Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rozita Adib"'
Autor:
Ivana Slamova, Rozita Adib, Stephan Ellmerich, Michal R. Golos, Janet A. Gilbertson, Nicola Botcher, Diana Canetti, Graham W. Taylor, Nigel Rendell, Glenys A. Tennent, Guglielmo Verona, Riccardo Porcari, P. Patrizia Mangione, Julian D. Gillmore, Mark B. Pepys, Vittorio Bellotti, Philip N. Hawkins, Raya Al-Shawi, J. Paul Simons
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
ATTR amyloidosis causes heart failure through the accumulation of misfolded transthyretin in cardiac muscle. Here the authors report a mouse model of ATTR amyloidosis and demonstrate the involvement of protease activity in ATTR amyloid deposition.
Externí odkaz:
https://doaj.org/article/52dd9743e5e94eff8fed79314e07bdac
Autor:
Lisa Crozier, Reece Foy, Rozita Adib, Mihaly Badonyi, Ananya Kar, Jordan A. Holt, Rona Wilson, Clement Regnault, Phil Whitfield, Joseph A. Marsh, Adrian Saurin, Alexis R. Barr, Tony Ly
SUMMARYCell size and the cell cycle are intrinsically coupled and abnormal increases in cell size are associated with senescence. The mechanism by which overgrowth primes cells to exit the cell cycle remains unclear. We investigate this using CDK4/6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e8f4908a9cdbc9ae91c040b33a0a8bb
https://doi.org/10.1101/2022.09.08.506843
https://doi.org/10.1101/2022.09.08.506843
Autor:
Chang Gok Woo, Hui Jeong Jeong, Richard Bayliss, Giancarlo Barone, Jene Choi, Spencer J. Collis, Patricia A.J. Muller, Dean A. Fennell, Emily L. Richardson, Rozita Adib, Laura O'Regan, Mark W. Richards, Andrew M. Fry
Publikováno v:
J Cell Sci
EML4–ALK is an oncogenic fusion present in ∼5% of non-small cell lung cancers. However, alternative breakpoints in the EML4 gene lead to distinct variants of EML4–ALK with different patient outcomes. Here, we show that, in cell models, EML4–A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81196d9a3e630f8380c716ed62c7d7a
https://pubmed.ncbi.nlm.nih.gov/32184261
https://pubmed.ncbi.nlm.nih.gov/32184261
Autor:
Jene Choi, Patricia A.J. Muller, Spencer J. Collis, Rozita Adib, Mark W. Richards, Hui Jeong Jeong, Emily L. Richardson, Richard Bayliss, Laura O'Regan, Chang Gok Woo, Dean A. Fennell, Giancarlo Barone, Andrew M. Fry
Publikováno v:
SSRN Electronic Journal.
EML4-ALK is an oncogenic fusion present in ∼5% lung adenocarcinomas. However, distinct EML4-ALK variants differ in the length of the EML4 microtubule-associated protein encoded within the fusion and are associated with a poorly understood variabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144814418dca75c937889eb50afc12ac
https://doi.org/10.2139/ssrn.3377373
https://doi.org/10.2139/ssrn.3377373
Autor:
Andrew M. Fry, Mark W. Richards, Carolyn A. Moores, Anne Straube, Laura O'Regan, K.R. Straatman, Richard Bayliss, Jessica M. Montgomery, Rozita Adib, Joseph Atherton, Daniel Roth
EML4 is a microtubule-associated protein that promotes microtubule stability. We show here that EML4 is distributed as punctate foci along the microtubule lattice in interphase but exhibits reduced association with spindle microtubules in mitosis. Mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bed64e26b25f8668a290d8a2d00fd9b
https://doi.org/10.1101/466979
https://doi.org/10.1101/466979
Publikováno v:
Biochemical Society transactions. 44(5)
The EMLs are a conserved family of microtubule-associated proteins (MAPs). The founding member was discovered in sea urchins as a 77-kDa polypeptide that co-purified with microtubules. This protein, termed EMAP for echinoderm MAP, was the major non-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf19e040a3bdede53762f1950df14415
https://pubmed.ncbi.nlm.nih.gov/27911710
https://pubmed.ncbi.nlm.nih.gov/27911710
Autor:
Peter W. Andrew, Irina Elliott, Nina Ivanovska, Luke Richards, S. Byrne, Wilhelm J. Schwaeble, Petya Dimitrova, Lee Machado, Cordula M. Stover, Hannah Brewin, Fatima Mohamed, Aline Dupont, Aras Kadioglu, Nur'Ain Salehen, Rozita Adib, Lorenza Francescut, Sarah Glenn
Publikováno v:
Medical Microbiology and Immunology
Streptococcus pneumoniae and Listeria monocytogenes, pathogens which can cause severe infectious disease in human, were used to infect properdin-deficient and wildtype mice. The aim was to deduce a role for properdin, positive regulator of the altern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f462e1bb651c8d814137792140eced96
http://nectar.northampton.ac.uk/11034/1/Dupont_Aline_etal_SL_2014_Septicaemia_models_using_Streptococcus_pneumoniae_and_Listeria_monocytogenes_understanding_the_role_of_complement_properdin.pdf
http://nectar.northampton.ac.uk/11034/1/Dupont_Aline_etal_SL_2014_Septicaemia_models_using_Streptococcus_pneumoniae_and_Listeria_monocytogenes_understanding_the_role_of_complement_properdin.pdf