Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ruben Jimenez-Canino"'
Autor:
Basile Gravez, Antoine Tarjus, Ruben Jimenez-Canino, Soumaya El Moghrabi, Smail Messaoudi, Diego Alvarez de la Rosa, Frederic Jaisser
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73737 (2013)
Aldosterone binds to the mineralocorticoid receptor (MR) and exerts pleiotropic effects beyond enhancing renal sodium reabsorption. Excessive mineralocorticoid signaling is deleterious during the evolution of cardiac failure, as evidenced by the bene
Externí odkaz:
https://doaj.org/article/46f7d778118448d9b3b6bfff34848bb0
Autor:
Frederic Jaisser, Dawn E W Livingstone, Matthew A. Bailey, Alex Odermatt, Nicolette Farman, Ruben Jimenez-Canino, Fabián Lorenzo-Díaz, Diego Alvarez de la Rosa
Publikováno v:
Jiménez-Canino, R, Lorenzo-Díaz, F, Odermatt, A, Bailey, M A, Livingstone, D E W, Jaisser, F, Farman, N & Alvarez de la Rosa, D 2017, ' 11β-HSD2 SUMOylation Modulates Cortisol-induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation ', Endocrinology . https://doi.org/10.1210/en.2017-00440
The enzyme 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) has an essential role in aldosterone target tissues, conferring aldosterone selectivity for the mineralocorticoid receptor (MR) by converting 11β-hydroxyglucocorticoids to inactive 11-k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a048ba8ff35683c402e6d077da84dfff
https://hdl.handle.net/20.500.11820/5c759c6f-8606-4653-ae8a-52bcc804639e
https://hdl.handle.net/20.500.11820/5c759c6f-8606-4653-ae8a-52bcc804639e
Autor:
Fabián Lorenzo-Díaz, Nicolette Farman, Diego Alvarez de la Rosa, Teresa Giraldez, Frederic Jaisser, Ruben Jimenez-Canino
Publikováno v:
Endocrinology. 157(6)
The mineralocorticoid receptor (MR) is a member of the nuclear receptor superfamily that transduces the biological effects of corticosteroids. Its best-characterized role is to enhance transepithelial sodium reabsorption in response to increased aldo
Publikováno v:
The Journal of biological chemistry. 291(36)
Post-translational modification of steroid receptors allows fine-tuning different properties of this family of proteins, including stability, activation, or interaction with co-regulators. Recently, a novel effect of phosphorylation on steroid recept
Autor:
Miguel X. Fernandes, Teresa Giraldez, Diego Alvarez de la Rosa, Rosario González-Muñiz, Mercedes Martín-Martínez, Ruben Jimenez-Canino
Publikováno v:
The FASEB Journal. 29
Publikováno v:
The FASEB Journal. 28
The mineralocorticoid receptor (MR) is a nuclear receptor that transduces the biological effects of the corticosteroid hormone aldosterone, playing a key role in the regulation of transepithelial N...