Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rozlyn A. Krajcik"'
Autor:
Carmen E. Perrone, Dwight A.L. Mattocks, George Hristopoulos, Jason D. Plummer, Rozlyn A. Krajcik, Norman Orentreich
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 1, Pp 12-23 (2008)
Methionine restriction (MR) limits age-related adiposity in Fischer 344 (F344) rats. To assess the mechanism of adiposity resistance, the effect of MR on adipose tissue (AT) 11β-hydroxysteroid dehydrogenase-1 (11β-HSD1) was examined. MR induced 11
Externí odkaz:
https://doaj.org/article/ac99f0b2582645d4bdc0fdfc239b8f73
Autor:
Laura K. Stewart, Anik Boudreau, Thomas W. Gettys, Virginia Malloy, Jeho Shin, Barbara E. Hasek, Rozlyn A. Krajcik, Tara M. Henagan, Norman Orentreich, Eric P. Plaisance, Natalie R. Lenard, Peter Huypens, Corey Black
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 299:R728-R739
Dietary methionine restriction (MR) is a mimetic of chronic dietary restriction (DR) in the sense that MR increases rodent longevity, but without food restriction. We report here that MR also persistently increases total energy expenditure (EE) and l
Autor:
Glenna C. Burmer, Nancy J. Linford, Vasiliki Demas, Peter S. Rabinovitch, Richard P. Beyer, Rozlyn A. Krajcik, Virginia L. Malloy, Katherine A. Gollahon
Publikováno v:
Aging Cell. 6:673-688
Sustained caloric restriction (CR) extends lifespan in animal models but the mechanism and primary tissue target(s) have not been identified. Gene expression changes with aging and CR were examined in both heart and white adipose tissue (WAT) of Fisc
Autor:
Rozlyn A. Krajcik, George Hristopoulos, Steven J. Bailey, Jason D. Plummer, Virginia Malloy, Norman Orentreich
Publikováno v:
Aging Cell. 5:305-314
Reduced dietary methionine intake (0.17% methionine, MR) and calorie restriction (CR) prolong lifespan in male Fischer 344 rats. Although the mechanisms are unclear, both regimens feature lower body weight and reductions in adiposity. Reduced fat dep
Publikováno v:
Journal of the American Academy of Dermatology. 48:752-759
Human hair follicles were grafted onto 2 strains of immunodeficient mice to compare the regeneration potential of vellus (miniaturized, balding) and terminal (hairy, nonbalding) follicles from males and a female exhibiting pattern baldness. Each mous
Publikováno v:
Clinical Chemistry. 48:2248-2251
Recent studies have correlated high serum insulin-like growth factor-1 (IGF-1) with increased risk of several common cancers, primarily prostate, breast, colorectum, and lung (1)(2)(3); low concentrations of circulating IGF-1 have been associated wit
Autor:
Anik Boudreau, Thomas W. Gettys, Rozlyn A. Krajcik, Kasey L. Hill, William D. Johnson, Carmen E. Perrone, Frank L. Greenway, William T. Cefalu, Norman Orentreich, Eric P. Plaisance
In preclinical reports, restriction of dietary methionine intake was shown to enhance metabolic flexibility, improve lipid profiles, and reduce fat deposition. The present report is the outcome of a "proof of concept" study to evaluate the efficacy o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17719d4d1d0e085ed679f716de9c7849
https://europepmc.org/articles/PMC3085194/
https://europepmc.org/articles/PMC3085194/
Autor:
Carmen E. Perrone, Norman Orentreich, George Hristopoulos, Jason D. Plummer, Rozlyn A. Krajcik, Dwight A.L. Mattocks
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 1, Pp 12-23 (2008)
Methionine restriction (MR) limits age-related adiposity in Fischer 344 (F344) rats. To assess the mechanism of adiposity resistance, the effect of MR on adipose tissue (AT) 11beta-hydroxysteroid dehydrogenase-1 (11beta-HSD1) was examined. MR induced
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 12(9)
Publikováno v:
Experimental gerontology. 38(1-2)
For more than 60 years the only dietary manipulation known to retard aging was caloric restriction, in which a variety of species respond to a reduction in energy intake by demonstrating extended median and maximum life span. More recently, two alter