Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ruben J de Boer"'
Epithelial argininosuccinate synthetase is dispensable for intestinal regeneration and tumorigenesis
Autor:
Jonathan H. M. van der Meer, Ruben J. de Boer, Bartolomeus J. Meijer, Wouter L. Smit, Jacqueline L. M. Vermeulen, Sander Meisner, Manon van Roest, Pim J. Koelink, Evelien Dekker, Theodorus B. M. Hakvoort, Jan Koster, Lukas J. A. C. Hawinkels, Jarom Heijmans, Eduard A. Struijs, Marja A. Boermeester, Gijs R. van den Brink, Vanesa Muncan
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Abstract The epithelial signaling pathways involved in damage and regeneration, and neoplastic transformation are known to be similar. We noted upregulation of argininosuccinate synthetase (ASS1) in hyperproliferative intestinal epithelium. Since ASS
Externí odkaz:
https://doaj.org/article/71fe891b64fe490ab76705ba74a38453
Autor:
Bartolomeus J. Meijer, Wouter L. Smit, Pim J. Koelink, Barbara F. Westendorp, Ruben J. de Boer, Jonathan H. M. van der Meer, Jacqueline L. M. Vermeulen, James C. Paton, Adrienne W. Paton, Jun Qin, Evelien Dekker, Vanesa Muncan, Gijs R. van den Brink, Jarom Heijmans
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Enforcing differentiation of cancer stem cells is considered as a potential strategy to sensitize colorectal cancer cells to irradiation and chemotherapy. Activation of the unfolded protein response, due to endoplasmic reticulum (ER) stress,
Externí odkaz:
https://doaj.org/article/24ebfc27c3394013a484ca3d122122e9
Autor:
Bartolomeus J. Meijer, Francesca P. Giugliano, Bart Baan, Jonathan H.M. van der Meer, Sander Meisner, Manon van Roest, Pim J. Koelink, Ruben J. de Boer, Nic Jones, Wolfgang Breitwieser, Nicole N. van der Wel, Manon E. Wildenberg, Gijs R. van den Brink, Jarom Heijmans, Vanesa Muncan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 23-42 (2020)
Background & Aims: Activation factor-1 transcription factor family members activating transcription factors 2 and 7 (ATF2 and ATF7) have highly redundant functions owing to highly homologous DNA binding sites. Their role in intestinal epithelial home
Externí odkaz:
https://doaj.org/article/5ca26a8b84574534a05a42331734351c
Autor:
Sander Meisner, Nic Jones, Pim J. Koelink, Wolfgang Breitwieser, Nicole N. van der Wel, F.P. Giugliano, Bart Baan, Bartolomeus J. Meijer, Ruben J. de Boer, Manon van Roest, Vanesa Muncan, Gijs R. van den Brink, Jarom Heijmans, Jonathan H. M. van der Meer, Manon E. Wildenberg
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, 10(1), 23-42. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 23-42 (2020)
Cellular and molecular gastroenterology and hepatology, 10(1), 23-42. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 23-42 (2020)
Background & Aims Activation factor-1 transcription factor family members activating transcription factors 2 and 7 (ATF2 and ATF7) have highly redundant functions owing to highly homologous DNA binding sites. Their role in intestinal epithelial homeo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0605c14fb14b1dd6150625cf92552b65
https://doi.org/10.1016/j.jcmgh.2020.01.005
https://doi.org/10.1016/j.jcmgh.2020.01.005
Autor:
Pim J. Koelink, James C. Paton, Jonathan H. M. van der Meer, Wouter L. Smit, Gijs R. van den Brink, Ruben J. de Boer, Bartolomeus J. Meijer, Adrienne W. Paton, Jarom Heijmans, Jacqueline L.M. Vermeulen, Vanesa Muncan, Barbara F. Westendorp, Jun Qin, Evelien Dekker
Publikováno v:
Scientific reports, 11(1):9892. Nature Publishing Group
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Enforcing differentiation of cancer stem cells is considered as a potential strategy to sensitize colorectal cancer cells to irradiation and chemotherapy. Activation of the unfolded protein response, due to endoplasmic reticulum (ER) stress, causes r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224046a787934079d32021515ba0fffd
http://www.scopus.com/inward/record.url?scp=85105583312&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85105583312&partnerID=8YFLogxK
Epithelial argininosuccinate synthetase is dispensable for intestinal regeneration and tumorigenesis
Autor:
Evelien Dekker, Bartolomeus J. Meijer, Ruben J. de Boer, Manon van Roest, Pim J. Koelink, Lukas J. A. C. Hawinkels, Jonathan H. M. van der Meer, Sander Meisner, Vanesa Muncan, Theodorus B. M. Hakvoort, Wouter L. Smit, Gijs R. van den Brink, Jan Koster, Jarom Heijmans, Marja A. Boermeester, Eduard A. Struijs, Jacqueline L.M. Vermeulen
Publikováno v:
Cell death & disease, 12(10):897. Nature Publishing Group
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Cell Death & Disease
Cell Death and Disease, 12(10). SPRINGERNATURE
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Cell Death & Disease
Cell Death and Disease, 12(10). SPRINGERNATURE
The epithelial signaling pathways involved in damage and regeneration, and neoplastic transformation are known to be similar. We noted upregulation of argininosuccinate synthetase (ASS1) in hyperproliferative intestinal epithelium. Since ASS1 leads t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fe9f6b68e63ef2adef8188598cf44c
https://pure.amc.nl/en/publications/epithelial-argininosuccinate-synthetase-is-dispensable-for-intestinal-regeneration-and-tumorigenesis(b6498dad-bf3b-4e68-8c11-ffc21c53a4e0).html
https://pure.amc.nl/en/publications/epithelial-argininosuccinate-synthetase-is-dispensable-for-intestinal-regeneration-and-tumorigenesis(b6498dad-bf3b-4e68-8c11-ffc21c53a4e0).html
Autor:
Sandra N. Stapel, Heleen M. Oudemans-van Straaten, Armand R. J. Girbes, Patrick Thoral, Marc G. Vervloet, Ruben J de Boer
Publikováno v:
Stapel, S N, de Boer, R J, Thoral, P J, Vervloet, M G, Girbes, A R J & Oudemans-van Straaten, H M 2019, ' Amino Acid Loss during Continuous Venovenous Hemofiltration in Critically Ill Patients ', Blood Purification, vol. 48, no. 4, pp. 321-329 . https://doi.org/10.1159/000500998
Blood Purification, 48(4), 321-329. S. Karger AG
Blood purification, 48(4), 321-329. S. Karger AG
Blood Purification, 48(4), 321-329. S. Karger AG
Blood purification, 48(4), 321-329. S. Karger AG
Background/Objectives: During continuous venovenous hemofiltration (CVVH), there is unwanted loss of amino acids (AA) in the ultrafiltrate (UF). Solutes may also be removed by adsorption to the filter membrane. The aim was to quantify the total loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a806ec3d50afa2441ed682474cb64f
https://doi.org/10.1159/000500998
https://doi.org/10.1159/000500998
Autor:
Claudia N. Spaan, Jarom Heijmans, Jan Koster, Ruben J. de Boer, Alyson W. MacInnes, Jacqueline Ludovicus Maria Vermeulen, Wouter L. Smit, Gijs R. van den Brink, Tânia Martins Garcia, Jan Paul Medema, Marco Lezzerini, Vanesa Muncan, Prashanthi Ramesh, Bartolomeus J. Meijer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 117(41), 25560-25570. National Academy of Sciences
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Deregulated global mRNA translation is an emerging feature of cancer cells. Oncogenic transformation in colorectal cancer (CRC) is driven by mutations in APC, KRAS, SMAD4, and TP53, known as the adenoma-carcinoma sequence (ACS). Here we introduce eac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc285b42dbd5905f7bee76ae706c536
https://pure.amc.nl/en/publications/driver-mutations-of-the-adenomacarcinoma-sequence-govern-the-intestinal-epithelial-global-translational-capacity(b9887a9c-b0c1-49aa-bfe1-d01c5e5c2282).html
https://pure.amc.nl/en/publications/driver-mutations-of-the-adenomacarcinoma-sequence-govern-the-intestinal-epithelial-global-translational-capacity(b9887a9c-b0c1-49aa-bfe1-d01c5e5c2282).html