Adverse effects in the fish embryo acute toxicity (FET) test: a catalogue of unspecific morphological changes versus more specific effects in zebrafish (Danio rerio) embryos

Autor: Katharina Brotzmann, Ruben Strecker, Lisa Baumann, Thomas Braunbeck, Rebecca von Hellfeld

Publikováno v: Environmental Sciences Europe

Background The Fish Embryo Acute Toxicity (FET) test with the zebrafish (Danio rerio) embryo, the OECD test guideline (TG) 236, has been designed as an alternative for acute fish toxicity testing such as the OECD Acute Fish Toxicity Test (TG 203). To

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af7db05425d94a1af8dc4786f1b73c3
https://doi.org/10.1186/s12302-020-00398-3

Cartilage and bone malformations in the head of zebrafish (Danio rerio) embryos following exposure to disulfiram and acetic acid hydrazide

Autor: Ruben Strecker, Thomas Braunbeck, Stefan Weigt

Publikováno v: Toxicology and Applied Pharmacology. 268:221-231

In order to investigate teratogenic effects, especially on cartilage and bone formation, zebrafish embryos were exposed for 144h to the dithiocarbamate pesticide disulfiram (20-320μg/L) and acetic acid hydrazide (0.375-12g/L), a degradation product

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https://doi.org/10.1016/j.taap.2013.01.023

OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing

Autor: Thomas Braunbeck, Przemyslaw Fochtman, Marlies Halder, Stefan Weigt, Adam Lillicrap, Gregory J. Carr, Katharina Schneider, Francois Busquet, Juliette Legler, Stefan Scholz, Anne Gourmelon, Christian Polleichtner, Evert-Jan van den Brandhof, Susanne Walter-Rohde, Carola Kussatz, Hilda Witters, Ruben Strecker, Scott E. Belanger, Fernando Martínez-Jerónimo, Edward Salinas, Helena Rzodeczko, Melanie Knöbel, P.H. Cenijn, Jane M. Rawlings, Andre Kleensang, Leo T.M. van der Ven, Nicole Hübler

Publikováno v: Regulatory Toxicology and Pharmacology
Busquet, F, Strecker, R, Rawlings, J M, Belanger, S E, Braunbeck, T, Carr, G J, Cenijn, P H, Fochtman, P, Gourmelon, A, Hübler, N, Kleensang, A, Knöbel, M, Kussatz, C, Legler, J, Lillicrap, A, Martínez-Jerónimo, F, Polleichtner, C, Rzodeczko, H, Salinas, E, Schneider, K E, Scholz, S, van den Brandhof, E J, van der Ven, L T, Walter-Rohde, S, Weigt, S, Witters, H & Halder, M 2014, ' OECD validation study to assess intra-and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing ', Regulatory Toxicology and Pharmacology, vol. 69, no. 3, pp. 496-511 . https://doi.org/10.1016/j.yrtph.2014.05.018
Regulatory Toxicology and Pharmacology, 69(3), 496-511. Academic Press Inc.

A The OECD validation study of the zebrafish embryo acute toxicity test (ZFET) for acute aquatic toxicity testing evaluated the ZFET reproducibility by testing 20 chemicals at 5 different concentrations in 3 independent runs in at least 3 laboratorie

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https://pubmed.ncbi.nlm.nih.gov/24874798

Oxygen requirements of zebrafish (Danio rerio) embryos in embryo toxicity tests with environmental samples

Autor: Henner Hollert, Thomas-Benjamin Seiler, Thomas Braunbeck, Ruben Strecker

Publikováno v: Comparative biochemistry and physiology. Toxicologypharmacology : CBP. 153(3)

The zebrafish embryo test is a widely used bioassay for the testing of chemicals, effluents and other types of environmental samples. Oxygen depletion in the testing of sediments and effluents is especially important and may be a confounding factor i

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https://pubmed.ncbi.nlm.nih.gov/21163368