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pro vyhledávání: '"Rubén López-Blanco"'
Autor:
Rubén López-Blanco, Beatriz Rodríguez-Bayona, Eloisa Andújar, José A. Brieva, Antonio Campos-Caro, Ana Ramos-Amaya, Mónica Pérez-Alegre
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 194(3)
Human circulating Ag-induced plasma cells (PCs) contain a high proportion of cycling cells. This study reveals that these PCs spontaneously proliferate in culture during 72 h, as determined by BrdU-uptake detection. Transcriptome analysis indicates t
Autor:
Beatriz Rodríguez-Bayona, Ana Ramos-Amaya, Antonio Campos-Caro, Rubén López-Blanco, José A. Brieva
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 191(10)
Maturation and survival of plasma cells (PCs) depends on extrinsic factors provided in specialized niches. In addition, B lymphocyte differentiation into PCs requires the activation of the JAK–STAT-3 pathway. However, whether STAT-3 is needed only