Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ruben Dyall"'
Publikováno v:
Science. 298:1797-1800
Major histocompatibility complex (mhc)–encoded molecules govern immune responses by presenting antigenic peptides to T cells. The extensive polymorphism of genes encoding these molecules is believed to enhance immune defense by broadening the array
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82f9c3c35f3dd2762f9e1b12de8ae5f
https://doi.org/10.1126/science.1076064
https://doi.org/10.1126/science.1076064
Autor:
Paul Szabo, Ilhem Messaoudi, Heather Potvin, Marc E. Weksler, Janko Nikolich-Zugich, Dragana Nikolich-Z̆ugich, Joel LeMaoult, John S. Manavalan, Ruben Dyall
Publikováno v:
The Journal of Immunology. 165:2367-2373
Relative diversity and representation of peripheral T cells bearing different TCR Vβ families are remarkably tightly regulated between birth and advanced adulthood. By contrast, individual elderly humans and C3H.SW and B10.BR aged mice display drast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff1200c6616d74a83f5da1b94945175
https://doi.org/10.4049/jimmunol.165.5.2367
https://doi.org/10.4049/jimmunol.165.5.2367
Autor:
Ruben Dyall, Roopa Srinivasan, Axel Hoos, Wilbur B. Bowne, Jedd D. Wolchok, William G. Hawkins, Jonathan J. Lewis, Alan N. Houghton, Jason S. Gold
Publikováno v:
Surgery. 128:273-280
Background: Xenogeneic DNA immunization can exploit small differences in expressed protein sequence resulting in immune recognition of self-molecules. We hypothesized that immunizing mice with xenogeneic DNA coding for the human melanosomal membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f688abcde5c08c16d9db21919675f1
https://doi.org/10.1067/msy.2000.107421
https://doi.org/10.1067/msy.2000.107421
Autor:
Jedd D. Wolchok, Ruben Dyall, Jonathan J. Lewis, Wilbur B. Bowne, Alan N. Houghton, William G. Hawkins, Roopa Srinivasan, Nathalie E. Blachere
Publikováno v:
The Journal of Experimental Medicine
Self-antigens, in the form of differentiation antigens, are commonly recognized by the immune system on melanoma and other cancers. We have shown previously that active immunization of mice against the melanocyte differentiation antigen, a tyrosinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15507643253bee527b3a2a05209e756e
http://europepmc.org/articles/PMC2195744
http://europepmc.org/articles/PMC2195744
Cellular requirements for the monoclonal antibody-mediated eradication of an established solid tumor
Publikováno v:
European Journal of Immunology. 29:30-37
Following subcutaneous implantation, the murine lymphoma E.G7 [a variant of EL-4, transfected with the chicken ovalbumin (OVA) gene] up-regulates the CD4 molecule. We previously showed that the administration of an anti-CD4 monoclonal antibody (mAb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c4aa2336e10f8b4a91216e711ff7554
https://doi.org/10.1002/(sici)1521-4141(199901)29:01<30::aid-immu30>3.0.co
https://doi.org/10.1002/(sici)1521-4141(199901)29:01<30::aid-immu30>3.0.co
Autor:
Paul Szabo, Jonathan J. Lewis, Lawrence W. Weber, Wilbur B. Bowne, Gregory Piskun, Janko Nikolić-Žugić, Yoichi Moroi, Ruben Dyall, Joel LeMaoult, Alan N. Houghton
Publikováno v:
The Journal of Experimental Medicine
In tumor transplantation models in mice, cytotoxic T lymphocytes (CTLs) are typically the primary effector cells. CTLs recognize major histocompatibility complex (MHC) class I–associated peptides expressed by tumors, leading to tumor rejection. Pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83aa1c650692b18b3163281a9669891
https://doi.org/10.1084/jem.188.9.1553
https://doi.org/10.1084/jem.188.9.1553
Autor:
J Nikolić-Zugić, Ruben Dyall
Publikováno v:
The Journal of Experimental Medicine
We have previously isolated, and characterized in vitro, two subsets of CD4hi T cell receptor (TCR)hi single positive (SP) thymocytes: CD8- and CD8lo. In this report, we have analyzed phenotypic, functional, and developmental characteristics of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf7c07de8ef7599de2b293156390596
http://europepmc.org/articles/PMC2191814
http://europepmc.org/articles/PMC2191814
Autor:
Manuel E. Engelhorn, Jason S. Gold, William G. Hawkins, Jonathan J. Lewis, José A. Guevara-Patiño, Cristina R. Ferrone, Jedd D. Wolchok, Ruben Dyall, Alan N. Houghton
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 170(10)
Successful active immunization against cancer requires induction of immunity against self or mutated self Ags. However, immunization against self Ags is difficult. Xenogeneic immunization with orthologous Ags induces cancer immunity. The present stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8b355c3a49db58ea881d30b97fbd87
https://pubmed.ncbi.nlm.nih.gov/12734366
https://pubmed.ncbi.nlm.nih.gov/12734366
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 164(4)
The murine class I molecule H-2Kb and its natural gene conversion variant, H-2Kbm8, which differs from H-2Kb solely at 4 aa at the bottom of the peptide-binding B pocket, are expressed in coisogenic mouse strains C57BL/6 (B6) and B6.C-H-2bm8 (bm8). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5eee2ca41a7d415f9d5e838c3889a0
https://pubmed.ncbi.nlm.nih.gov/10657612
https://pubmed.ncbi.nlm.nih.gov/10657612
Autor:
J Nikolić-Zugić, Ruben Dyall
Publikováno v:
The Journal of Experimental Medicine
The majority ( approximately 70%) of postselection CD4(+) single-positive (SP) thymocytes are CD8(lo)CD4(hi). These cells express very low levels of CD8, undetectable by flow cytofluorimetric (FCM) analysis, but sufficiently high to allow purificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83d38c70fec8253c20cb3e2a67f8a38
https://pubmed.ncbi.nlm.nih.gov/10499914
https://pubmed.ncbi.nlm.nih.gov/10499914