Výsledky vyhledávání - "Rubino, Patrizia"

Akademický článek

RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets.

Autor: Perconti, Giovanni¹ (AUTHOR) giovanni.perconti@ibim.cnr.it, Rubino, Patrizia¹ (AUTHOR) patrizia.rubino@ibim.cnr.it, Contino, Flavia² (AUTHOR) flavia.contino@unipa.it, Bivona, Serena^2,3 (AUTHOR) serena.bivona@unipa.it, Bertolazzi, Giorgio⁴ (AUTHOR) giorgio.bertolaz@gmail.com, Tumminello, Michele⁴ (AUTHOR) michele.tumminello@unipa.it, Feo, Salvatore^2,3 (AUTHOR) salvatore.feo@unipa.it, Giallongo, Agata¹ (AUTHOR) agata.giallongo@ibim.cnr.it, Coronnello, Claudia^1,5 (AUTHOR) ccoronnello@fondazionerimed.com

Publikováno v: BMC Bioinformatics. 4/18/2019 Supplement4, Vol. 20 Issue 4, p1-13. 13p. 1 Chart, 5 Graphs.

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Additional file 5: of RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets

Autor: Perconti, Giovanni, Rubino, Patrizia, Contino, Flavia, Bivona, Serena, Bertolazzi, Giorgio, Tumminello, Michele, Feo, Salvatore, Giallongo, Agata, Coronnello, Claudia

Venn diagram of lists of enriched genes. The considered lists are: AGO2-IP (UP_AGO2 set), the list of enriched genes detected by Fan et al. [13] (UP_AGO2_Fan) and our list of enriched genes in GW182-IP sample (UP_GW182). The reported p-values refer t

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Additional file 1: of RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets

Autor: Perconti, Giovanni, Rubino, Patrizia, Contino, Flavia, Bivona, Serena, Bertolazzi, Giorgio, Tumminello, Michele, Feo, Salvatore, Giallongo, Agata, Coronnello, Claudia

Analysis of miRNA expression in AGO2 and GW182-IP samples. a) miRNA expression level in AGO2-IP samples (average value from the three performed experiments) vs the expression level in IN samples (average value from the three performed experiments). T

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Additional file 8: of RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets

Autor: Perconti, Giovanni, Rubino, Patrizia, Contino, Flavia, Bivona, Serena, Bertolazzi, Giorgio, Tumminello, Michele, Feo, Salvatore, Giallongo, Agata, Coronnello, Claudia

Empirical Cumulative Distribution Function of 3â UTR and coding region length of IP-Enriched genes. Enriched genes in AGO (1â 4) and in GW182 protein family IP selected by considering log2 IP-Enrichment of transcript greater than 1. Data are downlo

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Additional file 9: of RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets

Autor: Perconti, Giovanni, Rubino, Patrizia, Contino, Flavia, Bivona, Serena, Bertolazzi, Giorgio, Tumminello, Michele, Feo, Salvatore, Giallongo, Agata, Coronnello, Claudia

Summary of miRNA expression profiles switch between experiment replicas. ROC analysis of F6&F4d SVM model trained with variables calculated with miRNA expression profiles from each of the three anti-AGO2 RIP experiments. SVM models were used to class

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Additional file 6: of RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets

Autor: Perconti, Giovanni, Rubino, Patrizia, Contino, Flavia, Bivona, Serena, Bertolazzi, Giorgio, Tumminello, Michele, Feo, Salvatore, Giallongo, Agata, Coronnello, Claudia

Wilcoxon test p-values summary. Wilcoxon test p-values (log10) obtained by comparing the variable values associated with the enriched/underrepresented genes sets. Three different miRNA target prediction tools (Targetscan, PITA and miRanda) were used

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Additional file 7: of RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets

Autor: Perconti, Giovanni, Rubino, Patrizia, Contino, Flavia, Bivona, Serena, Bertolazzi, Giorgio, Tumminello, Michele, Feo, Salvatore, Giallongo, Agata, Coronnello, Claudia

Summary of miRNA expression profiles shuffling effects. ROC analysis was performed to evaluate the performance of F6 and F4d variables, computed with simulated miRNA profiles, in distinguishing enriched/underrepresented genes in AGO2 or GW182-IP samp

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