Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ruba Al Abdulla"'
Autor:
Sofia Lachiondo-Ortega, Claudia M. Rejano-Gordillo, Jorge Simon, Fernando Lopitz-Otsoa, Teresa C. Delgado, Krystyna Mazan-Mamczarz, Naroa Goikoetxea-Usandizaga, L. Estefanía Zapata-Pavas, Ana García-del Río, Pietro Guerra, Patricia Peña-Sanfélix, Natalia Hermán-Sánchez, Ruba Al-Abdulla, Carmen Fernandez-Rodríguez, Mikel Azkargorta, Alejandro Velázquez-Cruz, Joris Guyon, César Martín, Juan Diego Zalamea, Leire Egia-Mendikute, Arantza Sanz-Parra, Marina Serrano-Maciá, Irene González-Recio, Monika Gonzalez-Lopez, Luis Alfonso Martínez-Cruz, Patrizia Pontisso, Ana M. Aransay, Rosa Barrio, James D. Sutherland, Nicola G.A. Abrescia, Félix Elortza, Amaia Lujambio, Jesus M. Banales, Raúl M. Luque, Manuel D. Gahete, Asís Palazón, Matias A. Avila, Jose J. G. Marin, Supriyo De, Thomas Daubon, Antonio Díaz-Quintana, Irene Díaz-Moreno, Myriam Gorospe, Manuel S. Rodríguez, María Luz Martínez-Chantar
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113924- (2024)
Summary: The posttranslational modification of proteins critically influences many biological processes and is a key mechanism that regulates the function of the RNA-binding protein Hu antigen R (HuR), a hub in liver cancer. Here, we show that HuR is
Externí odkaz:
https://doaj.org/article/ac05448b67bf43d08eefd6737eb5e995
Autor:
Zeinab Waad Sadiq, Annamaria Brioli, Ruba Al-Abdulla, Gonca Çetin, Jacqueline Schütt, Hugo Murua Escobar, Elke Krüger, Frédéric Ebstein
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionProteasome inhibition is first line therapy in multiple myeloma (MM). The immunological potential of cell death triggered by defects of the ubiquitin-proteasome system (UPS) and subsequent perturbations of protein homeostasis is, however,
Externí odkaz:
https://doaj.org/article/44ee289e92e843e7a537f94d8279f0b3
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 724 (2023)
APN/CD13 is expressed in a variety of cells/tissues and is therefore associated with diverse physiological functions, including proliferation, differentiation, migration, angiogenesis, invasion, metastasis, vasoconstriction, and the regulation of nor
Externí odkaz:
https://doaj.org/article/32fc74fe931c4e20835940961ccff5e8
Autor:
Ruslan Al-Ali, Katharina Bauer, Jong-Whi Park, Ruba Al Abdulla, Valentina Fermi, Andreas von Deimling, Christel Herold-Mende, Jan-Philipp Mallm, Carl Herrmann, Wolfgang Wick, Şevin Turcan
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract The presence of genome-wide DNA hypermethylation is a hallmark of lower grade gliomas (LGG) with isocitrate dehydrogenase (IDH) mutations. Further molecular classification of IDH mutant gliomas is defined by the presence (IDHmut-codel) or ab
Externí odkaz:
https://doaj.org/article/648525fc70e5488fb89fa53efcf3aa6f
Autor:
Ruba Al-Abdulla, Hilda Ferrero, Talía Boronat-Belda, Sergi Soriano, Iván Quesada, Paloma Alonso-Magdalena
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1044
Humans are constantly exposed to many environmental pollutants, some of which have been largely acknowledged as key factors in the development of metabolic disorders such as diabetes and obesity. These chemicals have been classified as endocrine-disr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fa5cc9aebde922844ff2bfcf143c7c
Autor:
Ruba Al-Abdulla, Hilda Ferrero, Talía Boronat-Belda, Sergi Soriano, Iván Quesada, Paloma Alonso-Magdalena
Humans are constantly exposed to many environmental pollutants, some of which have been largely acknowledged as key factors in the development of metabolic disorders such as diabetes and obesity. These chemicals have been classified as endocrine-disr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38b040d2e79e730d95f906ee9f105063
https://doi.org/10.1101/2022.11.07.515444
https://doi.org/10.1101/2022.11.07.515444
Autor:
Jesper B. Andersen, María L. Martínez-Chantar, Matías A. Avila, Ruba Al-Abdulla, Laura Sanchez-Vicente, Colm J O'Rourke, Letizia Satriano, Rocio I.R. Macias, Maria J. Monte, Elisa Lozano, Sofía Del Carmen, Maitane Asensio, Jose J.G. Marin, Jesus M. Banales, Oscar Briz, Patricia Munoz-Garrido, Marta Alonso-Peña
Publikováno v:
Hepatology. 70:1246-1261
Although the multi-tyrosine kinase inhibitor sorafenib is useful in the treatment of several cancers, cholangiocarcinoma (CCA) is refractory to this drug. Among other mechanisms of chemoresistance, impaired uptake through human organic cation transpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c745e2a1c2d845892285d5c5bb8dc85a
https://doi.org/10.1002/hep.30656
https://doi.org/10.1002/hep.30656
Autor:
Jesper B. Andersen, Matías A. Avila, Jesus M. Banales, Maria A. Serrano, María L. Martínez-Chantar, Elisa Lozano, Rocio I.R. Macias, Ruba Al-Abdulla, Maria J. Monte, Colm J O'Rourke, Andreas Geier, Jose J.G. Marin, Oscar Briz
Publikováno v:
British Journal of Pharmacology. 176:787-800
Background and purpose The expression of the human organic cation transporter-1 (hOCT1, gene SLC22A1) is reduced in hepatocellular carcinoma (HCC). The molecular bases of this reduction and its relationship with the poor response of HCC to sorafenib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e486b49a1ac13eb44c258fa7d8f2b6f
https://doi.org/10.1111/bph.14563
https://doi.org/10.1111/bph.14563
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 8; Pages: 4182
RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)
RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)
Endocrine-disrupting chemicals (EDCs) are chemical substances that can interfere with the normal function of the endocrine system. EDCs are ubiquitous and can be found in a variety of consumer products such as food packaging materials, personal care
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880541d34ec6c3666646fa3d1d4e234f
https://doi.org/10.3390/ijms23084182
https://doi.org/10.3390/ijms23084182
Autor:
Wolfgang Wick, Ruslan Al-Ali, Jong-Whi Park, Valentina Fermi, Ruba Al Abdulla, Sevin Turcan, Andreas von Deimling, Katharina Bauer, Christel Herold-Mende, Jan-Philipp Mallm, Carl Herrmann
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
The presence of genome-wide DNA hypermethylation is a hallmark of lower grade gliomas (LGG) with isocitrate dehydrogenase (IDH) mutations. Further molecular classification of IDH mutant gliomas is defined by the presence (IDHmut-codel) or absence (ID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9988b8ec0ec46cce1bb48713b36d9bc
https://doi.org/10.1186/s40478-019-0851-y
https://doi.org/10.1186/s40478-019-0851-y