Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Rubaiyea"'
Autor:
Melkamu B. Tessema, Shouya Feng, Daniel Enosi Tuipulotu, Rubaiyea Farrukee, Chinh Ngo, Catarina Gago da Graça, Masahiro Yamomoto, Daniel T. Utzschneider, Andrew G. Brooks, Sarah L. Londrigan, Si Ming Man, Patrick C. Reading
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Dynamin-like GTPase proteins, including myxoma (Mx) and guanylate-binding proteins (GBPs), are among the many interferon stimulated genes induced following viral infections. While studies report that human (h)GBPs inhibit different viruses i
Externí odkaz:
https://doaj.org/article/ceb6b8a352e24988803a092b6ca91a95
Autor:
Rubaiyea Farrukee, Lara S. U. Schwab, James B. Barnes, Andrew G. Brooks, Sarah L. Londrigan, Gunther Hartmann, Thomas Zillinger, Patrick C. Reading
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Myxovirus resistance (Mx) proteins are products of interferon stimulated genes (ISGs) and Mx proteins of different species have been reported to mediate antiviral activity against a number of viruses, including influenza A viruses (IAV). Fer
Externí odkaz:
https://doaj.org/article/4f11a884256f454cb786cbb7c1250c09
Autor:
Lance R. Nigos, Nichollas E. Scott, Andrew G. Brooks, Malika Ait-Goughoulte, Sarah L. Londrigan, Patrick. C. Reading, Rubaiyea Farrukee
Publikováno v:
Pathogens, Vol 12, Iss 6, p 852 (2023)
Host cell restriction factors are intracellular proteins that can inhibit virus replication. Characterisation of novel host cell restriction factors can provide potential targets for host-directed therapies. In this study, we aimed to assess a member
Externí odkaz:
https://doaj.org/article/4b978ea391eb4398bcf315195a894686
Autor:
Fernando Villalón-Letelier, Rubaiyea Farrukee, Sarah L. Londrigan, Andrew G. Brooks, Patrick C. Reading
Publikováno v:
Viruses, Vol 14, Iss 11, p 2549 (2022)
MARCH1 and MARCH8 are closely related E3 ubiquitin ligases that ubiquitinate an overlapping spectrum of host proteins and restrict replication of certain viruses. While the antiviral activity of MARCH8 has been intensively studied, less is known rega
Externí odkaz:
https://doaj.org/article/d2799d011179478880f9458667599a39
Autor:
Leo Y Lee, Jie Zhou, Paulina Koszalka, Rebecca Frise, Rubaiyea Farrukee, Keiko Baba, Shahjahan Miah, Takao Shishido, Monica Galiano, Takashi Hashimoto, Shinya Omoto, Takeki Uehara, Edin J Mifsud, Neil Collinson, Klaus Kuhlbusch, Barry Clinch, Steffen Wildum, Wendy S Barclay, Aeron C Hurt
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009527 (2021)
Baloxavir is approved in several countries for the treatment of uncomplicated influenza in otherwise-healthy and high-risk patients. Treatment-emergent viruses with reduced susceptibility to baloxavir have been detected in clinical trials, but the li
Externí odkaz:
https://doaj.org/article/6a080755b2e74791b2fa666dd6d94232
Autor:
Rubaiyea Farrukee, Celeste Ming-Kay Tai, Ding Yuan Oh, Danielle E Anderson, Vithiagaran Gunalan, Martin Hibberd, Gary Yuk-Fai Lau, Ian G Barr, Veronika von Messling, Sebastian Maurer-Stroh, Aeron C Hurt
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008592 (2020)
The neuraminidase (NA) inhibitor (NAI) oseltamivir (OST) is the most widely used influenza antiviral drug. Several NA amino acid substitutions are reported to reduce viral susceptibility to OST in in vitro assays. However, whether there is a correlat
Externí odkaz:
https://doaj.org/article/8077b174301144968624520fb39ef22e
Autor:
Rubaiyea Farrukee, Malika Ait-Goughoulte, Philippa M. Saunders, Sarah L. Londrigan, Patrick C. Reading
Publikováno v:
Viruses, Vol 12, Iss 12, p 1381 (2020)
The paramyxo- and pneumovirus family includes a wide range of viruses that can cause respiratory and/or systemic infections in humans and animals. The significant disease burden of these viruses is further exacerbated by the limited therapeutics that
Externí odkaz:
https://doaj.org/article/470782d87773423f83d9e7d963e6b6b1
Akademický článek
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Akademický článek
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Autor:
Mifsud, Edin J.1,2, Farrukee, Rubaiyea2, Hurt, Aeron C.1, Reading, Patrick C.1,2, Barr, Ian G.1,2 Ian.Barr@influenzacentre.org
Publikováno v:
FEMS Microbes. 2022, Vol. 3, p1-8. 8p.