DNA Methylation-Based Assessment of Cell Composition in Human Pancreas and Islets.

Autor: Drawshy Z; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), Hebrew University-Hadassah Medical School, Jerusalem, Israel., Neiman D; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), Hebrew University-Hadassah Medical School, Jerusalem, Israel., Fridlich O; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), Hebrew University-Hadassah Medical School, Jerusalem, Israel., Peretz A; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), Hebrew University-Hadassah Medical School, Jerusalem, Israel., Magenheim J; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), Hebrew University-Hadassah Medical School, Jerusalem, Israel., Rozo AV; Human Pancreas Analysis Program, University of Pennsylvania, Philadelphia, PA.; Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Doliba NM; Human Pancreas Analysis Program, University of Pennsylvania, Philadelphia, PA.; Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Stoffers DA; Human Pancreas Analysis Program, University of Pennsylvania, Philadelphia, PA.; Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Kaestner KH; Human Pancreas Analysis Program, University of Pennsylvania, Philadelphia, PA.; Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Schatz DA; Department of Pediatrics, University of Florida, Gainesville, FL., Wasserfall C; Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL., Campbell-Thompson M; Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL., Shapiro J; Surgery Department, Faculty of Medicine and Dentistry, Li Ka Shing Centre for Research, Edmonton, Alberta, Canada., Kaplan T; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), Hebrew University-Hadassah Medical School, Jerusalem, Israel.; School of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel., Shemer R; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), Hebrew University-Hadassah Medical School, Jerusalem, Israel., Glaser B; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), Hebrew University-Hadassah Medical School, Jerusalem, Israel., Klochendler A; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), Hebrew University-Hadassah Medical School, Jerusalem, Israel., Dor Y; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), Hebrew University-Hadassah Medical School, Jerusalem, Israel.

Publikováno v: Diabetes [Diabetes] 2024 Apr 01; Vol. 73 (4), pp. 554-564.

α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody-positive individuals.

Autor: Doliba NM; Department of Biochemistry and Biophysics.; Institute for Diabetes, Obesity, and Metabolism., Rozo AV; Institute for Diabetes, Obesity, and Metabolism.; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine., Roman J; Department of Biochemistry and Biophysics., Qin W; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine., Traum D; Department of Genetics, and., Gao L; Department of Genetics, and., Liu J; Department of Genetics, and., Manduchi E; Department of Genetics, and., Liu C; Institute for Diabetes, Obesity, and Metabolism.; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Golson ML; Institute for Diabetes, Obesity, and Metabolism.; Department of Genetics, and., Vahedi G; Institute for Diabetes, Obesity, and Metabolism.; Department of Genetics, and., Naji A; Institute for Diabetes, Obesity, and Metabolism.; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Matschinsky FM; Department of Biochemistry and Biophysics.; Institute for Diabetes, Obesity, and Metabolism., Atkinson MA; Departments of Pathology, Immunology, and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, Florida, USA.; Department of Pediatrics, University of Florida Diabetes Institute, College of Medicine, Gainesville, Florida, USA., Powers AC; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA.; VA Tennessee Valley Healthcare System, Nashville, Tennessee, USA., Brissova M; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA., Kaestner KH; Institute for Diabetes, Obesity, and Metabolism.; Department of Genetics, and., Stoffers DA; Institute for Diabetes, Obesity, and Metabolism.; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2022 Jun 01; Vol. 132 (11).

ATF5 regulates β-cell survival during stress.

Autor: Juliana CA; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104.; Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104., Yang J; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104.; Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104., Rozo AV; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104.; Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104., Good A; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104.; Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104., Groff DN; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104.; Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104., Wang SZ; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.; Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, MA 01605., Green MR; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605; Michael.Green@umassmed.edu stoffers@mail.med.upenn.edu.; Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, MA 01605., Stoffers DA; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104; Michael.Green@umassmed.edu stoffers@mail.med.upenn.edu.; Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Feb 07; Vol. 114 (6), pp. 1341-1346. Date of Electronic Publication: 2017 Jan 23.