Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ruben, Tommasi"'
Autor:
Sujata M Bhavnani, Christopher M Rubino, Jeffrey P Hammel, Anthony P Cammarata, Kajal Larson, Kathryn Liolios, Sarah McLeod, Alita Miller, Paul G Ambrose, Ruben Tommasi, John O'Donnell
Publikováno v:
Open Forum Infectious Diseases. 9
Background SUL-DUR is a β-lactam/β-lactamase inhibitor combination in development for the treatment of ABC infections, which are often severe and associated with substantial mortality. PPK, PTA, and clinical PK/PD analyses were conducted using all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4d2a3d650c63780862254dacfb13767
https://doi.org/10.1093/ofid/ofac492.1896
https://doi.org/10.1093/ofid/ofac492.1896
Autor:
Gregory S. Basarab, Gunther H. Kern, John McNulty, John P. Mueller, Kenneth Lawrence, Karthick Vishwanathan, Richard A. Alm, Kevin Barvian, Peter Doig, Vincent Galullo, Humphrey Gardner, Madhusudhan Gowravaram, Michael Huband, Amy Kimzey, Marshall Morningstar, Amy Kutschke, Sushmita D. Lahiri, Manos Perros, Renu Singh, Virna J. A. Schuck, Ruben Tommasi, Grant Walkup, Joseph V. Newman
Publikováno v:
Scientific Reports. 5
With the diminishing effectiveness of current antibacterial therapies, it is critically important to discover agents that operate by a mechanism that circumvents existing resistance. ETX0914, the first of a new class of antibacterial agent targeted f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11eb8ed49d8c06158e0a890e6263e16b
https://doi.org/10.1038/srep14157
https://doi.org/10.1038/srep14157
Autor:
Michael D. Huband, Gunther Kern, Virna J A Schuck, John P. Mueller, Amy Kimzey, Peter Doig, Vincent Galullo, Richard A. Alm, Marshall L. Morningstar, Madhusudhan Gowravaram, John McNulty, Gregory S. Basarab, Kevin Barvian, Manos Perros, Karthick Vishwanathan, Ruben Tommasi, Amy Kutschke, Joseph V. Newman, Kenneth Lawrence, Humphrey Gardner, Grant K. Walkup, Renu Singh, Sushmita D. Lahiri
Publikováno v:
Scientific Reports
With the diminishing effectiveness of current antibacterial therapies, it is critically important to discover agents that operate by a mechanism that circumvents existing resistance. ETX0914, the first of a new class of antibacterial agent targeted f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f91f91194219ee0ffbba70c33475769
https://doi.org/10.1038/srep11827
https://doi.org/10.1038/srep11827
Publikováno v:
Nature reviews. Drug discovery. 14(8)
Antimicrobial drug resistance is a growing threat to global public health. Multidrug resistance among the 'ESKAPE' organisms - encompassing Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aerug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f7dcfe46e5b2211d808bc05e088c905
https://pubmed.ncbi.nlm.nih.gov/29192285
https://pubmed.ncbi.nlm.nih.gov/29192285
Publikováno v:
Journal of molecular graphicsmodelling. 30
Riboswitches are mRNA structural elements that act as intracellular sensors of small-molecule metabolites. By undergoing conformational changes capable of modulating translation or terminating transcription, riboswitches are able to play a role in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fefdd524997ad716a2af36b711b85c8e
https://pubmed.ncbi.nlm.nih.gov/21831681
https://pubmed.ncbi.nlm.nih.gov/21831681