Head-to-head comparison of leading blood tests for Alzheimer's disease pathology.

Autor: Schindler SE; Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA., Petersen KK; Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA., Saef B; Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA., Tosun D; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA., Shaw LM; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Zetterberg H; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; UK Dementia Research Institute Fluid Biomarkers Laboratory, UK DRI at UCL, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, Queen Square, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA., Dage JL; Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana, USA., Ferber K; Biogen, Biomarkers Group, Cambridge, Massachusetts, USA., Triana-Baltzer G; Neuroscience Biomarkers, Johnson and Johnson Innovative Medicine, San Diego, California, USA., Du-Cuny L; AbbVie, Ludwigshafen am Rhein, Rheinland-Pfalz, Germany., Li Y; Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA., Coomaraswamy J; Takeda Pharmaceutical Company Ltd., Cambridge, Massachusetts, USA., Baratta M; Takeda Pharmaceutical Company Ltd., Cambridge, Massachusetts, USA., Mordashova Y; AbbVie, Ludwigshafen am Rhein, Rheinland-Pfalz, Germany., Saad ZS; Neuroscience Biomarkers, Johnson and Johnson Innovative Medicine, San Diego, California, USA., Raunig DL; Takeda Pharmaceutical Company Ltd., Cambridge, Massachusetts, USA., Ashton NJ; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.; Banner Alzheimer's Institute, Phoenix, Arizona, USA.; Banner Sun Health Research Institute, Sun City, Arizona, USA., Meyers EA; Alzheimer's Association, Chicago, Illinois, USA., Rubel CE; Biogen, Biomarkers Group, Cambridge, Massachusetts, USA., Rosenbaugh EG; The Foundation for the National Institutes of Health, North Bethesda, Maryland, USA., Bannon AW; AbbVie, North Chicago, Illinois, USA., Potter WZ; Highly qualified expert, Philadelphia, Pennsylvania, USA.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Nov; Vol. 20 (11), pp. 8074-8096. Date of Electronic Publication: 2024 Oct 12.

Independent study demonstrates amyloid probability score accurately indicates amyloid pathology.

Autor: Fogelman I; C2N Diagnostics, St. Louis, Missouri, USA., West T; C2N Diagnostics, St. Louis, Missouri, USA., Braunstein JB; C2N Diagnostics, St. Louis, Missouri, USA., Verghese PB; C2N Diagnostics, St. Louis, Missouri, USA., Kirmess KM; C2N Diagnostics, St. Louis, Missouri, USA., Meyer MR; C2N Diagnostics, St. Louis, Missouri, USA., Contois JH; C2N Diagnostics, St. Louis, Missouri, USA., Shobin E; Biogen, Cambridge, Massachusetts, USA., Ferber KL; Biogen, Cambridge, Massachusetts, USA., Gagnon J; Biogen, Cambridge, Massachusetts, USA., Rubel CE; Biogen, Cambridge, Massachusetts, USA., Graham D; Biogen, Cambridge, Massachusetts, USA., Bateman RJ; Dept. of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Tracey Family SILQ Center, Washington University School of Medicine, St. Louis, Missouri, USA., Holtzman DM; Dept. of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Tracey Family SILQ Center, Washington University School of Medicine, St. Louis, Missouri, USA., Huang S; Stat4ward, Pittsburgh, Pennsylvania, USA., Yu J; Stat4ward, Pittsburgh, Pennsylvania, USA., Yang S; Stat4ward, Pittsburgh, Pennsylvania, USA., Yarasheski KE; C2N Diagnostics, St. Louis, Missouri, USA.

Publikováno v: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2023 May; Vol. 10 (5), pp. 765-778. Date of Electronic Publication: 2023 Mar 28.

Non-radiometric Cell-free Assay to Measure the Effect of Molecular Chaperones on AMP-activated Kinase Activity.

Autor: Wilson EB; McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Rubel CE; McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Schisler JC; McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Department of Pharmacology and Department of Pathology and Lab Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Publikováno v: Bio-protocol [Bio Protoc] 2019 Apr 20; Vol. 9 (8).

MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo.

Autor: Mattox TA; Department of Pharmacology, East Carolina University, Greenville, NC, USA., Young ME, Rubel CE, Spaniel C, Rodríguez JE, Grevengoed TJ, Gautel M, Xu Z, Anderson EJ, Willis MS

Publikováno v: Journal of bioenergetics and biomembranes [J Bioenerg Biomembr] 2014 Jun; Vol. 46 (3), pp. 173-87. Date of Electronic Publication: 2014 Apr 15.

Diggin' on u(biquitin): a novel method for the identification of physiological E3 ubiquitin ligase substrates.

Autor: Rubel CE; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7126, USA., Schisler JC, Hamlett ED, DeKroon RM, Gautel M, Alzate O, Patterson C

Publikováno v: Cell biochemistry and biophysics [Cell Biochem Biophys] 2013 Sep; Vol. 67 (1), pp. 127-38.