Potential Role of Circulating PD-L1+ Leukocytes as a Predictor of Response to Anti-PD-(L)1 Therapy in NSCLC Patients

Autor: Georgia Anguera, Maria Mulet, Carlos Zamora, Rubén Osuna-Gómez, Andrés Barba, Ivana Sullivan, Jorgina Serra-López, Elisabet Cantó, Silvia Vidal, Margarita Majem

Publikováno v: Biomedicines, Vol 12, Iss 5, p 958 (2024)

PD-(L)1 inhibitors are part of the treatment strategy for non-small cell lung cancer (NSCLC) although its efficacy is limited to certain patients. Our study aimed to identify patients who might benefit from anti-PD-(L)1 inhibitors by analyzing the PD

Externí odkaz: https://doaj.org/article/1743b63c341c4a9a946584a3e7e487fc

Impaired Regulation by IL-35 in Systemic Sclerosis

Autor: Vidal, Rubén Osuna-Gómez, Ivan Castellví, Maria Mulet, Mª Àngels Ortiz, Douglas E. Brough, Helen Sabzevari, Roshanak T. Semnani, Silvia

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10567

This study investigated the role of IL-35 in systemic sclerosis (SSc) patients, focusing on CD4+ T cell response and immunomodulatory cytokine production. By comparing the cytokine levels in healthy donors (HD) and SSc patients using ELISAs, we found

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::699bda299c5f393e2705d1a3b54ee439

Effector Mechanisms of CD8+ HLA-DR+ T Cells in Breast Cancer Patients Who Respond to Neoadjuvant Chemotherapy

Autor: Rubén Osuna-Gómez, Cristina Arqueros, Carla Galano, Maria Mulet, Carlos Zamora, Agustí Barnadas, Silvia Vidal

Publikováno v: Cancers, Vol 13, Iss 6167, p 6167 (2021)
Cancers; Volume 13; Issue 24; Pages: 6167
Cancers
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Universidad Europea (UEM)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

Simple Summary This study contributes to the characterization of CD8+ HLA-DR+ T cell mediated-mechanisms involved in the anti-tumor response in breast cancer patients who respond to neoadyuvant chemotherapy (NACT). Cultures with plasma from responder

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b022c438fa5994742f3b8add400dde5
https://www.mdpi.com/2072-6694/13/24/6167

Guest Editor's Introduction

Autor: Guerrero, Rubén Osuna, Naron, Stephen

Publikováno v: International Journal of Political Economy, 2000 Jul 01. 30(2), 3-6.

Externí odkaz: https://www.jstor.org/stable/40470770

Inside Orthodoxy.

Autor: Calleja, Emilio Díaz¹, Guerrero, Rubén Osuna²

Publikováno v: International Journal of Political Economy. Summer2000, Vol. 30 Issue 2, p7-34. 28p.