Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Rozana Othman"'
Autor:
Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Adel S. Al-Zubairi, Ahmad Syahida, Lee KaHeng, Putri Narrima, Rozana Othman, Hassan Ahmad Alfaifi, Amal Hamdan Alzahrani
Publikováno v:
AIMS Molecular Science, Vol 11, Iss 3, Pp 262-276 (2024)
Faidherbia albida (Delile) A. Chev, a type of tree in the Leguminosae family, has several traditional uses. This study investigates the antioxidant properties, phenolic and flavonoid contents, nitric acid modulatory effects, and cytotoxicity of metha
Externí odkaz:
https://doaj.org/article/dd5d9995d8e34337947a77343d9316ce
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 2080 (2023)
Targeting folate receptors is a potential solution to low tumor selectivity concerning conventional chemotherapeutics. Apart from antibody–drug conjugates, folate-functionalized nanoparticle drug delivery systems are interesting to be explored due
Externí odkaz:
https://doaj.org/article/cca4f28c13c54607b4a9c3b57f2669ae
Autor:
Sri Devi Sukumaran, Shah Bakhtiar Nasir, Jia Ti Tee, Michael J. C. Buckle, Rozana Othman, Noorsaadah Abd. Rahman, Vannajan Sanghiran Lee, Syed Nasir Abbas Bukhari, Chin Fei Chee
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 130-137 (2021)
A series of C4-substituted tertiary nitrogen-bearing 2′-hydroxychalcones were designed and synthesised based on a previous mixed type acetylcholinesterase inhibitor. Majority of the 2′-hydroxychalcone analogues displayed a better inhibition again
Externí odkaz:
https://doaj.org/article/37cdbd5235784789a3d4a30b4130a07a
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 12, Iss 6, Pp 676-680 (2020)
The naturally derived flavonoids are well known to have anticarcinogenic effects. Flavonoids could be an alternative strategy for ovarian cancer treatment, due to existing platinum-based drugs are reported to develop resistance with low survival rate
Externí odkaz:
https://doaj.org/article/0840bff13a35468fa026b08055167ccd
Autor:
Cheok Wui Chee, Nor Hisam Zamakshshari, Vannajan Sanghiran Lee, Iskandar Abdullah, Rozana Othman, Yean Kee Lee, Najihah Mohd Hashim, Nurshamimi Nor Rashid
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270970 (2022)
There is an increasing demand in developing new, effective, and affordable anti-cancer against colon and rectal. In this study, our aim is to identify the potential anthraquinone compounds from the root bark of Morinda citrifolia to be tested in vitr
Externí odkaz:
https://doaj.org/article/b540536d2ca84cbc821f7c85819c36fd
Autor:
Norburhanuddin Johari Zaidi, Adib Afandi Abdullah, Choon Han Heh, Chun-Hung Lin, Rozana Othman, Abdullah Al Hadi Ahmad Fuaad
Publikováno v:
Molecules, Vol 27, Iss 10, p 3233 (2022)
Data from the World Health Organisation show that the global incidence of dengue infection has risen drastically, with an estimated 400 million cases of dengue infection occurring annually. Despite this worrying trend, there is still no therapeutic t
Externí odkaz:
https://doaj.org/article/45319695ced44eb29840b1f42f3f124a
Autor:
Mohammad G. Al-Thiabat, Amirah Mohd Gazzali, Noratiqah Mohtar, Vikneswaran Murugaiyah, Ezatul Ezleen Kamarulzaman, Beow Keat Yap, Noorsaadah Abd Rahman, Rozana Othman, Habibah A. Wahab
Publikováno v:
Molecules, Vol 26, Iss 17, p 5304 (2021)
Drug targeting is a progressive area of research with folate receptor alpha (FRα) receiving significant attention as a biological marker in cancer drug delivery. The binding affinity of folic acid (FA) to the FRα active site provides a basis for re
Externí odkaz:
https://doaj.org/article/02e6aac2213a40c6a540cf25239694ba
Autor:
Maywan Hariono, Sy Bing Choi, Ros Fatihah Roslim, Mohamed Sufian Nawi, Mei Lan Tan, Ezatul Ezleen Kamarulzaman, Nornisah Mohamed, Rohana Yusof, Shatrah Othman, Noorsaadah Abd Rahman, Rozana Othman, Habibah A Wahab
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210869 (2019)
Dengue virus Type 2 (DENV-2) is predominant serotype causing major dengue epidemics. There are a number of studies carried out to find its effective antiviral, however to date, there is still no molecule either from peptide or small molecules release
Externí odkaz:
https://doaj.org/article/09805d18963c4b51980b147b1e2df79b
Autor:
Nor Hisam Zamakshshari, Idris Adewale Ahmed, Muhammad Nazil Afiq Nasharuddin, Nurul Syahira Zaharudin, Najihah Mohd Hashim, Rozana Othman
Publikováno v:
Chemistry & Biodiversity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24ac4dec819a5441e44a66038f667857
https://doi.org/10.1002/cbdv.202300111
https://doi.org/10.1002/cbdv.202300111
Autor:
Chin Fei Chee, Nurhaliza Wati Mekzali, Cheok Wui Chee, Iskandar Abdullah, Yean Kee Lee, Nurshamimi Nor Rashid, Vannajan Sanghiran Lee, Rozana Othman, Najihah Mohd Hashim
Publikováno v:
Medicinal Chemistry. 19
Background: KRAS and p53 are two of the most common genetic alterations associated with colorectal cancer. New drug development targeting these mutated genes in colorectal cancer may serve as a potential treatment avenue to the current regimen. Objec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eb3d0f1d7987766485cb59bae1d3ece
https://doi.org/10.2174/1573406419666230410134213
https://doi.org/10.2174/1573406419666230410134213