Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ru-Jia Zhao"'
Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2
Autor:
Qing-Tao He, Peng Xiao, Shen-Ming Huang, Ying-Li Jia, Zhong-Liang Zhu, Jing-Yu Lin, Fan Yang, Xiao-Na Tao, Ru-Jia Zhao, Feng-Yuan Gao, Xiao-Gang Niu, Kun-Hong Xiao, Jiangyun Wang, Changwen Jin, Jin-Peng Sun, Xiao Yu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The interaction between a GPCR, such as the vasopressin receptor-2 (V2R), and arrestin depends on the receptors’ phosphorylation pattern. Here authors use FRET and NMR to analyze the phosphorylation patterns of the V2R-arrestin complex and show tha
Externí odkaz:
https://doaj.org/article/5ffe1d9ce0c04791b889a4c6d158110f
Autor:
Hui Lin, Peng Xiao, Rui-Qian Bu, Shengchao Guo, Zhao Yang, Daopeng Yuan, Zhong-Liang Zhu, Chuan-Xin Zhang, Qing-Tao He, Chao Zhang, Yu-Qi Ping, Ru-Jia Zhao, Chuan-Shun Ma, Chang-Hao Liu, Xiao-Ning Zhang, Dan Jiang, Shaohui Huang, Yue-Tong Xi, Dao-Lai Zhang, Chen-Yang Xue, Bai-Sheng Yang, Jian-Yuan Li, Hao-Cheng Lin, Xu-Hui Zeng, Han Zhao, Wen-Ming Xu, Fan Yi, Zhongmin Liu, Jin-Peng Sun, Xiao Yu
Publikováno v:
Nature Chemical Biology. 18:1196-1203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b4731d217e1c6493f1433b86a842ba9
https://doi.org/10.1038/s41589-022-01084-6
https://doi.org/10.1038/s41589-022-01084-6
Autor:
Yu-Qi Ping, Peng Xiao, Fan Yang, Ru-Jia Zhao, Sheng-Chao Guo, Xu Yan, Xiang Wu, Chao Zhang, Yan Lu, Fenghui Zhao, Fulai Zhou, Yue-Tong Xi, Wanchao Yin, Feng-Zhen Liu, Dong-Fang He, Dao-Lai Zhang, Zhong-Liang Zhu, Yi Jiang, Lutao Du, Shi-Qing Feng, Torsten Schöneberg, Ines Liebscher, H. Eric Xu, Jin-Peng Sun
Publikováno v:
Nature. 604:763-770
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35b6eb7dd35847537495680bf901b423
https://doi.org/10.1038/s41586-022-04619-y
https://doi.org/10.1038/s41586-022-04619-y
Autor:
Qingya Shen, Xiaona Tao, Ya-Ni Zhong, Zijian Li, Xin Wen, Caiping Tian, Huibing Zhang, Jin-Peng Sun, Fan Yang, Fan Yi, H. Eric Xu, Xiao Yu, Yi Jiang, Peng Xiao, Guang-Yu Wang, Yan Zhang, Wen-Tao An, Shaolong Li, Changxiu Qu, Zhao Yang, Chunyou Mao, Ru-Jia Zhao, Yu-Qi Ping, Jing Yang, Dan-Dan Shen
Publikováno v:
Nature. 589:620-626
Adhesion G-protein-coupled receptors (GPCRs) are a major family of GPCRs, but limited knowledge of their ligand regulation or structure is available1-3. Here we report that glucocorticoid stress hormones activate adhesion G-protein-coupled receptor G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e2ed5882cb6f1d557e1bfe7972e054a
https://doi.org/10.1038/s41586-020-03083-w
https://doi.org/10.1038/s41586-020-03083-w
Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2
Autor:
Shen-Ming Huang, Peng Xiao, Changwen Jin, Zhongliang Zhu, Ru-Jia Zhao, Xiaogang Niu, Jing-Yu Lin, Qing-Tao He, Kunhong Xiao, Xiaona Tao, Fan Yang, Jiangyun Wang, Xiao Yu, Feng-Yuan Gao, Jin-Peng Sun, Yingli Jia
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Arrestins recognize different receptor phosphorylation patterns and convert this information to selective arrestin functions to expand the functional diversity of the G protein-coupled receptor (GPCR) superfamilies. However, the principles governing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567cecf2cf5067f8f9030e37f04c7209
https://doi.org/10.1038/s41467-021-22731-x
https://doi.org/10.1038/s41467-021-22731-x
Autor:
Ya-Ni Zhong, Xiaona Tao, Xu Yan, Jin-Peng Sun, Qingya Shen, Xiao Yu, Changxiu Qu, Dan-Dan Shen, Ying Guan, Chao Zhang, Chunyou Mao, Peng-Ju Zhang, Ru-Jia Zhao, Peng Xiao, Guige Hou, Yan Zhang, Guihua Hou, Junyan He, Fan Yang, Huibing Zhang, Renjie Chai, You-Fei Guan, Zijian Li
Publikováno v:
Science Advances. 7
Selective modulation of the heterotrimeric G protein α S subunit-coupled prostaglandin E2 (PGE2) receptor EP2 subtype is a promising therapeutic strategy for osteoporosis, ocular hypertension, neurodegenerative diseases, and cardiovascular disorders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3065f9943bdd4eea5ddf8dc5e5152bac
https://doi.org/10.1126/sciadv.abf1268
https://doi.org/10.1126/sciadv.abf1268
Autor:
Changxiu, Qu, Chunyou, Mao, Peng, Xiao, Qingya, Shen, Ya-Ni, Zhong, Fan, Yang, Dan-Dan, Shen, Xiaona, Tao, Huibing, Zhang, Xu, Yan, Ru-Jia, Zhao, Junyan, He, Ying, Guan, Chao, Zhang, Guihua, Hou, Peng-Ju, Zhang, Guige, Hou, Zijian, Li, Xiao, Yu, Ren-Jie, Chai, You-Fei, Guan, Jin-Peng, Sun, Yan, Zhang
Publikováno v:
Science advances. 7(14)
Selective modulation of the heterotrimeric G protein α S subunit-coupled prostaglandin E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::61b1b0a266e60b5b6041479348428579
https://pubmed.ncbi.nlm.nih.gov/33811074
https://pubmed.ncbi.nlm.nih.gov/33811074
Autor:
Yu-Qi, Ping, Chunyou, Mao, Peng, Xiao, Ru-Jia, Zhao, Yi, Jiang, Zhao, Yang, Wen-Tao, An, Dan-Dan, Shen, Fan, Yang, Huibing, Zhang, Changxiu, Qu, Qingya, Shen, Caiping, Tian, Zi-Jian, Li, Shaolong, Li, Guang-Yu, Wang, Xiaona, Tao, Xin, Wen, Ya-Ni, Zhong, Jing, Yang, Fan, Yi, Xiao, Yu, H Eric, Xu, Yan, Zhang, Jin-Peng, Sun
Publikováno v:
Nature. 589(7843)
Adhesion G-protein-coupled receptors (GPCRs) are a major family of GPCRs, but limited knowledge of their ligand regulation or structure is available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3904457e1c865233edee4d1eb72d63f4
https://pubmed.ncbi.nlm.nih.gov/33408414
https://pubmed.ncbi.nlm.nih.gov/33408414