Neutral rhodol-based dyes expressing localization in mitochondria.

Autor: Ferraboschi I; Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy. cristina.sissa@unipr.it., Ovčar J; Ruđer Bošković Institute, Bijenička cesta 54, 10000 Zagreb, Croatia. grisanti@iom.cnr.it.; National Research Council - Materials Foundry Institute (CNR-IOM) c/o SISSA (International School for Advanced Studies), Via Bonomea 265, 34136 Trieste, Italy., Vygranenko KV; Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland., Yu S; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, Newark, New Jersey 07102, USA., Minervino A; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, Newark, New Jersey 07102, USA., Wrzosek A; Nencki Institute of Experimental Biology of Polish Academy of Sciences, Pasteura 3, 02-093 Warsaw, Poland., Szewczyk A; Nencki Institute of Experimental Biology of Polish Academy of Sciences, Pasteura 3, 02-093 Warsaw, Poland., Rozza R; National Research Council - Materials Foundry Institute (CNR-IOM) c/o SISSA (International School for Advanced Studies), Via Bonomea 265, 34136 Trieste, Italy., Magistrato A; National Research Council - Materials Foundry Institute (CNR-IOM) c/o SISSA (International School for Advanced Studies), Via Bonomea 265, 34136 Trieste, Italy., Belfield KD; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, Newark, New Jersey 07102, USA., Gryko DT; Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland., Grisanti L; Ruđer Bošković Institute, Bijenička cesta 54, 10000 Zagreb, Croatia. grisanti@iom.cnr.it.; National Research Council - Materials Foundry Institute (CNR-IOM) c/o SISSA (International School for Advanced Studies), Via Bonomea 265, 34136 Trieste, Italy., Sissa C; Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy. cristina.sissa@unipr.it.

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2024 Jul 24; Vol. 22 (29), pp. 5886-5890. Date of Electronic Publication: 2024 Jul 24.

Assessing the Binding Mode of a Splicing Modulator Stimulating Pre-mRNA Binding to the Plastic U2AF2 Splicing Factor.

Autor: Rozza R; National Research Council of Italy (CNR)-Institute of Material Foundry (IOM) c/o International School for Advanced Studies (SISSA), Via Bonomea, 265, 34136 Trieste, Italy., Janoš P; National Research Council of Italy (CNR)-Institute of Material Foundry (IOM) c/o International School for Advanced Studies (SISSA), Via Bonomea, 265, 34136 Trieste, Italy., Magistrato A; National Research Council of Italy (CNR)-Institute of Material Foundry (IOM) c/o International School for Advanced Studies (SISSA), Via Bonomea, 265, 34136 Trieste, Italy.

Publikováno v: Journal of chemical information and modeling [J Chem Inf Model] 2023 Dec 11; Vol. 63 (23), pp. 7508-7517. Date of Electronic Publication: 2023 Nov 15.

Molecular Dynamics Simulations Elucidate the Molecular Basis of Pre-mRNA Translocation by the Prp2 Spliceosomal Helicase.

Autor: Agrò SN; National Research Council of Italy (CNR)─Institute of Material (IOM) c/o International School for Advanced Studies (SISSA), Via Bonomea, 265, 34136 Trieste, Italy., Rozza R; National Research Council of Italy (CNR)─Institute of Material (IOM) c/o International School for Advanced Studies (SISSA), Via Bonomea, 265, 34136 Trieste, Italy., Movilla S; BioComp Group, Institute of Advanced Materials (INAM), Universitat Jaume I, 12071 Castellón, Spain., Aupič J; National Research Council of Italy (CNR)─Institute of Material (IOM) c/o International School for Advanced Studies (SISSA), Via Bonomea, 265, 34136 Trieste, Italy., Magistrato A; National Research Council of Italy (CNR)─Institute of Material (IOM) c/o International School for Advanced Studies (SISSA), Via Bonomea, 265, 34136 Trieste, Italy.

Publikováno v: Journal of chemical information and modeling [J Chem Inf Model] 2023 Jul 10; Vol. 63 (13), pp. 4180-4189. Date of Electronic Publication: 2023 Jun 28.

Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment.

Autor: Gobbi S; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy., Martini S; Molecular Pharmacology Unit, Fondazione IRCSS Istituto Nazionale dei Tumori, Via Amadeo 42, 20113 Milano, Italy., Rozza R; National Research Council of Italy Institute of Materials (CNR-IOM) c/o SISSA, Via Bonomea 265, 34136 Trieste, Italy., Spinello A; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Viale delle Scienze, 90128 Palermo, Italy., Caciolla J; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy., Rampa A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy., Belluti F; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy., Zaffaroni N; Molecular Pharmacology Unit, Fondazione IRCSS Istituto Nazionale dei Tumori, Via Amadeo 42, 20113 Milano, Italy., Magistrato A; National Research Council of Italy Institute of Materials (CNR-IOM) c/o SISSA, Via Bonomea 265, 34136 Trieste, Italy., Bisi A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2023 Mar 29; Vol. 28 (7). Date of Electronic Publication: 2023 Mar 29.

Role of computational and structural biology in the development of small-molecule modulators of the spliceosome.

Autor: Rozza R; National Research Council of Italy, Institute of Materials-foundry (CNR-IOM) C/o SISSA, Trieste, Italy., Janoš P; National Research Council of Italy, Institute of Materials-foundry (CNR-IOM) C/o SISSA, Trieste, Italy., Spinello A; Department of Biological, Chemical and Pharmaceutical Sciences, University of Palermo, Palermo, Italy., Magistrato A; National Research Council of Italy, Institute of Materials-foundry (CNR-IOM) C/o SISSA, Trieste, Italy.

Publikováno v: Expert opinion on drug discovery [Expert Opin Drug Discov] 2022 Oct; Vol. 17 (10), pp. 1095-1109. Date of Electronic Publication: 2022 Aug 24.