A novel mouse model for familial hypocalciuric hypercalcemia (FHH1) reveals PTH-dependent and independent CaSR defects.

Autor: Küng CJ; Institute of Physiology, University of Zürich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Daryadel A; Institute of Physiology, University of Zürich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Fuente R; Institute of Physiology, University of Zürich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.; Department of Morphology and Cellular Biology, University of Oviedo, Oviedo, Spain., Haykir B; Institute of Physiology, University of Zürich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., de Angelis MH; Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Lehrstuhl Für Experimentelle Genetik, Technische Universität München, Freising-Weihenstephan, Germany.; Member of German Center for Diabetes Research (DZD), Neuherberg, Germany., Hernando N; Institute of Physiology, University of Zürich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Rubio-Aliaga I; Institute of Physiology, University of Zürich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Wagner CA; Institute of Physiology, University of Zürich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland. Wagnerca@access.uzh.ch.

Publikováno v: Pflugers Archiv : European journal of physiology [Pflugers Arch] 2024 May; Vol. 476 (5), pp. 833-845. Date of Electronic Publication: 2024 Feb 22.

Extracellular sodium regulates fibroblast growth factor 23 (FGF23) formation.

Autor: Radvanyi Z; Institute of Anatomy, University of Zurich, Zurich, Switzerland; Swiss National Centre of Competence in Research 'Kidney Control of Homeostasis', Zurich, Switzerland., Yoo EJ; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea., Kandasamy P; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, Inselspital, University of Bern, Bern, Switzerland., Salas-Bastos A; Institute of Anatomy, University of Zurich, Zurich, Switzerland., Monnerat S; Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland; Department of Clinical Research, University of Basel, Basel, Switzerland., Refardt J; Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland; Department of Clinical Research, University of Basel, Basel, Switzerland., Christ-Crain M; Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland; Department of Clinical Research, University of Basel, Basel, Switzerland., Hayashi H; Department of Animal Sciences, Teikyo University of Science, Yamanashi, Japan., Kondo Y; Department of Animal Sciences, Teikyo University of Science, Yamanashi, Japan., Jantsch J; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany; Institute for Medical Microbiology, Immunology, and Hygiene, and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Rubio-Aliaga I; Swiss National Centre of Competence in Research 'Kidney Control of Homeostasis', Zurich, Switzerland; Institute of Physiology, University of Zurich, Zurich, Switzerland., Sommer L; Institute of Anatomy, University of Zurich, Zurich, Switzerland., Wagner CA; Swiss National Centre of Competence in Research 'Kidney Control of Homeostasis', Zurich, Switzerland; Institute of Physiology, University of Zurich, Zurich, Switzerland., Hediger MA; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, Inselspital, University of Bern, Bern, Switzerland., Kwon HM; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea., Loffing J; Institute of Anatomy, University of Zurich, Zurich, Switzerland; Swiss National Centre of Competence in Research 'Kidney Control of Homeostasis', Zurich, Switzerland., Pathare G; Institute of Anatomy, University of Zurich, Zurich, Switzerland; Swiss National Centre of Competence in Research 'Kidney Control of Homeostasis', Zurich, Switzerland. Electronic address: ganesh.pathare@anatomy.uzh.ch.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2024 Jan; Vol. 300 (1), pp. 105480. Date of Electronic Publication: 2023 Nov 21.

Intact FGF23 predicts serum phosphate improvement after combined nicotinamide and phosphate binder treatment in hemodialysis patients.

Autor: Egli-Spichtig D; Institute of Physiology, University of Zurich, 8057 Zurich, Switzerland, and National Center of Competence in Research NCCR Kidney.CH., Hamid AK; Institute of Physiology, University of Zurich, 8057 Zurich, Switzerland, and National Center of Competence in Research NCCR Kidney.CH., Arroyo EMP; Institute of Physiology, University of Zurich, 8057 Zurich, Switzerland, and National Center of Competence in Research NCCR Kidney.CH., Ketteler M; Robert Bosch Hospital, Department of General Internal Medicine and Nephrology, Stuttgart, Germany., Wiecek A; Department of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland., Rosenkranz AR; Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Pasch A; Calciscon AG, 2503 Biel, Switzerland.; Department of Nephrology, Lindenhofspital, 3012 Bern, Switzerland.; Department of Physiology and Pathophysiology, Johannes Kepler University Linz, Linz, Austria., Lorenz H; Buero fuer Biometrie und Statistik, Neuberg, Germany., Hellmann B; MEDICE Arzneimittel Pütter GmbH & Co KG, Iserlohn, Germany., Karus M; MEDICE Arzneimittel Pütter GmbH & Co KG, Iserlohn, Germany., Ammer R; MEDICE Arzneimittel Pütter GmbH & Co KG, Iserlohn, Germany.; Department of Medicine D, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital of Münster, Münster, Germany., Rubio-Aliaga I; Institute of Physiology, University of Zurich, 8057 Zurich, Switzerland, and National Center of Competence in Research NCCR Kidney.CH., Wagner CA; Institute of Physiology, University of Zurich, 8057 Zurich, Switzerland, and National Center of Competence in Research NCCR Kidney.CH.

Publikováno v: Clinical kidney journal [Clin Kidney J] 2023 Mar 10; Vol. 16 (10), pp. 1622-1633. Date of Electronic Publication: 2023 Mar 10 (Print Publication: 2023).

Phosphate intake, hyperphosphatemia, and kidney function.

Autor: Rubio-Aliaga I; Institute of Physiology, National Center of Competence in Research NCCR Kidney.CH, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland. isabel.rubioaliaga@uzh.ch., Krapf R; Synlab Suisse, 6002, Lucerne, Switzerland.; Department of Medicine, University of Basel, 4056, Basel, Switzerland.

Publikováno v: Pflugers Archiv : European journal of physiology [Pflugers Arch] 2022 Aug; Vol. 474 (8), pp. 935-947. Date of Electronic Publication: 2022 May 05.

Systemic Jak1 activation causes extrarenal calcitriol production and skeletal alterations provoking stunted growth.

Autor: Fuente R; Institute of Physiology, University of Zurich, Zurich, Switzerland.; National Center of Competence in Research NCCR Kidney.CH, Zurich, Switzerland.; Division of Pediatrics, University of Oviedo, Oviedo, Spain., Gehring N; Institute of Physiology, University of Zurich, Zurich, Switzerland.; National Center of Competence in Research NCCR Kidney.CH, Zurich, Switzerland., Bettoni C; Institute of Physiology, University of Zurich, Zurich, Switzerland.; National Center of Competence in Research NCCR Kidney.CH, Zurich, Switzerland., Gil-Peña H; Division of Pediatrics, University of Oviedo, Oviedo, Spain., Alonso-Durán L; Division of Pediatrics, University of Oviedo, Oviedo, Spain., Michalke B; Department of Environmental Science, Research Unit Analytical, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany., Santos F; Division of Pediatrics, University of Oviedo, Oviedo, Spain.; Department of Pediatrics, Hospital Universitario Central de Asturias, Oviedo, Spain., Wagner CA; Institute of Physiology, University of Zurich, Zurich, Switzerland.; National Center of Competence in Research NCCR Kidney.CH, Zurich, Switzerland., Rubio-Aliaga I; Institute of Physiology, University of Zurich, Zurich, Switzerland.; National Center of Competence in Research NCCR Kidney.CH, Zurich, Switzerland.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Jul; Vol. 35 (7), pp. e21721.