Response to correspondence on 'Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation'

Autor: Channabasavaiah B. Gurumurthy, Aidan R. O’Brien, Rolen M. Quadros, John Adams, Pilar Alcaide, Shinya Ayabe, Johnathan Ballard, Surinder K. Batra, Marie-Claude Beauchamp, Kathleen A. Becker, Guillaume Bernas, David Brough, Francisco Carrillo-Salinas, Wesley Chan, Hanying Chen, Ruby Dawson, Victoria DeMambro, Jinke D’Hont, Katharine Dibb, James D. Eudy, Lin Gan, Jing Gao, Amy Gonzales, Anyonya Guntur, Huiping Guo, Donald W. Harms, Anne Harrington, Kathryn E. Hentges, Neil Humphreys, Shiho Imai, Hideshi Ishii, Mizuho Iwama, Eric Jonasch, Michelle Karolak, Bernard Keavney, Nay-Chi Khin, Masamitsu Konno, Yuko Kotani, Yayoi Kunihiro, Imayavaramban Lakshmanan, Catherine Larochelle, Catherine B. Lawrence, Lin Li, Volkhard Lindner, Xian-De Liu, Gloria Lopez-Castejon, Andrew Loudon, Jenna Lowe, Loydie Jerome-Majeweska, Taiji Matsusaka, Hiromi Miura, Yoshiki Miyasaka, Benjamin Morpurgo, Katherine Motyl, Yo-ichi Nabeshima, Koji Nakade, Toshiaki Nakashiba, Kenichi Nakashima, Yuichi Obata, Sanae Ogiwara, Mariette Ouellet, Leif Oxburgh, Sandra Piltz, Ilka Pinz, Moorthy P. Ponnusamy, David Ray, Ronald J. Redder, Clifford J. Rosen, Nikki Ross, Mark T. Ruhe, Larisa Ryzhova, Ane M. Salvador, Sabrina Shameen Alam, Radislav Sedlacek, Karan Sharma, Chad Smith, Katrien Staes, Lora Starrs, Fumihiro Sugiyama, Satoru Takahashi, Tomohiro Tanaka, Andrew Trafford, Yoshihiro Uno, Leen Vanhoutte, Frederique Vanrockeghem, Brandon J. Willis, Christian S. Wright, Yuko Yamauchi, Xin Yi, Kazuto Yoshimi, Xuesong Zhang, Yu Zhang, Masato Ohtsuka, Satyabrata Das, Daniel J. Garry, Tino Hochepied, Paul Thomas, Jan Parker-Thornburg, Antony D. Adamson, Atsushi Yoshiki, Jean-Francois Schmouth, Andrei Golovko, William R. Thompson, K. C. Kent Lloyd, Joshua A. Wood, Mitra Cowan, Tomoji Mashimo, Seiya Mizuno, Hao Zhu, Petr Kasparek, Lucy Liaw, Joseph M. Miano, Gaetan Burgio

Publikováno v: Genome Biology, Vol 22, Iss 1, Pp 1-4 (2021)

Externí odkaz: https://doaj.org/article/54d8d756b504456cad4fadda12ce0a6b

The Nestin neural enhancer is essential for normal levels of endogenous Nestin in neuroprogenitors but is not required for embryo development

Autor: Ella Thomson, Ruby Dawson, Chee Ho H’ng, Fatwa Adikusuma, Sandra Piltz, Paul Q. Thomas

Publikováno v: PLoS ONE, Vol 16, Iss 11 (2021)

Enhancers are vitally important during embryonic development to control the spatial and temporal expression of genes. Recently, large scale genome projects have identified a vast number of putative developmental regulatory elements. However, the prop

Externí odkaz: https://doaj.org/article/30456a6e72dd44a8aa48b2c78277475b

Response to correspondence on 'Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation'

Autor: Radislav Sedlacek, Nay Chi Khin, Yo-ichi Nabeshima, Ruby Dawson, Andrew W. Trafford, Paul Q. Thomas, Mizuho Iwama, Gaetan Burgio, Tomoji Mashimo, Neil E. Humphreys, Anne Harrington, Xuesong Zhang, John H. Adams, E. Jonasch, Benjamin Morpurgo, Mariette Ouellet, James D. Eudy, Leen Vanhoutte, David W. Ray, Bernard Keavney, Kenichi Nakashima, Pilar Alcaide, Shiho Imai, Masato Ohtsuka, Tomohiro Tanaka, Xin Yi, Petr Kasparek, Ane M. Salvador, Nikki Ross, Moorthy P. Ponnusamy, Victoria E. DeMambro, Yoshiki Miyasaka, Ilka Pinz, Koji Nakade, Leif Oxburgh, Lin Li, Jenna Lowe, Frederique Vanrockeghem, Katherine J. Motyl, Tino Hochepied, Clifford J. Rosen, Jan Parker-Thornburg, Guillaume Bernas, Christian S. Wright, Lucy Liaw, Huiping Guo, Amy Gonzales, Yuichi Obata, Kathleen A. Becker, Antony Adamson, Channabasavaiah B. Gurumurthy, David Brough, Satoru Takahashi, Fumihiro Sugiyama, Joseph M. Miano, William R. Thompson, Lin Gan, Hideshi Ishii, Jing Gao, Kevin C K Lloyd, Hao Zhu, Daniel J. Garry, Imayavaramban Lakshmanan, Sandra Piltz, Rolen M. Quadros, Satyabrata Das, Joshua A. Wood, Aidan R. O’Brien, Catherine B. Lawrence, Michelle Karolak, Karan Sharma, Mark T. Ruhe, Sabrina Shameen Alam, Katrien Staes, Lora Starrs, Andrew S. I. Loudon, Yoshihiro Uno, Seiya Mizuno, Mitra Cowan, Taiji Matsusaka, Yuko Yamauchi, Chad Smith, Andrei Golovko, Brandon J. Willis, Larisa Ryzhova, Catherine Larochelle, Hiromi Miura, Atsushi Yoshiki, Kathryn E. Hentges, Loydie Jerome-Majeweska, Wesley Chan, Ronald Redder, Toshiaki Nakashiba, Johnathan Ballard, Jinke D’Hont, Marie-Claude Beauchamp, Katharine M. Dibb, Kazuto Yoshimi, Donald W. Harms, Volkhard Lindner, Shinya Ayabe, Surinder K. Batra, Francisco J. Carrillo-Salinas, Gloria Lopez-Castejon, Yuko Kotani, Xian De Liu, Hanying Chen, Yu Zhang, Anyonya R. Guntur, Sanae Ogiwara, Yayoi Kunihiro, Masamitsu Konno, Jean Francois Schmouth

Publikováno v: Genome Biology, Vol 22, Iss 1, Pp 1-4 (2021)
Genome Biology
GENOME BIOLOGY

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c136f7a6e112f46e419a065ac263ae
https://pubmed.ncbi.nlm.nih.gov/33827646

Unravelling the pro-tumorigenic role of innate immune pattern recognition receptors in the gastric compartment

Autor: Ruby Dawson, Brendan J. Jenkins

Dysregulation of the immune system plays a critical role in driving gastric tumorigenesis, as evidenced by the established link between chronic gastric inflammation triggered by infection with gastric pathogens (i.e., Helicobacter pylori, Epstein–B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54b8dd954baa7116e7c0cb2411226c2f
https://doi.org/10.1016/b978-0-323-85563-1.00007-1

Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles : a multi-center evaluation

Autor: Antony Adamson, Ane M. Salvador, Pilar Alcaide, Joseph M. Miano, Gaetan Burgio, Satoru Takahashi, David Brough, Bernard Keavney, Anne Harrington, Surinder K. Batra, Francisco J. Carrillo-Salinas, Lucy Liaw, Kathryn E. Hentges, Imayavaramban Lakshmanan, Fumihiro Sugiyama, Seiya Mizuno, Catherine B. Lawrence, Yuichi Obata, Karan Sharma, Kevin C K Lloyd, Mariette Ouellet, Andrew S. I. Loudon, Nay Chi Khin, Yo-ichi Nabeshima, Xin Yi, Masato Ohtsuka, Huiping Guo, Channabasavaiah B. Gurumurthy, Yoshihiro Uno, William R. Thompson, Hanying Chen, Jinke D’Hont, Daniel J. Garry, Sandra Piltz, Lora Starrs, Clifford J. Rosen, Benjamin Morpurgo, Yuko Yamauchi, Nikki Ross, Aidan R. O’Brien, Yuko Kotani, Chad Smith, Tino Hochepied, Loydie A. Jerome-Majewska, Koji Nakade, Ilka Pinz, James D. Eudy, Amy Gonzales, Paul Q. Thomas, Wesley Chan, Leif Oxburgh, Leen Vanhoutte, Mitra Cowan, Radislav Sedlacek, Donald W. Harms, Volkhard Lindner, Marie-Claude Beauchamp, Tomoji Mashimo, Larisa Ryzhova, Jenna Lowe, Joshua A. Wood, Brandon J. Willis, Jan Parker-Thornburg, Gloria Lopez-Castejon, Victoria E. DeMambro, Ronald Redder, Shinya Ayabe, Mizuho Iwama, Satyabrata Das, Ruby Dawson, Tomohiro Tanaka, Toshiaki Nakashiba, Eric Jonasch, Andrew W. Trafford, Hiromi Miura, Hao Zhu, Yu Zhang, Guillaume Bernas, Kazuto Yoshimi, Neil E. Humphreys, John H. Adams, Kathleen A. Becker, Petr Kasparek, Yoshiki Miyasaka, Anyonya R. Guntur, Hideshi Ishii, Sabrina Shameen Alam, Katrien Staes, Lin Li, Shiho Imai, Katherine J. Motyl, Kenichi Nakashima, Katharine M. Dibb, Johnathan Ballard, Frederique Vanrockeghem, Mark T. Ruhe, Jing Gao, Christian S. Wright, Xian De Liu, Andrei Golovko, Rolen M. Quadros, David W. Ray, Atsushi Yoshiki, Catherine Larochelle, Masamitsu Konno, Lin Gan, Michelle Karolak, Jean Francois Schmouth, Xuesong Zhang, Taiji Matsusaka, Yayoi Kunihiro, Sanae Ogiwara, Moorthy P. Ponnusamy

Publikováno v: GENOME BIOLOGY
Genome Biology, Vol 20, Iss 1, Pp 1-14 (2019)
Gurumurthy, C B, O'Brien, A R, Quadros, R M, Adams, J, Alcaide, P, Ayabe, S, Ballard, J, Batra, S K, Beauchamp, M-C, Becker, K A, Bernas, G, Brough, D, Carrillo-Salinas, F, Chan, W, Chen, H, Dawson, R, Demambro, V, D'Hont, J, Dibb, K M, Eudy, J D, Gan, L, Gao, J, Gonzales, A, Guntur, A R, Guo, H, Harms, D W, Harrington, A, Hentges, K E, Humphreys, N, Imai, S, Ishii, H, Iwama, M, Jonasch, E, Karolak, M, Keavney, B, Khin, N-C, Konno, M, Kotani, Y, Kunihiro, Y, Lakshmanan, I, Larochelle, C, Lawrence, C B, Li, L, Lindner, V, Liu, X-D, Lopez-Castejon, G, Loudon, A, Lowe, J, Jerome-Majewska, L A, Matsusaka, T, Miura, H, Miyasaka, Y, Morpurgo, B, Motyl, K, Nabeshima, Y-I, Nakade, K, Nakashiba, T, Nakashima, K, Obata, Y, Ogiwara, S, Ouellet, M, Oxburgh, L, Piltz, S, Pinz, I, Ponnusamy, M P, Ray, D, Redder, R J, Rosen, C J, Ross, N, Ruhe, M T, Ryzhova, L, Salvador, A M, Alam, S S, Sedlacek, R, Sharma, K, Smith, C, Staes, K, Starrs, L, Sugiyama, F, Takahashi, S, Tanaka, T, Trafford, A W, Uno, Y, Vanhoutte, L, Vanrockeghem, F, Willis, B J, Wright, C S, Yamauchi, Y, Yi, X, Yoshimi, K, Zhang, X, Zhang, Y, Ohtsuka, M, Das, S, Garry, D J, Hochepied, T, Thomas, P, Parker-Thornburg, J, Adamson, A D, Yoshiki, A, Schmouth, J-F, Golovko, A, Thompson, W R, Lloyd, K C K, Wood, J A, Cowan, M, Mashimo, T, Mizuno, S, Zhu, H, Kasparek, P, Liaw, L, Miano, J M & Burgio, G 2019, ' Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation ', Genome biology, vol. 20, no. 1, 171 . https://doi.org/10.1186/s13059-019-1776-2, https://doi.org/10.1186/s13059-019-1776-2
Genome Biology

Background CRISPR-Cas9 gene-editing technology has facilitated the generation of knockout mice, providing an alternative to cumbersome and time-consuming traditional embryonic stem cell-based methods. An earlier study reported up to 16% efficiency in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289a8204ff6c6cb86fbd647d343d1846
https://biblio.ugent.be/publication/8628939/file/8628940