Properdin produced by dendritic cells contributes to the activation of T cells

Autor: Essen, M.F. van, Schlagwein, N., Gijlswijk-Janssen, D.J. van, Ruben, J.M., Kooten, C. van, COMBAT Consortium

Publikováno v: Immunobiology, 227(4). ELSEVIER GMBH

The complement system does not only play an important role in the defence against microorganism and pathogens, but also contributes to the regulation of innate and adaptive immunity. Especially activation fragments C3a and C5a and complement activati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f041d1c39ca8cd3876ff015c079d1e28
https://hdl.handle.net/1887/3563169

Role of properdin in complement-mediated kidney diseases

Autor: Essen, M.F. van, Ruben, J.M., Vries, A.P.J. de, Kooten, C. van, Berger, S., Born, J. van den, Gros, P., Heuvel, L. van den, Kar, N. van de, Seelen, M., Vries, A. de, COMBAT Consortium

Publikováno v: Nephrology Dialysis Transplantation, 34(5), 742-750

As part of the innate immune system, the complement system is an important mechanism in our first line of defence, but it can also contribute to the onset of various diseases. In renal diseases, the dysregulation of the complement system is often cau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c2f2592698fd32a3935f6aa0f5194b
https://doi.org/10.1093/ndt/gfy233

Culture medium used during small interfering RNA (siRNA) transfection determines the maturation status of dendritic cells

Autor: Essen, M.F. van, Schlagwein, N., Gijlswijk-Janssen, D.J. van, Anholts, J.D.H., Eikmans, M., Ruben, J.M., Kooten, C. van, COMBAT Consortium

Publikováno v: Journal of Immunological Methods, 479. ELSEVIER

Gene silencing using small interfering ribonucleic acids (siRNA) is a powerful method to interfere with gene expression, allowing for the functional exploration of specific genes. siRNA interference can be applied in both cell lines, as well as in pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b1603fa1522810afff4e2a09d43f86
https://doi.org/10.1016/j.jim.2020.112748

Tumor-derived apoptotic bleb vaccines for the treatment of Acute Myeloid Leukemia

Autor: Ruben, J.M.

Publikováno v: Ruben, J M 2015, ' Tumor-derived apoptotic bleb vaccines for the treatment of Acute Myeloid Leukemia ', PhD, Vrije Universiteit Amsterdam .
Ruben, J M 2015, ' Tumor-derived apoptotic bleb vaccines for the treatment of Acute Myeloid Leukemia ', Doctor of Philosophy, VU University .

promotiedatum: 17-11-2015 � prom-id: 12868

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0e9cfb4b9e874504c571e7b5d039f768

CD1d-Restricted Antigen Presentation by V gamma 9V delta 2-T Cells Requires Trogocytosis

Autor: Schneiders, F.L., Prodohl, J., Ruben, J.M., O'Toole, T.G., Scheper, R.J., Bonneville, M., Scotet, E., Verheul, H.M.W., de Gruijl, T.D., van der Vliet, H.J.

Publikováno v: Cancer Immunology Research, 2(8), 732-740. American Association for Cancer Research Inc.
Schneiders, F L, Prodohl, J, Ruben, J M, O'Toole, T G, Scheper, R J, Bonneville, M, Scotet, E, Verheul, H M W, de Gruijl, T D & van der Vliet, H J 2014, ' CD1d-Restricted Antigen Presentation by V gamma 9V delta 2-T Cells Requires Trogocytosis ', Cancer Immunology Research, vol. 2, no. 8, pp. 732-740 . https://doi.org/10.1158/2326-6066.CIR-13-0167

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::29cf92a447a8574102781926f0f8c446
https://research.vumc.nl/en/publications/46334931-56d6-4ed7-81b0-42f919c3dcc6