Hintergrund und Design der TECOS-Studie (Trial Evaluating Cardiovasular Outcomes with Sitagliptin)

Autor: R Califf, RR Holman, A Bethel, M Hanefeld, A Riefflin

Publikováno v: Diabetologie und Stoffwechsel. 6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::788582d83462328442dabe3ba8c0e5ff
https://doi.org/10.1055/s-0031-1277435

Approach to maintaining comparability of biochemical data during long-term clinical trials

Autor: Ca, Cull, Se, Manley, irene stratton, Ha, Neil, Is, Ross, Rr, Holman, Rc, Turner, Dr, Matthews

Publikováno v: Europe PubMed Central

Our objective was to design a structured approach to maintaining comparability of biochemical data during a long clinical trial. Maintaining the comparability of clinical and biochemical data obtained in long-term studies is essential, even though an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7d277f18f852dcf6c476d44f0ab9505d
http://europepmc.org/abstract/med/9342012

Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes

Autor: Green JB, Bethel MA, Armstrong PW, Buse JB, Engel SS, Garg J, Josse R, Kaufman KD, Koglin J, Korn S, Lachin JM, McGuire DK, Pencina MJ, Standl E, Stein PP, Suryawanshi S, Van de Werf F, Peterson ED, Holman RR, Josse RG, Califf RM, Goldstein BJ, Shapiro DR, Silverman R, Bethel A, Green J, Hayden S, Hannan K, Quintero K, Rorick T, Berdan L, Leloudis D, Califf S, Wilson M, McFarron D, Trollinger K, Pesarchick J, Eskenazi L, Campbell C, Townes O, Tolsma D, Keenan J, Milton J, Athwal R, Darbyshire J, Doran Z, Kennedy I, Gregory V, Lokhnygina Y, Prather K, Wolfley A, Usman M, Tajjar A, Gray R, Pfeffer MA, Gerstein HC, Groop L, McMurray JJ, Pocock SJ, Clayton T, Sinay I, Brieger D, Stranks S, Scheen A, Lopes R, Tankova T, Hramiak I, Grado CR, Wenying Y, Ge J, Aschner P, Skrha J, Ambos A, Strandberg T, Travert F, Hanefeld M, Riefflin A, Chan JC, Ofner P, Reddy NK, Christopher J, Mathur A, Arambam P, Mittal S, Manchanda M, Wainstein J, Ambrosio G, Pirags V, Jakuboniene N, Mohamed M, Scott R, White H, Cornel J, Halvorsen S, Tykarski A, Veresiu IA, Dreval AV, Misinkova I, Tai E, Krahulec B, Distiller L, Park Y, Rovira A, Alversson M, Chuang LM, Delibasi T, Adler A, Rodbard HW, Marre M, Goff D, Chacra A, DeVore A, Beaven A, Shah B, Hirsch B, Batch B, Bushnell C, Patel C, Melloni C, Henshaw C, Kong D, Bernecki G, Tillman H, Kang HJ, Hawes J, Strickler J, Piccini J, Wilder J, Alexander K, Mahaffey K, Patel K, Hyland K, Newby K, Jackson L, Cooper L, Armaganijan L, Szczeh L, Koshizaka M, Roe M, Morse M, Guimaraes P, Hess P, Tricoci P, Mehta R, Mathews R, Kociol R, Harrison R, Mentz R, Pokorney S, Leblanc T, Lazzarini V, Eapen Z, Truffa A, Fosbol E, Brito F, Katz M, Bahit M, Santos M, Barros P, Bernardez S, Alvarisqueta AF, Arias P, Cagide AL, Calella PR, Cantero MC, Canella JP, Cipullo MA, de Loredo L, Gelersztein ES, Gorban de Lapertosa SB, Klyver MI, Maffei LE, Maldonado N, Oviedo AI, Piskorz DL, Ridruejo MC, Saavedra SS, Sessa HA, Sinay IR, Sposetti GD, Ulla MR, Vico ML, Waitman JN, Binnekamp M, Carroll P, Cheung W, Colman P, Davis T, De Looze F, dEmden M, Fulcher G, Gerstman M, Hamilton A, Lehman S, Moses R, Proietto J, Roberts A, Shaw J, Simpson R, Sinha A, Tan Y, Topliss D, Vora P, Waites J, Crenier L, Descamps O, Keymeulen B, Mathieu C, Nobels F, Van den Bruel A, Van Gaal L, Borges JL, Costa e Forti A, Eliaschewitz FG, Felício JS, Griz LH, Hissa MN, Leite S, Panarotto D, Pimentel Filho P, Rassi N, Saraiva JK, Sgarbi JA, Silva RP, Tambascia M, Weber Silva DM, Bobeva R, Bostandzhieva R, Cinlikov I, Georgieva M, Iliev D, Ilieva E, Kovacheva S, Liubenova L, Nikitov Z, SHeinikova G, Slavcheva A, Spasova V, Temelkova-Kurktschiev T, Velichka D, Yakov A, Carpentier A, Chiasson JL, Constance C, Dumas R, Filteau P, Garceau C, Huynh T, Kaiser S, Kornder J, Leiter L, Mereu L, Miller D, Pandey S, Punthakee Z, Rabasa-Lhoret R, Robitaille Y, Saunders K, Sigal R, Sigalas J, Vizel S, Weisnagel S, Woo V, Yale JF, Yared K, Zinman B, Bunster Balocchi LB, Escobar 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Shanik M, Snyder H, Sorli C, Stich M, Sweeney ME, Tsao J, Ukwade P, Viswanath D, Vo A, Vogel C, Voyce S, Weintraub H, White J, Wood M, Wu P, Wysham C, Zimmerman R

Publikováno v: New England Journal of Medicine. 373:232-242

BACKGROUND: Data are lacking on the long-term effect on cardiovascular events of adding sitagliptin, a dipeptidyl peptidase 4 inhibitor, to usual care in patients with type 2 diabetes and cardiovascular disease. METHODS: In this randomized, double-bl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0115f94b4333945408cd9a9c7dea2963
https://doi.org/10.1056/NEJMoa1501352

Younger-onset compared with later-onset type 2 diabetes: an analysis of the UK Prospective Diabetes Study (UKPDS) with up to 30 years of follow-up (UKPDS 92).

Autor: Lin B; Faculty of Medicine, University of Sydney, Sydney, NSW, Australia; Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Coleman RL; Faculty of Medicine, University of Sydney, Sydney, NSW, Australia., Bragg F; Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK; Health Data Research UK Oxford, University of Oxford, Oxford, UK., Maddaloni E; Experimental Medicine Department, Sapienza University of Rome, Rome, Italy., Holman RR; Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Adler AI; Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. Electronic address: amanda.adler@dtu.ox.ac.uk.

Publikováno v: The lancet. Diabetes & endocrinology [Lancet Diabetes Endocrinol] 2024 Dec; Vol. 12 (12), pp. 904-914. Date of Electronic Publication: 2024 Oct 23.

Using QALYs as an Outcome for Assessing Global Prediction Accuracy in Diabetes Simulation Models.

Autor: Dakin HA; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, UK., Gao N; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, UK.; Centre for Health Economics, University of York, York, UK., Leal J; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, UK., Holman RR; Diabetes Trials Unit, Radcliffe Department of Medicine, University of Oxford, UK., Tran-Duy A; Centre for Health Policy, Melbourne School of Population and Global Health, University of Melbourne, Australia., Clarke P; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, UK.

Publikováno v: Medical decision making : an international journal of the Society for Medical Decision Making [Med Decis Making] 2024 Oct 30, pp. 272989X241285866. Date of Electronic Publication: 2024 Oct 30.