Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ruben Serrano"'
Signal strength of STING activation determines cytokine plasticity and cell death in human monocytes
Autor:
Dieter Kabelitz, Michal Zarobkiewicz, Michelle Heib, Ruben Serrano, Monika Kunz, Guranda Chitadze, Dieter Adam, Christian Peters
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The cyclic GMP-AMP synthase (cGAS)/stimulator of interferon genes (STING) pathway is a cytosolic sensor of microbial and host-derived DNA and plays a key role in innate immunity. Activation of STING by cyclic dinucleotide (CDN) ligands in hu
Externí odkaz:
https://doaj.org/article/3035c3c9a9fd416a90405d012622c74c
Autor:
Ruben Serrano, Marcus Lettau, Michal Zarobkiewicz, Daniela Wesch, Christian Peters, Dieter Kabelitz
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Ligands for Stimulator of Interferon Genes (STING) receptor are under investigation as adjuvants in cancer therapy. Multiple effects have been described, including induction of immunogenic cell death and enhancement of CD8 T-cell mediated anti-tumor
Externí odkaz:
https://doaj.org/article/19fc892885484080a8cd912244d7279c
Autor:
Ruben Serrano, Christoph Coch, Christian Peters, Gunther Hartmann, Daniela Wesch, Dieter Kabelitz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Human Vγ9Vδ2 T cells recognize pyrophosphates produced by microbes and transformed cells and play a role in anti-infective immunity and tumor surveillance. Toll-like receptors (TLR) are pattern recognition receptors in innate immune cells
Externí odkaz:
https://doaj.org/article/b641f3f4ca8948f881ad01de1b5a59b8
Autor:
Birthe Bernicke, Nils Engelbogen, Katharina Klein, Jeanette Franzenburg, Christoph Borzikowsky, Christian Peters, Ottmar Janssen, Ralf Junker, Ruben Serrano, Dieter Kabelitz
Publikováno v:
Cells, Vol 11, Iss 9, p 1460 (2022)
In addition to its role in bone metabolism, vitamin D3 exerts immunomodulatory effects and has been proposed to contribute to seasonal variation of immune cells. This might be linked to higher vitamin D3 levels in summer than in winter due to differe
Externí odkaz:
https://doaj.org/article/b0d85ce058da4789a0f09847fad89282
Publikováno v:
Cells, Vol 9, Iss 9, p 1977 (2020)
The authors wish to make the following changes to their paper [...]
Externí odkaz:
https://doaj.org/article/3fec71665c9f4857973f81e8f237cebc
Publikováno v:
Cells, Vol 9, Iss 3, p 713 (2020)
Background: Human Vγ9Vδ2 γδ T cells can kill a variety of cancer cells and have attracted substantial interest for cancer immunotherapy. Toll-like receptor (TLR) ligands are promising adjuvants for cancer immunotherapy, but TLR7/8 ligand Resiquim
Externí odkaz:
https://doaj.org/article/1c5c4ce3e4af4386b8a0d50ab5e8d3bd
Autor:
Ruben Serrano Lozano
Publikováno v:
Revista de Estudios de la Administración Local y Autonómica, Iss 266 (1995)
Externí odkaz:
https://doaj.org/article/90030f2e56b34560b4c0bb70c6702a19
Publikováno v:
Revista Colombiana de Obstetricia y Ginecología, Vol 34, Iss 3 (1983)
Se revisaron las historias el ínicas y los hallazgos histólogicos de 100 mujeres con hemorragia uterina disfuncional. El 55% de ellas presentó ciclo irregular, hallazgos más frecuentes a medida que pasan los años. La mayoría de los endome
Externí odkaz:
https://doaj.org/article/bb7f5cb02c524c13923f04a48ab96ae3
Autor:
Rubén Serrano-Zulueta, Antonio Gómez-Sal, Ferrán Pauné, Elena Velado-Alonso, Jesús Garzón, Agustín Del Prado, Pedro María Herrera, Julio Majadas, Francesca Pasetti, Esther Prada-Llorente, Pablo Manzano
Publikováno v:
Nomadic Peoples, Vol 28, Iss 2, Pp 242-274 (2024)
After centuries as a flagship economic activity, pastoralism in Spain is today in danger of collapse due to the simultaneous processes of abandonment and industrialisation. With a consensus on the need to revert this decline, a characterisation of pa
Externí odkaz:
https://doaj.org/article/8aefd5fa4b9d4d6b8c76f675b3c58c2b
Publikováno v:
Cellular and Molecular Immunology
γδ T cells play uniquely important roles in stress surveillance and immunity for infections and carcinogenesis. Human γδ T cells recognize and kill transformed cells independently of human leukocyte antigen (HLA) restriction, which is an essentia