Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Rubenstein JLR"'
Autor:
Silberberg, SN, Taher, L, Lindtner, S, Sandberg, M, Nord, AS, Vogt, D, Mckinsey, GL, Hoch, R, Pattabiraman, K, Zhang, D, Ferran, JL, Rajkovic, A, Golonzhka, O, Kim, C, Zeng, H, Puelles, L, Visel, A, Rubenstein, JLR
Publikováno v:
Neuron, vol 92, iss 1
Silberberg, SN; Taher, L; Lindtner, S; Sandberg, M; Nord, AS; Vogt, D; et al.(2016). Subpallial Enhancer Transgenic Lines: a Data and Tool Resource to Study Transcriptional Regulation of GABAergic Cell Fate. Neuron, 92(1), 59-74. doi: 10.1016/j.neuron.2016.09.027. UCSF: Retrieved from: http://www.escholarship.org/uc/item/79k1j6xd
Silberberg, SN; Taher, L; Lindtner, S; Sandberg, M; Nord, AS; Vogt, D; et al.(2016). Subpallial Enhancer Transgenic Lines: a Data and Tool Resource to Study Transcriptional Regulation of GABAergic Cell Fate. Neuron, 92(1), 59-74. doi: 10.1016/j.neuron.2016.09.027. UCSF: Retrieved from: http://www.escholarship.org/uc/item/79k1j6xd
© 2016 Elsevier Inc. Elucidating the transcriptional circuitry controlling forebrain development requires an understanding of enhancer activity and regulation. We generated stable transgenic mouse lines that express CreERT2and GFP from ten different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a2983fdfebcbbfb15cb1a6fe2c2240f0
https://escholarship.org/uc/item/79k1j6xd
https://escholarship.org/uc/item/79k1j6xd
Autor:
Parchem, RJ, Moore, N, Fish, JL, Parchem, JG, Braga, TT, Shenoy, A, Oldham, MC, Rubenstein, JLR, Schneider, RA, Blelloch, R
Publikováno v:
Parchem, RJ; Parchem, RJ; Moore, N; Moore, N; Fish, JL; Parchem, JG; et al.(2015). MiR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability. Cell Reports. doi: 10.1016/j.celrep.2015.06.074. UCSF: Retrieved from: http://www.escholarship.org/uc/item/4rp055hd
© 2015 The Authors. The evolutionarily conserved miR-302 family of microRNAs is expressed during early mammalian embryonic development. Here, we report that deletion of miR-302a-d in mice results in a fully penetrant late embryonic lethal phenotype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::4249c4c1655e1cf168209b630b71d70c
http://www.escholarship.org/uc/item/4rp055hd
http://www.escholarship.org/uc/item/4rp055hd
Publikováno v:
Rubenstein, John; Ferran, JL; Puelles, L; & Rubenstein, JLR. (2015). Molecular codes defining rostrocaudal domains in the embryonic mouse hypothalamus. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/37d5t4s3
© 2015 Ferran, Puelles and Rubenstein.The prosomeric model proposes that the hypothalamus is a rostral forebrain entity, placed ventral to the telencephalon and rostral to the diencephalon. Gene expression markers differentially label molecularly di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::adfbedd4df273a11d436ea022a3e93f3
http://www.escholarship.org/uc/item/37d5t4s3
http://www.escholarship.org/uc/item/37d5t4s3
Publikováno v:
Rubenstein, John; Hoch, RV; Clarke, JA; & Rubenstein, JLR. (2015). Fgf signaling controls the telencephalic distribution of Fgf-expressing progenitors generated in the rostral patterning center. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/3mf0f11f
© 2015 Hoch et al.Background: The rostral patterning center (RPC) secretes multiple fibroblast growth factors (Fgfs) essential for telencephalon growth and patterning. Fgf expression patterns suggest that they mark functionally distinct RPC subdomai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::4f45428497bea5b3a552251bae4536e7
http://www.escholarship.org/uc/item/3mf0f11f
http://www.escholarship.org/uc/item/3mf0f11f
Publikováno v:
Rubenstein, John; Puelles, L; & Rubenstein, JLR. (2015). A new scenario of hypothalamic organization: Rationale of new hypotheses introduced in the updated prosomeric model. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1wj329wh
© 2015 Puelles and Rubenstein.In this essay, we aim to explore in depth the new concept of the hypothalamus that was presented in the updated prosomeric model (Puelles et al., 2012b; Allen Developing Mouse Brain Atlas). Initial sections deal with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::6ea8ede8085d0d55225ec8edfed31db5
http://www.escholarship.org/uc/item/1wj329wh
http://www.escholarship.org/uc/item/1wj329wh
Autor:
Rubenstein, John, Pollard, Katherine, Capra, JA, Erwin, GD, Mckinsey, G, Rubenstein, JLR, Pollard, KS
Publikováno v:
Rubenstein, John; Pollard, Katherine; Capra, JA; Erwin, GD; Mckinsey, G; Rubenstein, JLR; et al.(2013). Many human accelerated regions are developmental enhancers. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/9kc2f3m3
The genetic changes underlying the dramatic differences in form and function between humans and other primates are largely unknown, although it is clear that gene regulatory changes play an important role. To identify regulatory sequences with potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::73383188f0418f17452c899fb634480d
http://www.escholarship.org/uc/item/9kc2f3m3
http://www.escholarship.org/uc/item/9kc2f3m3
Autor:
Rubenstein, John, Wang, B, Long, JE, Flandin, P, Pla, R, Waclaw, RR, Campbell, K, Rubenstein, JLR
Publikováno v:
Rubenstein, John; Wang, B; Long, JE; Flandin, P; Pla, R; Waclaw, RR; et al.(2013). Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6kz945qb
Mice lacking the Dlx1 and Dlx2 homeobox genes (Dlx1/2 mutants) have severe deficits in subpallial differentiation, including overexpression of the Gsx1 and Gsx2 homeobox genes. To investigate whether Gsx overexpression contributes to the Dlx1/2 mutan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::e63034d39bdc8951ec9300fa0aa7263a
http://www.escholarship.org/uc/item/6kz945qb
http://www.escholarship.org/uc/item/6kz945qb
Autor:
Rubenstein, John, Pleasure, Samuel, Harrison-Uy, SJ, Siegenthaler, JA, Faedo, A, Rubenstein, JLR, Pleasure, SJ
Publikováno v:
Rubenstein, John; Pleasure, Samuel; Harrison-Uy, SJ; Siegenthaler, JA; Faedo, A; Rubenstein, JLR; et al.(2013). CoupTFI Interacts with Retinoic Acid Signaling during Cortical Development. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7g8368mr
We examined the role of the orphan nuclear hormone receptor CoupTFI in mediating cortical development downstream of meningeal retinoic acid signaling. CoupTFI is a regulator of cortical development known to collaborate with retinoic acid (RA) signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::079f101d202ab26b518a4c74daf58a52
http://www.escholarship.org/uc/item/7g8368mr
http://www.escholarship.org/uc/item/7g8368mr
Autor:
Chao, HT, Chen, H, Samaco, RC, Xue, M, Chahrour, M, Yoo, J, Neul, JL, Gong, S, Lu, HC, Heintz, N, Ekker, M, Rubenstein, JLR, Noebels, JL, Rosenmund, C, Zoghbi, HY
Publikováno v:
Nature, vol 468, iss 7321
Chao, HT; Chen, H; Samaco, RC; Xue, M; Chahrour, M; Yoo, J; et al.(2010). Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature, 468(7321), 263-269. doi: 10.1038/nature09582. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/1zg4v62w
Chao, HT; Chen, H; Samaco, RC; Xue, M; Chahrour, M; Yoo, J; et al.(2010). Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature, 468(7321), 263-269. doi: 10.1038/nature09582. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/1zg4v62w
Mutations in the X-linked MECP2 gene, which encodes the transcriptional regulator methyl-CpG-binding protein 2 (MeCP2), cause Rett syndrome and several neurodevelopmental disorders including cognitive disorders, autism, juvenile-onset schizophrenia a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::87763f6c31f4d75ee388507df0ee9089
https://escholarship.org/uc/item/1zg4v62w
https://escholarship.org/uc/item/1zg4v62w
Publikováno v:
Huffman, K J; Garel, S; & Rubenstein, JLR. (2004). Fgf8 regulates the development of intra-neocortical projections. Journal of Neuroscience, 24(41), 8917-8923. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/5f82d1vk
The process of generating functionally distinct neocortical areas requires the formation of an intra-neocortical connectivity map. Here, we explore the early development of murine intra-neocortical projections and find that axons from rostral and cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::9b1f3ec62c02a5003a4a9e5e2fd78805
http://www.escholarship.org/uc/item/5f82d1vk
http://www.escholarship.org/uc/item/5f82d1vk