewart, Randall F. Holcombe, Walter Bounds

Publikováno v: The American Journal of the Medical Sciences. 307:391-395

The effect of limited and intermittent alcohol ingestion on the immune response in humans has not been extensively studied. The authors, in this study, evaluate peripheral blood mononuclear cell cytotoxicity before and after alcohol ingestion in a se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcc82ed11a2b6cc62a2b07093206338
https://doi.org/10.1097/00000441-199406000-00001

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Association of immune parameters with clinical outcome in stage III colon cancer: results of Southwest Oncology Group Protocol 9009

Autor: Ruby M. Stewart, Kenneth S. Betzing, Shaker R. Dakhil, Joth Jacobson, Krishna Kannan, Randall F. Holcombe, John S. Macdonald

Publikováno v: Cancer immunology, immunotherapy : CII. 48(9)

Levamisole (LMS), utilized in the adjuvant treatment of patients with stage III colon cancer, is immunomodulatory. To determine whether alterations in immune parameters before, during and after 12 months of 5FU/LMS therapy correlate with disease-free

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f4d596c245830a0d56fe37397bf6dd
https://pubmed.ncbi.nlm.nih.gov/10602891

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Correlation of serum interleukin-8 and cell surface lysosome-associated membrane protein expression with clinical disease activity in systemic lupus erythematosus

Autor: Robert E. Wolf, Ruby M. Stewart, Kenneth W. Betzing, Vicky C. Hall, Bruce A. Baethge, Minoru Fukuda, Randall F. Holcombe

Publikováno v: Lupus. 3(2)

Cell surface expression of lysosome-associated membrane proteins (LAMPs) correlates with serum interleukin-8 (IL-8) levels, shorter disease duration, greater functional impairment from disease-related symptoms and soluble IL-2 receptor levels (sIL-2R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eec6111fcc4e9d5d8cbfd01420c56e2
https://pubmed.ncbi.nlm.nih.gov/7920621

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Cell surface expression of lysosome-associated membrane proteins (LAMPs) in scleroderma: relationship of lamp2 to disease duration, anti-Sc170 antibodies, serum interleukin-8, and soluble interleukin-2 receptor levels

Autor: Randall F. Holcombe, Bruce A. Baethge, Minoru Fukuda, Kenneth S. Betzing, Ruby M. Stewart, Vicky C. Hall, Robert E. Wolf

Publikováno v: Clinical immunology and immunopathology. 67(1)

Lysosome-associated membrane proteins (LAMPs) are integral transmembrane proteins densely expressed on lysosomes which can be shuttled to the plasma membrane during cell activation. The objective of this study was to examine the expression of LAMPs o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abfe7b8b0b6303d9ac78c2ea972acbb
https://pubmed.ncbi.nlm.nih.gov/8443983

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Chediak-Higashi lymphoblastoid cell lines: granule characteristics and expression of lysosome-associated membrane proteins

Autor: Minoru Fukuda, Ruby M. Stewart, Marjorie Fowler, Kimberly L. Jones, Randall F. Holcombe

Publikováno v: Clinical immunology and immunopathology. 65(3)

Chediak-Higashi syndrome (CHS) is characterized morphologically by the presence of giant lysosomal granules resulting from the dysregulated fusion of primary lysosomes. Lysosome-associated membrane proteins comprise a family of highly glycosylated pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4acf847ee53fe53728f942c97e1876ae
https://pubmed.ncbi.nlm.nih.gov/1333377

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Linkage of loci associated with two pigment mutations on mouse chromosome 13

Autor: Alfred Zweidler, Randall F. Holcombe, Dennis A. Stephenson, Verne M. Chapman, Jonathan G. Seidman, Ruby M. Stewart

Publikováno v: Genetical research. 58(1)

SummaryProgeny from one intra- and two inter-specific backcrosses between divergent strains of mice were typed to map multiple markers in relation to two pigment mutations on mouse chromosome 13, beige (bg) and pearl (pe). Both recessive mutants on a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef4b5ec60cbff724bf8ec82ce56908a
https://pubmed.ncbi.nlm.nih.gov/1682216

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