Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ruaidhrí P. Kirwan"'
Publikováno v:
Journal of Glaucoma. 13:327-334
Extensive remodeling of the lamina cribrosa extracellular matrix occurs in primary open angle glaucoma. The transforming growth factor-beta (TGF-beta) and matrix metalloproteinase (MMP) protein families are implicated in this process. The authors inv
Publikováno v:
Investigative ophthalmologyvisual science. 53(4)
Purpose Vascular hypoperfusion, extracellular matrix remodeling and axon loss are pathological characteristics of the glaucomatous optic nerve head. We report a novel study demonstrating transcriptional responses in optic nerve lamina cribrosa (LC) c
Publikováno v:
Molecular Vision
Purpose Marked extracellular matrix (ECM) remodeling occurs in the human optic nerve head in primary open angle glaucoma (POAG). The glial fibrillary acid protein (GFAP) negative lamina cribrosa cell may play an important role in this remodeling proc
Autor:
Ruaidhrí P, Kirwan, Cecilia H, Fenerty, John, Crean, Robert J, Wordinger, Abbot F, Clark, Colm J, O'Brien
Publikováno v:
Molecular vision. 11
The mechanical effect of raised intraocular pressure is a recognised stimulus for optic neuropathy in primary open angle glaucoma (POAG). Characteristic extracellular matrix (ECM) remodelling accompanies axonal damage in the lamina cribrosa (LC) of t
Publikováno v:
Glia. 52(4)
Primary open-angle glaucoma (POAG) is a progressive optic neuropathy, which is a major cause of worldwide visual impairment and blindness. Pathological hallmarks of the glaucomatous optic nerve head (ONH) include retinal ganglion cell axon loss and e
Publikováno v:
Annals of Pharmacotherapy. 41:161-162
Autor:
Abbot F. Clark, Ruaidhrí P. Kirwan, John Crean, Colm O'Brien, Robert J. Wordinger, C.H. Fenerty
Publikováno v:
Journal of Biomechanics. 39:S384-S385
Autor:
Ruaidhrí P Kirwan
Publikováno v:
Journal of Glaucoma; Aug2004, Vol. 13 Issue 4, p327-334, 8p
Publikováno v:
Glia; Dec2005, Vol. 52 Issue 4, p309-324, 0p