Zobrazeno 1 - 10
of 470
pro vyhledávání: '"Rozman Jan"'
Autor:
Rozman, Jan, Yeomans, Julia M.
We study a mixture of extensile and contractile cells using a vertex model extended to include active nematic stresses. The two cell populations phase separate over time. While phase separation strengthens monotonically with an increasing magnitude o
Externí odkaz:
http://arxiv.org/abs/2407.19591
Tissue homeostasis, the biological process of maintaining a steady state in tissue via control of cell proliferation, death, and metabolic function, is essential for the development, growth, maintenance, and proper function of living organisms. Disru
Externí odkaz:
http://arxiv.org/abs/2403.15896
The mechanics of epithelial tissues, which is governed by forces generated in various cell domains, is often investigated using two-dimensional models that account for the apically-positioned actomyosin structures but neglect basolateral mechanics. W
Externí odkaz:
http://arxiv.org/abs/2402.19312
Complex tissue flows in epithelia are driven by intra- and inter-cellular processes that generate, maintain, and coordinate mechanical forces. There has been growing evidence that cell shape anisotropy, manifested as nematic order, plays an important
Externí odkaz:
http://arxiv.org/abs/2312.11756
We study the vertex model for epithelial tissue mechanics extended to include coupling between the cell shapes and tensions in cell-cell junctions. This coupling represents an active force which drives the system out of equilibrium and leads to the f
Externí odkaz:
http://arxiv.org/abs/2212.11037
Publikováno v:
Eur. Phys. J. E 44, 99 (2021)
Using a three-dimensional active vertex model, we numerically study the shapes of strained unsupported epithelial monolayers subject to active junctional noise due to stochastic binding and unbinding of myosin. We find that while uniaxial, biaxial, a
Externí odkaz:
http://arxiv.org/abs/2102.02224
Autor:
Hrabě de Angelis Martin, Gailus-Durner Valérie, Fuchs Helmut, Rödel Heiko G, Rozman Jan, Götz Alexander A, Klingenspor Martin, Stoeger Tobias
Publikováno v:
Particle and Fibre Toxicology, Vol 8, Iss 1, p 30 (2011)
Abstract Background Obesity can be linked to disease risks such as diabetes and cardiovascular disorders, but recently, the adipose tissue (AT) macrophage also emerges as actively participating in inflammation and immune function, producing pro- and
Externí odkaz:
https://doaj.org/article/766a68d922214091b13070b09c67d16f
Publikováno v:
Nat. Commun. 11, 3805 (2020)
The study of organoids, artificially grown cell aggregates with the functionality and small-scale anatomy of real organs, is one of the most active areas of research in biology and biophysics, yet the basic physical origins of their different morphol
Externí odkaz:
http://arxiv.org/abs/1910.11919
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Autor:
Hönes, Georg Sebastian, Geist, Daniela, Wenzek, Christina, Pfluger, Paul Thomas, Müller, Timo Dirk, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, Dragano, Natalia, Garrett, Lillian, Hölter, Sabine Maria, Rathkolb, Birgit, Rozman, Jan, Spielmann, Nadine, Treise, Irina, Wolf, Eckhard, Wurst, Wolfgang, Fuchs, Helmut, Gailus-Durner, Valerie, Angelis, Martin Hrabe de
Publikováno v:
Endocrinology; Aug2024, Vol. 165 Issue 8, p1-16, 16p