Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ru-Yan Zhang"'
Autor:
Xiao-Ran Liu, Jian-Jun Yu, Guo-Hong Song, Li-Jun Di, Han-Fang Jiang, Ying Yan, Xu Liang, Ru-Yan Zhang, Ran Ran, Jing Wang, Han Bai, Shi-Dong Jia, Hui-Ping Li
Publikováno v:
Breast, Vol 55, Iss , Pp 7-15 (2021)
Background: The role of peripheral blood lymphocyte (pBL) in breast cancer has long been studied. However, the predictive role of pBL in advanced breast cancer (ABC) is poorly understood. Methods: A total of 303 patients with ABC were consecutively r
Externí odkaz:
https://doaj.org/article/b4f0144068fe4f4eb7a67d9a0f3408c6
Autor:
Shi-Hao Zhou, Yu-Ting Li, Ru-Yan Zhang, Yan-Ling Liu, Zi-Wei You, Miao-Miao Bian, Yu Wen, Jian Wang, Jing-Jing Du, Jun Guo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The tumor-associated antigen mucin 1 (MUC1) is an attractive target of antitumor vaccine, but its weak immunogenicity is a big challenge for the development of vaccine. In order to enhance immune responses against MUC1, herein, we conjugated small mo
Externí odkaz:
https://doaj.org/article/0517683d82744606ac67b555f04e1829
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Mucin 1 (MUC1), a well-known tumor-associated antigen and attractive target for tumor immunotherapy, is overexpressed in most human epithelial adenomas with aberrant glycosylation. However, its low immunogenicity impedes the development of MUC1-targe
Externí odkaz:
https://doaj.org/article/d27accaeee4643ec905d356559f76d60
Autor:
Xiao-ran Liu PhD, Ru-yan Zhang MD, Hao Gong PhD, Hope S. Rugo MD, Ling-bo Chen PhD, Yuan Fu PhD, Jian-wei Che PhD, Jian Tie MD, Bin Shao MD, Feng-ling Wan, Wei-yao Kong MBBS, Guo-hong Song MD, Han-fang Jiang MD, Guo-bing Xu MD, Hui-ping Li MD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 19 (2020)
Background: More than 30% of estrogen receptor-positive breast cancers are resistant to primary hormone therapy, and about 40% that initially respond to hormone therapy eventually acquire resistance. Although the mechanisms of hormone therapy resista
Externí odkaz:
https://doaj.org/article/e592ea94349f454a833b411628097897
Autor:
Ru-Yan Zhang, Shi-Hao Zhou, Ran-Ran Feng, Yu Wen, Dong Ding, Zhi-Ming Zhang, Hua-Wei Wei, Jun Guo
Publikováno v:
ACS Chemical Biology. 18:915-923
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aaa02670688bc6610540eed070152bb
https://doi.org/10.1021/acschembio.3c00050
https://doi.org/10.1021/acschembio.3c00050
Novel sialoglycan linkage for constructing adjuvant-protein conjugate as potent vaccine for COVID-19
Autor:
Yu Wen, Ru-Yan Zhang, Jian Wang, Shi-Hao Zhou, Xiao-Qian Peng, Dong Ding, Zhi-Ming Zhang, Hua-Wei Wei, Jun Guo
Publikováno v:
Journal of Controlled Release. 355:238-247
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcfa0c4b9c1c05a7faf6b42f430c5f43
https://doi.org/10.1016/j.jconrel.2023.01.062
https://doi.org/10.1016/j.jconrel.2023.01.062
Autor:
Shi-Hao Zhou, Ru-Yan Zhang, Zi-Wei You, Yong-Ke Zou, Yu Wen, Jian Wang, Dong Ding, Miao-Miao Bian, Zhi-Ming Zhang, Hong Yuan, Guang-Fu Yang, Jun Guo
Publikováno v:
ACS Applied Materials & Interfaces. 15:8914-8926
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a5a7d1a01bb7ceded72f5a7624ea84c
https://doi.org/10.1021/acsami.2c19736
https://doi.org/10.1021/acsami.2c19736
Autor:
Dong Ding, Yu Wen, Chun-Miao Liao, Xu-Guang Yin, Ru-Yan Zhang, Jian Wang, Shi-Hao Zhou, Zhi-Ming Zhang, Yong-Ke Zou, Xiao-Fei Gao, Hua-Wei Wei, Guang-Fu Yang, Jun Guo
Publikováno v:
Journal of Medicinal Chemistry. 66:1467-1483
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04614a23b1391ae0aa291c6283de21c5
https://doi.org/10.1021/acs.jmedchem.2c01642
https://doi.org/10.1021/acs.jmedchem.2c01642
Autor:
Ru-Yan Zhang, Shi-Hao Zhou, Chen-Bin He, Jian Wang, Yu Wen, Ran-Ran Feng, Xu-Guang Yin, Guang-Fu Yang, Jun Guo
Publikováno v:
ACS Infectious Diseases. 8:1367-1375
With the global pandemic of the new coronavirus disease (COVID-19), a safe, effective, and affordable mass-produced vaccine remains the current focus of research. Herein, we designed an adjuvant-protein conjugate vaccine candidate, in which the TLR7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62cfa52e09684a47e92fd441eb451118
https://doi.org/10.1021/acsinfecdis.2c00259
https://doi.org/10.1021/acsinfecdis.2c00259
Autor:
Jian Wang, Xu-Guang Yin, Yu Wen, Jie Lu, Ru-Yan Zhang, Shi-Hao Zhou, Chun-Miao Liao, Hua-Wei Wei, Jun Guo
Publikováno v:
Journal of Medicinal Chemistry. 65:3563-3574
Safe and effective vaccines are the best method to defeat worldwide SARS-CoV-2 and its circulating variants. The SARS-CoV-2 S protein and its subunits are the most attractive targets for the development of protein-based vaccines. In this study, we ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521758f8fbc57ab21c8a06a0da65f289
https://doi.org/10.1021/acs.jmedchem.1c02025
https://doi.org/10.1021/acs.jmedchem.1c02025