Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Rubén Marín-Juez"'
Autor:
Wanbin Hu, Shuxin Yang, Yasuhito Shimada, Magnus Münch, Rubén Marín-Juez, Annemarie H. Meijer, Herman P. Spaink
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-18 (2019)
Abstract Background The function of Toll-like receptor 2 (TLR2) in host defense against pathogens, especially Mycobacterium tuberculosis (Mtb) is poorly understood. To investigate the role of TLR2 during mycobacterial infection, we analyzed the respo
Externí odkaz:
https://doaj.org/article/fe7c1c672bc64583ab67559f360c0e55
Autor:
Sébastien Gauvrit, Alethia Villasenor, Boris Strilic, Philip Kitchen, Michelle M. Collins, Rubén Marín-Juez, Stefan Guenther, Hans-Martin Maischein, Nana Fukuda, Maurice A. Canham, Joshua M. Brickman, Clifford W. Bogue, Padma-Sheela Jayaraman, Didier Y. R. Stainier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
VEGFC, its receptor FLT4, and transcriptional effector PROX1 control formation of the lymphatic system but how is unclear. Here, the authors show that the transcription factor hematopoietically expressed homeobox (HHEX) regulates VEGFC, FLT4 and PROX
Externí odkaz:
https://doaj.org/article/3601d02f4c94462c8cb4148709279b67
Autor:
Claudia Gerri, Rubén Marín-Juez, Michele Marass, Alora Marks, Hans-Martin Maischein, Didier Y R. Stainier
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The molecular mechanism regulating macrophage interaction with endothelial cells during development is unclear. Here, the authors show that in zebrafish mutation of hypoxia-inducible factor-1α impairs macrophage mobilization from the aorta-gonad-mes
Externí odkaz:
https://doaj.org/article/ebd77d3a46e14354b42078d1b9cafcf1
Autor:
Dana Gancz, Brian C Raftrey, Gal Perlmoter, Rubén Marín-Juez, Jonathan Semo, Ryota L Matsuoka, Ravi Karra, Hila Raviv, Noga Moshe, Yoseph Addadi, Ofra Golani, Kenneth D Poss, Kristy Red-Horse, Didier YR Stainier, Karina Yaniv
Publikováno v:
eLife, Vol 8 (2019)
In recent years, there has been increasing interest in the role of lymphatics in organ repair and regeneration, due to their importance in immune surveillance and fluid homeostasis. Experimental approaches aimed at boosting lymphangiogenesis followin
Externí odkaz:
https://doaj.org/article/8723b2ae3cd64787ad7c55f1ed50a529
Autor:
Leonard Burg, Nicholas Palmer, Khrievono Kikhi, Evgeniya S Miroshnik, Helen Rueckert, Eleanor Gaddy, Carlee MacPherson Cunningham, Kenny Mattonet, Shih-Lei Lai, Rubén Marín-Juez, Richard B Waring, Didier Y R Stainier, Darius Balciunas
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007754 (2018)
Many eukaryotic genes play essential roles in multiple biological processes in several different tissues. Conditional mutants are needed to analyze genes with such pleiotropic functions. In vertebrates, conditional gene inactivation has only been fea
Externí odkaz:
https://doaj.org/article/d9b121ce093d49f58fafc9f4ea33ac06
Autor:
Srdjan Boskovic, Rubén Marín-Juez, Jovana Jasnic, Sven Reischauer, Hadil El Sammak, Ana Kojic, Georgine Faulkner, Dragica Radojkovic, Didier Y R Stainier, Snezana Kojic
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204312 (2018)
Muscle proteins with ankyrin repeats (MARPs) ANKRD1 and ANKRD2 are titin-associated proteins with a putative role as transcriptional co-regulators in striated muscle, involved in the cellular response to mechanical, oxidative and metabolic stress. Si
Externí odkaz:
https://doaj.org/article/b80eb1c1057948418ac69033ce7cb8f8
Autor:
Shih-Lei Lai, Rubén Marín-Juez, Pedro Luís Moura, Carsten Kuenne, Jason Kuan Han Lai, Ayele Taddese Tsedeke, Stefan Guenther, Mario Looso, Didier YR Stainier
Publikováno v:
eLife, Vol 6 (2017)
Zebrafish display a distinct ability to regenerate their heart following injury. However, this ability is not shared by another teleost, the medaka. In order to identify cellular and molecular bases for this difference, we performed comparative trans
Externí odkaz:
https://doaj.org/article/a10edc72293144be886a42492f092c6f
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
[This corrects the article DOI: 10.1371/journal.pone.0080628.].
Externí odkaz:
https://doaj.org/article/d17486956d214867ad10f5ac74e49049
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80628 (2013)
The glucose transporter 4 (GLUT4) plays a key role in glucose uptake in insulin target tissues. This transporter has been extensively studied in many species in terms of its function, expression and cellular traffic and complex mechanisms are involve
Externí odkaz:
https://doaj.org/article/b63558d8b2844362a691fb58aea1e79a
Autor:
Hadil El-Sammak, Bingyuan Yang, Stefan Guenther, Wenbiao Chen, Rubén Marín-Juez, Didier Y.R. Stainier
Publikováno v:
Circ Res
Background: Ischemic heart disease following the obstruction of coronary vessels leads to the death of cardiac tissue and the formation of a fibrotic scar. In contrast to adult mammals, zebrafish can regenerate their heart after injury, enabling the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132e2ace340ef0af0988760980f63fc8
https://doi.org/10.1161/circresaha.121.319929
https://doi.org/10.1161/circresaha.121.319929