Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Rubén Gómez Sánchez"'
En los últimos años, la oferta y demanda de los cursos a distancia ha presentado un incremento notorio. Las instituciones educativas con mayor posición económica ofrecen cursos o formación a distancia en todos los niveles (grados y posgrados), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064df26241e08fc5d0dc8a4d1130d214
La presencia tecnológica es actualmente un proceso patente en todo el mundo, e involucra a diversos ámbitos, entre ellos el educativo. Por esa razón es fundamental que los agentes participantes se relacionen con ella y la dominen, a fin de consegu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e73d032a8a616c14c292414751d7a6d
Autor:
Jana Sánchez-Wandelmer, Franziska Kriegenburg, Sabrina Rohringer, Martina Schuschnig, Rubén Gómez-Sánchez, Bettina Zens, Susana Abreu, Ralph Hardenberg, David Hollenstein, Jieqiong Gao, Christian Ungermann, Sascha Martens, Claudine Kraft, Fulvio Reggiori
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
The protease Atg4 mediates Atg8 lipidation, required for autophagosome biogenesis, but also triggers Atg8 release from the membranes, however is unclear how these steps are coordinated. Here the authors show that phosphorylation by Atg1 inhibits Atg4
Externí odkaz:
https://doaj.org/article/0d25d8e1163b4f90ae02c9c439b13fba
Autor:
Wondwossen M Yeshaw, Marianne van der Zwaag, Francesco Pinto, Liza L Lahaye, Anita IE Faber, Rubén Gómez-Sánchez, Amalia M Dolga, Conor Poland, Anthony P Monaco, Sven CD van IJzendoorn, Nicola A Grzeschik, Antonio Velayos-Baeza, Ody CM Sibon
Publikováno v:
eLife, Vol 8 (2019)
The VPS13A gene is associated with the neurodegenerative disorder Chorea Acanthocytosis. It is unknown what the consequences are of impaired function of VPS13A at the subcellular level. We demonstrate that VPS13A is a peripheral membrane protein, ass
Externí odkaz:
https://doaj.org/article/82c95e0d7eb64c9cabeaa87ffdcdcbf4
Autor:
Rubén Gómez-Sánchez, Sokhna M.S. Yakhine-Diop, Mario Rodríguez-Arribas, José M. Bravo-San Pedro, Guadalupe Martínez-Chacón, Elisabet Uribe-Carretero, Diana C.J. Pinheiro de Castro, Elisa Pizarro-Estrella, José M. Fuentes, Rosa A. González-Polo
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 641-647 (2016)
We characterized the dynamics of autophagy in vitro using four different cell systems and analyzing markers widely used in this field, i.e. LC3 (microtubule-associated protein 1 light chain 3; protein recruited from the cytosol (LC3-I) to the autopha
Externí odkaz:
https://doaj.org/article/e738a00b7f0e49c5aa8737fa383aad0d
Autor:
Sokhna M. S. Yakhine-Diop, Mario Rodríguez-Arribas, Guadalupe Martínez-Chacón, Elisabet Uribe-Carretero, Rubén Gómez-Sánchez, Ana Aiastui, Adolfo López de Munain, José M. Bravo-San Pedro, Mireia Niso-Santano, Rosa A. González-Polo, José M. Fuentes
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Parkinson's disease (PD) is a multifactorial neurodegenerative disorder. The pathogenesis of this disease is associated with gene and environmental factors. Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most frequent genetic cause of fami
Externí odkaz:
https://doaj.org/article/9072bebe520e440198e2daff04c1bf4f
Publikováno v:
Current Opinion in Cell Biology. 71:112-119
The de novo generation of double-membrane autophagosomes is the hallmark of autophagy. The initial membranous precursor cisterna, the phagophore, is very likely generated by the fusion of vesicles and acts as a membrane seed for the subsequent expans
Autor:
Rubén Gómez-Sánchez, Matthew E. Gegg, José M. Bravo-San Pedro, Mireia Niso-Santano, Lydia Alvarez-Erviti, Elisa Pizarro-Estrella, Yolanda Gutiérrez-Martín, Alberto Alvarez-Barrientos, José M. Fuentes, Rosa Ana González-Polo, Anthony H.V. Schapira
Publikováno v:
Neurobiology of Disease, Vol 62, Iss , Pp 426-440 (2014)
Mutations of the PTEN-induced kinase 1 (PINK1) gene are a cause of autosomal recessive Parkinson's disease (PD). This gene encodes a mitochondrial serine/threonine kinase, which is partly localized to mitochondria, and has been shown to play a role i
Externí odkaz:
https://doaj.org/article/bff03490c510442b98a7dee320375096
Autor:
Rubén Gómez-Sánchez, José M. Bravo-San Pedro, Matthew E. Gegg, Rosa A. González-Polo, José M. Fuentes
Publikováno v:
Parkinson's Disease, Vol 2016 (2016)
Externí odkaz:
https://doaj.org/article/aeaac44242ec41efa6439cc2cbc2c1d6
Publikováno v:
Revista de Ciencia e Investigación en Defensa-CAEN; Vol. 2 No. 3 (2021): Vol 2, N° 3, Octubre 2021-Enero 2022; 49-65
Revista de Ciencia e Investigación en Defensa-CAEN; Vol. 2 Núm. 3 (2021): Vol 2, N° 3, Octubre 2021-Enero 2022; 49-65
Revista de Ciencia e Investigación en Defensa
Centro de Altos Estudios Nacionales
instacron:CAEN
Revista de Ciencia e Investigación en Defensa-CAEN; Vol. 2 Núm. 3 (2021): Vol 2, N° 3, Octubre 2021-Enero 2022; 49-65
Revista de Ciencia e Investigación en Defensa
Centro de Altos Estudios Nacionales
instacron:CAEN
The results achieved by Singapore in terms oflevels of development are recognized by differentInternational organizations. Recently, WordEconomic Forum (2019) published its global report oncompetitiveness noting that Singapore has surpassedto many co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e1032205e72d4c8a8f4f970f35fd2b
https://www.recide.caen.edu.pe/index.php/recide/article/view/64
https://www.recide.caen.edu.pe/index.php/recide/article/view/64