Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rubina Koglgruber"'
Autor:
Riem Gawish, Philipp Starkl, Lisabeth Pimenov, Anastasiya Hladik, Karin Lakovits, Felicitas Oberndorfer, Shane JF Cronin, Anna Ohradanova-Repic, Gerald Wirnsberger, Benedikt Agerer, Lukas Endler, Tümay Capraz, Jan W Perthold, Domagoj Cikes, Rubina Koglgruber, Astrid Hagelkruys, Nuria Montserrat, Ali Mirazimi, Louis Boon, Hannes Stockinger, Andreas Bergthaler, Chris Oostenbrink, Josef M Penninger, Sylvia Knapp
Publikováno v:
eLife, Vol 11 (2022)
Despite tremendous progress in the understanding of COVID-19, mechanistic insight into immunological, disease-driving factors remains limited. We generated maVie16, a mouse-adapted SARS-CoV-2, by serial passaging of a human isolate. In silico modelin
Externí odkaz:
https://doaj.org/article/c49137ed8a364fa0b46437d84e5c0342
Autor:
Philipp Starkl, Riem Gawish, Lisabeth Pimenov, Anastasiya Hladik, Karin Lakovits, Felicitas Oberndorfer, Shane JF Cronin, Anna Ohradanova-Repic, Gerald Wirnsberger, Benedikt Agerer, Lukas Endler, Tümay Capraz, Jan W Perthold, Domagoj Cikes, Rubina Koglgruber, Astrid Hagelkruys, Nuria Montserrat, Ali Mirazimi, Louis Boon, Hannes Stockinger, Andreas Bergthaler, Chris Oostenbrink, Josef M Penninger, Sylvia Knapp
Publikováno v:
eLife, Vol 11 (2022)
Dipòsit Digital de la UB
Universidad de Barcelona
eLife
Elife
Dipòsit Digital de la UB
Universidad de Barcelona
eLife
Elife
Despite tremendous progress in the understanding of COVID-19, mechanistic insight into immunological, disease-driving factors remains limited. We generated maVie16, a mouse-adapted SARS-CoV-2, by serial passaging of a human isolate. In silico modelin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd882eda2890a3c465b4020f59b1b331
https://elifesciences.org/articles/74623
https://elifesciences.org/articles/74623
Autor:
Astrid Hagelkruys, Marion Horrer, Jasmin Taubenschmid-Stowers, Anoop Kavirayani, Maria Novatchkova, Michael Orthofer, Tsung-Pin Pai, Domagoj Cikes, Sergei Zhuk, Meritxell Balmaña, Christopher Esk, Rubina Koglgruber, Paul Moeseneder, Jelena Lazovic, Lydia M. Zopf, Shane J.F. Cronin, Ulrich Elling, Jürgen A. Knoblich, Josef M. Penninger
Publikováno v:
Science Advances, 8 (44)
The HUSH (human silencing hub) complex contains the H3K9me3 binding protein M-phase phosphoprotein 8 (MPP8) and recruits the histone methyltransferase SETDB1 as well as Microrchidia CW-type zinc finger protein 2 (MORC2). Functional and mechanistic st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c7aeac0b55b660888249551a94ffda
Autor:
Maria Novatchkova, Meritxell Balmaña, Shane J. F. Cronin, Anoop Kavirayani, Astrid Hagelkruys, Domagoj Cikes, Josef M. Penninger, Michael Orthofer, Christopher Esk, Juergen A. Knoblich, Rubina Koglgruber, Sergei Zhuk, Ulrich Elling, Tsung-Pin Pai, Marion Horrer, Jasmin Taubenschmid-Stowers
Fine-tuning of neural connectivity is important for cerebral functions and brain evolution. Protocadherins provide barcodes for neuronal identity as well as synapse formation and expansion of protocadherin cluster genes has been linked to advanced co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9225e6361d2febef1aeb1ee67e280e5
https://doi.org/10.1101/2021.11.29.466909
https://doi.org/10.1101/2021.11.29.466909
Autor:
Shane J. F. Cronin, Dagmar Bancher-Todesca, Magdalena Paolino, Jürgen Harreiter, Josef M. Penninger, Verena Sigl, Andrea J. White, Iris Uribesalgo, Georg A. Holländer, Lukas Kenner, Alexandra Kautzky-Willer, Esther Rauscher, Michael Schuster, Christoph Bock, Rubina Koglgruber, Thomas Penz, Blanka Pranjic, Juan Pablo Fededa, Maria Novatchkova, Graham Anderson, Sabine Dekan
Publikováno v:
Nature
Successful pregnancies rely on adaptations within the mother1, including marked changes within the immune system2. It has long been known that the thymus, the central lymphoid organ, changes markedly during pregnancy3. However, the molecular basis an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4a0dfb4b7f9e9984544e32c5e2c4a3
https://europepmc.org/articles/PMC7116618/
https://europepmc.org/articles/PMC7116618/
Autor:
Luigi Tortola, Rubina Koglgruber, Gerald Wirnsberger, Christoph Klein, Miriam Wöhner, Melanie Kogler, Meinrad Busslinger, Josef M. Penninger, Astrid Hagelkruys, Johannes Stadlmann, Maria Novatchkova, David Hoffmann, Andreas Bergthaler, Georg Schett, Bojan Vilagos, Marion Horrer, Peter Bönelt, Gustav Jonsson, Ulrike Steffen
Publikováno v:
The Journal of Experimental Medicine
Jagn1 deficiency results in alterations in the endoplasmic reticulum (ER) and Golgi apparatus of antibody-producing cells, reduced antibody secretion, and aberrant IgG N-glycosylation. The data uncover a key role for JAGN1 and ER stress in antibody g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035ce1e26b0e1bac78990b6f7111f245
https://pubmed.ncbi.nlm.nih.gov/32930709
https://pubmed.ncbi.nlm.nih.gov/32930709
Autor:
Shane J. F. Cronin, Toshikatsu Hanada, Laura Mondragón, Peng Zhang, Valentina Sica, Tsung-Pin Pai, Guido Kroemer, Blanka Pranjic, Shuan Rao, Ivona Kozieradzki, Oliver Kepp, Josef M. Penninger, Daniel Schramek, Helmut Popper, Alexander Lercher, Alexander Jais, Zhigang She, Franz Quehenberger, Katharina Haigh, Nazanine Modjtahedi, Iris Uribesalgo, Andreas Bergthaler, Masahiro Onji, Thomas Köcher, Malgorzata Rak, Rubina Koglgruber, Lukas Kenner, Gautier Stoll, Marion Leduc, Jody J. Haigh, Reiko Hanada, Kaican Cai
Publikováno v:
Cell Research
Cell Research, Nature Publishing Group, 2019, 29 (7), pp.579-591. ⟨10.1038/s41422-019-0181-4⟩
Cell Res
Cell Research, Nature Publishing Group, 2019, 29 (7), pp.579-591. ⟨10.1038/s41422-019-0181-4⟩
Cell Res
International audience; Cancer is a major and still increasing cause of death in humans. Most cancer cells have a fundamentally different metabolic profile from that of normal tissue. This shift away from mitochondrial ATP synthesis via oxidative pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4daf646473a9eecb7d69a5b566f7dd
https://hal.archives-ouvertes.fr/hal-02355955
https://hal.archives-ouvertes.fr/hal-02355955
Autor:
Elisa Cora, Sai Lakshmi Subramanian, Vladimir Benes, Mihoko Hosokawa, Zhaolin Yang, Shinichiro Chuma, Philipp Berninger, Michael Reuter, Josef M. Penninger, Andrés Palencia, Ravi Sachidanandam, Ramesh S. Pillai, Jordi Xiol, Rubina Koglgruber
Publikováno v:
Molecular Cell
Epigenetic silencing of transposons by Piwi-interacting RNAs (piRNAs) constitutes an RNA-based genome defense mechanism. Piwi endonuclease action amplifies the piRNA pool by generating new piRNAs from target transcripts by a poorly understood mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163d5fa094a42910ea7b99eb27d424fd
https://doi.org/10.1016/j.molcel.2012.07.019
https://doi.org/10.1016/j.molcel.2012.07.019
Autor:
Andrew A. Hicks, Ulrich Elling, Rolf Bodmer, Arne Pfeufer, Yumiko Imai, Keiichi Fukuda, J. Andrew Pospisilik, Mitsushige Murata, Hiroshi Nishina, G. Gregory Neely, Liyong Zhang, Karen Ocorr, Anthony Cammarato, Susumu Fujisawa, Sai Subramaniam, Keiji Kuba, Cui ping Xia, Christian Berger, Suchir Arora, Takako Usami, Hiroyuki Yamakawa, Kazuya Isobe, Peter P. Pramstaller, Lisa Elmén, Mitsuaki Isobe, Vaijayanti Gupta, Rubina Koglgruber, Alex C. Keene, Nakissa N. Alayari, Rinku Ranjan Sarangi, Debasis Dan, Akinori Kimura, Maria Novatchkova, Sabine Amann, Josef M. Penninger
Publikováno v:
Cell. (1):142-153
SummaryHeart diseases are the most common causes of morbidity and death in humans. Using cardiac-specific RNAi-silencing in Drosophila, we knocked down 7061 evolutionarily conserved genes under conditions of stress. We present a first global roadmap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08d484605f66dd69ee7548c13c0a196