Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ru Han Jia"'
Publikováno v:
BMB Reports. 43:188-192
Inflammatory reactology has become increasingly important in diabetic kidney disease. In this study, we estabilished STZ-induced diabetic rat model to investigate whether dendritic cells (DCs) mediated tubulointerstitial damages, and whether the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cba2bfe98c88d5beed6911cf6cbce3c
https://doi.org/10.5483/bmbrep.2010.43.3.188
https://doi.org/10.5483/bmbrep.2010.43.3.188
Publikováno v:
Biochemical and Biophysical Research Communications. 380:81-86
Angiotensin II (Ang II) can stimulate Toll-like receptor 4 (TLR4) expression in mesangial cells (MCs), but the role of TLR4 in the Ang II-induced apoptosis and the effect of candesartan on TLR4 expression remain unclear. Here, we report that Ang II-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4446a6be92e12b1fc0f38ac7d2fd89a9
https://doi.org/10.1016/j.bbrc.2009.01.035
https://doi.org/10.1016/j.bbrc.2009.01.035
Publikováno v:
Mediators of Inflammation, Vol 2006 (2006)
Mediators of Inflammation
Mediators of Inflammation
Infiltration and local proliferation are known factors that contribute to tubulointerstitial macrophage accumulation. This study explored the time course of these two contributors' roles as tubulointerstitial inflammation and fibrosis progressing, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee341974f96a28e38752681139207f7
https://doi.org/10.1155/mi/2006/12919
https://doi.org/10.1155/mi/2006/12919
Publikováno v:
Zhonghua yi xue za zhi. 93(22)
Intracellular Ca(2+) overload is a key factor in contrast-induced renal tubular toxicity. Na(+)/Ca(2+) exchanger (NCX) system is one of main pathways of intracellular Ca(2+) overload. We explore the effects of KB-R7943, an inhibitor of reverse mode o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e553056f1f4ff078bff94366fee070e8
https://pubmed.ncbi.nlm.nih.gov/24124687
https://pubmed.ncbi.nlm.nih.gov/24124687
Publikováno v:
Zhonghua yi xue za zhi. 87(34)
To evaluate the effects of aldosterone (ald) on the expression of plasminogen activator inhibitor-1 (PAI-1) in renal mesangial cells (MCs) and the changes after aldosterone was blocked with spironolactone.Rat MCs of the line HBZY-1 were cultured and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::30a0e44f3fdb0a5395f0182232f87c3b
https://pubmed.ncbi.nlm.nih.gov/18036328
https://pubmed.ncbi.nlm.nih.gov/18036328
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System, Vol 8 (2007)
Introduction. To investigate the beneficial effects of spironolactone (SPL) on glomerular injury in streptozotocin (STZ)-induced diabetic rats and the possible mechanism.Methods and results. STZ-induced diabetic rats were divided into control group,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3329928da1a989c8e178dd5dccee8c99
https://pubmed.ncbi.nlm.nih.gov/17907099
https://pubmed.ncbi.nlm.nih.gov/17907099
Publikováno v:
Journal of biochemistry and molecular biology. 40(2)
In vivo studies have demonstrated that aldosterone is an independent contributor to glomerulosclerosis. In the present study, we have investigated whether aldosterone itself mediated glomerulosclerosis, as angiotensin II (Ang II) did, by inducing cul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be134ee8da69ca82e444d81957d34d1e
https://pubmed.ncbi.nlm.nih.gov/17394767
https://pubmed.ncbi.nlm.nih.gov/17394767
Publikováno v:
Pharmacology. 80(1)
Aim: To study whether rosiglitazone prevents the development of diabetic nephropathy through reduction of reactive oxygen species and its downstream signal transduction pathways.Methods: The rats were intraperitoneally injected with streptozotocin to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24542f121b8210fe1de42c3da6db0ca
https://pubmed.ncbi.nlm.nih.gov/17534120
https://pubmed.ncbi.nlm.nih.gov/17534120
Publikováno v:
Pharmacological research. 54(4)
Background Radiocontrast nephropathy (RCN) is a major complication after radiographic examination. The precise mechanisms underlying RCN are not well understood. Renal tubular cell apoptosis is a feature of RCN, but hyperosmolality cannot fully expla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2233c07266b3368e4ca106ad18783d68
https://pubmed.ncbi.nlm.nih.gov/16828304
https://pubmed.ncbi.nlm.nih.gov/16828304
Publikováno v:
American journal of nephrology. 25(5)
Background/Aims: Oxidative stress has been considered to be a common pathogenetic factor of diabetic nephropathy. But the reason why renal cells are susceptible to oxidative injury in diabetes is not clear. Vitamin C plays a central role in the antio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d156f013d3ee007f97b6fcf729cac328
https://pubmed.ncbi.nlm.nih.gov/16118484
https://pubmed.ncbi.nlm.nih.gov/16118484