Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia‐Inducible Factor 1‐α (HIF1‐α) in an Ovine Model of Acute Myocardial Infarction

Autor: Anna P. Hnatiuk, Sang‐Ging Ong, Fernanda D. Olea, Paola Locatelli, Johannes Riegler, Won Hee Lee, Cheng Hao Jen, Andrea De Lorenzi, Carlos S. Giménez, Rubén Laguens, Joseph C. Wu, Alberto Crottogini

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 7 (2016)

BackgroundBone marrow mesenchymal stromal cells (BMMSCs) are cardioprotective in acute myocardial infarction (AMI) because of release of paracrine angiogenic and prosurvival factors. Hypoxia‐inducible factor 1‐α (HIF1‐α), rapidly degraded dur

Externí odkaz: https://doaj.org/article/0751544adff642cba976537dc3a450d8

Presence of antigen-experienced T cells with low grade of differentiation and proliferative potential in chronic Chagas disease myocarditis.

Autor: Rafael J Argüello, Carlos Vigliano, Patricia Cabeza-Meckert, Rodolfo Viotti, Fernando Garelli, Liliana E Favaloro, Roberto R Favaloro, Rubén Laguens, Susana A Laucella

Publikováno v: PLoS Neglected Tropical Diseases, Vol 8, Iss 8, p e2989 (2014)

The main consequence of chronic Trypanosoma cruzi infection is the development of myocarditis in approximately 20-30% of infected individuals but not until 10-20 years after the initial infection. We have previously shown that circulating interferon-

Externí odkaz: https://doaj.org/article/f1d5cae3887c49b48ee9e7380804b366

Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia‐Inducible Factor 1‐α (HIF1‐α) in an Ovine Model of Acute Myocardial Infarction

Autor: Won Hee Lee, Joseph C. Wu, Anna Hnatiuk, Andrea De Lorenzi, Rubén Laguens, Johannes Riegler, Sang-Ging Ong, Paola Locatelli, Alberto J. Crottogini, Carlos Sebastián Giménez, Cheng Hao Jen, Fernanda Daniela Olea

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
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Consejo Nacional de Investigaciones Científicas y Técnicas
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Background Bone marrow mesenchymal stromal cells ( BMMSC s) are cardioprotective in acute myocardial infarction ( AMI ) because of release of paracrine angiogenic and prosurvival factors. Hypoxia‐inducible factor 1‐α ( HIF 1‐α), rapidly degra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cccec05a17236a17670e61cbdcd0906
http://europepmc.org/articles/PMC5015403

Presencia de placas coronarias vulnerables en mujeres de mediana edad que sufrieron muerte cerebral

Autor: Enrique Gurfinkel, Carlos Vigliano, Patricia Cabeza Meckert, Alejandro Bertolotti, Roberto Favaloro, Juan Carlos Troncoso, Rubén Laguens

Publikováno v: Revista Argentina de Cardiología, Vol 77, Iss 6, Pp 478-486 (2009)

RESUMENIntroducciónLas placas vulnerables de las arterias coronarias se encuentran habitualmente en varonessin sintomatología previa que fallecieron súbitamente o debido a un síndrome coronarioagudo. La frecuencia y las características de estas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::e9a0853d41001d5d4b199a4ee0771d0c
http://www.sac.org.ar/web_files/download/revista_articulos/files/v77n6a8-pdf-1735.pdf

The c-myc activation in cervical carcinomas and HPV 16 infections

Autor: Carlos Daniel Golijow, Fernando Noel Dulout, Rubén Laguens, Martín Carlos Abba

Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 557:151-158

Despite the prominent role for Human Papillomavirus (HPV) infection in the development of genital cancer, other genetic or environmental co-factors have also been involved. Studies of c-myc activation in cervical carcinomas have reported that gene ov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3743f8df9ff50d8e378aef0b724ab643
https://doi.org/10.1016/j.mrgentox.2003.10.005