Zobrazeno 1 - 10
of 465
pro vyhledávání: '"Ru Xiao"'
Autor:
Cheng Wang, Ru Xiao, Qingbo Yang, Jiaoyang Pan, Pengfei Cui, Shuwen Zhou, Lin Qiu, Yajing Zhang, Jianhao Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 171, Iss , Pp 116175- (2024)
Bacterial infections are a significant global health concern, particularly in the context of skin infections and chronic wounds, which was further exacerbated by the emerging of antibiotic resistance. Therefore, there are urgent needs to develop alte
Externí odkaz:
https://doaj.org/article/82e9177d56104ddbb1e06e70108f929e
Autor:
Ruogu Xu, Shengjun Xu, Fei Wang, Ru Xiao, Pei Tang, Xiaoyin Zhang, Shuo Bai, Zhenhua Sun, Feng Li
Publikováno v:
Small Structures, Vol 4, Iss 3, Pp n/a-n/a (2023)
Poly(ethylene oxide) (PEO) is among the most promising candidates for solid‐state electrolytes in lithium metal batteries. However, the low ionic conductivity caused by strong coordination between Li ions and the EO chains limits the practical appl
Externí odkaz:
https://doaj.org/article/3f9460fd28a84a6b87b9d7ad980b47ea
Autor:
Ying-Chang Lu, Yi-Hsiu Tsai, Yen-Huei Chan, Chin-Ju Hu, Chun-Ying Huang, Ru Xiao, Chuan-Jen Hsu, Luk H. Vandenberghe, Chen-Chi Wu, Yen-Fu Cheng
Publikováno v:
JCI Insight, Vol 7, Iss 20 (2022)
Recessive PJVK mutations that cause a deficiency of pejvakin, a protein expressed in both sensory hair cells and first-order neurons of the inner ear, are an important cause of hereditary hearing impairment. Patients with PJVK mutations garner limite
Externí odkaz:
https://doaj.org/article/15f3b293c87e4224a8f987f5c20a90e0
Autor:
Chin-Ju Hu, Ying-Chang Lu, Yi-Hsiu Tsai, Haw-Yuan Cheng, Hiroki Takeda, Chun-Ying Huang, Ru Xiao, Chuan-Jen Hsu, Jin-Wu Tsai, Luk H. Vandenberghe, Chen-Chi Wu, Yen-Fu Cheng
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 493-500 (2020)
Sensorineural hearing loss is one of the most common sensory disorders worldwide. Recent advances in vector design have paved the way for investigations into the use of adeno-associated vectors (AAVs) for hearing disorder gene therapy. Numerous AAV s
Externí odkaz:
https://doaj.org/article/3d99ac29290f4535b5ffc081bedfe891
Autor:
Scott H. Greenwald, Emily E. Brown, Michael J. Scandura, Erin Hennessey, Raymond Farmer, Basil S. Pawlyk, Ru Xiao, Luk H. Vandenberghe, Eric A. Pierce
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 582-594 (2020)
No treatment is available for nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1)-associated retinal degeneration, an inherited disease that leads to severe vision loss early in life. Although the causative gene, NMNAT1, plays an essential rol
Externí odkaz:
https://doaj.org/article/5d02e3397cf744a298ba15f2fe1d0c82
Autor:
Pauline F. Schmit, Simon Pacouret, Eric Zinn, Elizabeth Telford, Fotini Nicolaou, Frédéric Broucque, Eva Andres-Mateos, Ru Xiao, Magalie Penaud-Budloo, Mohammed Bouzelha, Nicolas Jaulin, Oumeya Adjali, Eduard Ayuso, Luk H. Vandenberghe
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 107-121 (2020)
Generation and screening of libraries of adeno-associated virus (AAV) variants have emerged as a powerful method for identifying novel capsids for gene therapy applications. For the majority of libraries, vast population diversity requires multiplexe
Externí odkaz:
https://doaj.org/article/01e94c81cf474557ad14df40eac9da49
Autor:
Xionggao Huang, Guohong Zhou, Wenyi Wu, Yajian Duan, Gaoen Ma, Jingyuan Song, Ru Xiao, Luk Vandenberghe, Feng Zhang, Patricia A. D’Amore, Hetian Lei
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Abnormal angiogenesis causes many ocular diseases. Here the authors employ CRISPR/Cas9 gene editing technology to silence VEGFR2, a major regulator of angiogenesis, in retinal endothelium and abrogate angiogenesis in the mouse models of oxygen-induce
Externí odkaz:
https://doaj.org/article/f981fc904c1b403e9521fe12e9013ee3
Autor:
Eric Zinn, Simon Pacouret, Vadim Khaychuk, Heikki T. Turunen, Livia S. Carvalho, Eva Andres-Mateos, Samiksha Shah, Rajani Shelke, Anna C. Maurer, Eva Plovie, Ru Xiao, Luk H. Vandenberghe
Publikováno v:
Cell Reports, Vol 12, Iss 6, Pp 1056-1068 (2015)
Adeno-associated virus (AAV) vectors have emerged as a gene-delivery platform with demonstrated safety and efficacy in a handful of clinical trials for monogenic disorders. However, limitations of the current generation vectors often prevent broader
Externí odkaz:
https://doaj.org/article/9941e6a1cc964651b74a08eb30bc49f9
Autor:
Livia S. Carvalho, Heikki T. Turunen, Sarah J. Wassmer, María V. Luna-Velez, Ru Xiao, Jean Bennett, Luk H. Vandenberghe
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Retinal gene therapy has come a long way in the last few decades and the development and improvement of new gene delivery technologies has been exponential. The recent promising results from the first clinical trials for inherited retinal degeneratio
Externí odkaz:
https://doaj.org/article/7ab553c790b7459ca944b099def083d5