Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Ruben M. Markosyan"'
The late endosome-resident lipid bis(monoacylglycero)phosphate is a cofactor for Lassa virus fusion.
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009488 (2021)
Arenavirus entry into host cells occurs through a low pH-dependent fusion with late endosomes that is mediated by the viral glycoprotein complex (GPC). The mechanisms of GPC-mediated membrane fusion and of virus targeting to late endosomes are not we
Externí odkaz:
https://doaj.org/article/5ecf10d3dd3942ff9db4e038d0ab1a62
Autor:
Krishna C Suddala, Christine C Lee, Paul Meraner, Mariana Marin, Ruben M Markosyan, Tanay M Desai, Fredric S Cohen, Abraham L Brass, Gregory B Melikyan
Publikováno v:
PLoS Pathogens, Vol 15, Iss 1, p e1007532 (2019)
Late endosome-resident interferon-induced transmembrane protein 3 (IFITM3) inhibits fusion of diverse viruses, including Influenza A virus (IAV), by a poorly understood mechanism. Despite the broad antiviral activity of IFITM3, viruses like Lassa vir
Externí odkaz:
https://doaj.org/article/bb7e88a7ea7e48bba101a0b179a8890e
Autor:
Ruben M Markosyan, Chunhui Miao, Yi-Min Zheng, Gregory B Melikyan, Shan-Lu Liu, Fredric S Cohen
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005373 (2016)
Ebola virus (EBOV) is a highly pathogenic filovirus that causes hemorrhagic fever in humans and animals. Currently, how EBOV fuses its envelope membrane within an endosomal membrane to cause infection is poorly understood. We successfully measure cel
Externí odkaz:
https://doaj.org/article/f5b4ca879da24da298efb142cfc34fdc
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009488 (2021)
PLoS Pathogens
PLoS Pathogens
Arenavirus entry into host cells occurs through a low pH-dependent fusion with late endosomes that is mediated by the viral glycoprotein complex (GPC). The mechanisms of GPC-mediated membrane fusion and of virus targeting to late endosomes are not we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82c8d2fd6b7d121cc000b8e48bc5835
https://doi.org/10.1101/2021.03.22.436413
https://doi.org/10.1101/2021.03.22.436413
Autor:
Kun Li, Ruben M Markosyan, Yi-Min Zheng, Ottavia Golfetto, Brittani Bungart, Minghua Li, Shilei Ding, Yuxian He, Chen Liang, James C Lee, Enrico Gratton, Fredric S Cohen, Shan-Lu Liu
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003124 (2013)
The interferon-inducible transmembrane (IFITM) protein family represents a new class of cellular restriction factors that block early stages of viral replication; the underlying mechanism is currently not known. Here we provide evidence that IFITM pr
Externí odkaz:
https://doaj.org/article/ae9c1ce25cf940a8a362acfb23000ad3
Autor:
Ruben M Markosyan, Fredric S Cohen
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76174 (2013)
Voltage dependence of fusion induced by class II and class III viral fusion proteins was investigated. Class II proteins from Ross River and Sindbus virus and a mutant class III protein from Epstein Barr virus were found to induce cell-cell fusion th
Externí odkaz:
https://doaj.org/article/8d88b327755d4b0bb81dd9812ed95d98
Autor:
Fredric S. Cohen, Ronen Borenstein, Barbara A. Hanson, Ruben M. Markosyan, Nell S. Lurain, Daniel A. Nicholson, Maimoona S Bhutta, Lena Al-Harthi, Elisa S. Gallo, Srinivas D. Narasipura, Oren Shechter
Publikováno v:
Scientific reports, 10:4746
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Ginkgolic acids (GA) are alkylphenol constituents of the leaves and fruits of Ginkgo biloba. GA has shown pleiotropic effects in vitro, including: antitumor effects through inhibition of lipogenesis; decreased expression of invasion associated protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932c58a073386389ee6c3cd26173c874
https://doi.org/10.1038/s41598-020-61700-0
https://doi.org/10.1038/s41598-020-61700-0
Publikováno v:
Biophysical Journal. 121:75a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0423b7449a35c38432bc4b22320b567e
https://doi.org/10.1016/j.bpj.2021.11.2348
https://doi.org/10.1016/j.bpj.2021.11.2348
Publikováno v:
Biophysical Journal. 120:320a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb6c2b4b6cefb910f4c62f3ec95c1774
https://doi.org/10.1016/j.bpj.2020.11.2026
https://doi.org/10.1016/j.bpj.2020.11.2026
Autor:
Elisa S. Gallo, Srinivas D. Narasipura, Lena Al-Harthi, Ruben M. Markosyan, Daniel A. Nicholson, Barbara A. Hanson, Oren Shechter, Fredric S. Cohen, Maimoona S Bhutta, Ronen Borenstein, Nell S. Lurain
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Scientific Reports
Scientific Reports
Ginkgolic acids (GA) are alkylphenol constituents of the leaves and fruits of Ginkgo biloba. GA has shown pleiotropic effects in vitro, including: antitumor effects through inhibition of lipogenesis; decreased expression of invasion associated protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2d39b3c7f13fb08dd99ef38377ca9c
http://link.springer.com/article/10.1038/s41598-020-64445-y
http://link.springer.com/article/10.1038/s41598-020-64445-y