Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rozalia Dodean"'
Autor:
Anasuya C Pal, Isaline Renard, Pallavi Singh, Pratap Vydyam, Joy E Chiu, Sovitj Pou, Rolf W Winter, Rozalia Dodean, Lisa Frueh, Aaron C Nilsen, Michael K Riscoe, J Stone Doggett, Choukri Ben Mamoun
Publikováno v:
J Infect Dis
Human babesiosis is a malaria-like illness caused by tick-borne intraerythrocytic Babesia parasites of the Apicomplexa phylum. Whereas several species of Babesia can cause severe disease in humans, the ability to propagate Babesia duncani both in vit
Autor:
Katherine M. Liebman, Aaron Nilsen, Rolf W. Winter, Michael K. Riscoe, Lisa Frueh, David R. Stuart, Robert T. Jacobs, J. Stone Doggett, Rory T. Gallagher, Haihong Jin, Sovitj Pou, Rozalia Dodean
Publikováno v:
Organic Process Research & Development. 25:1841-1852
Autor:
Pallavi Singh, Michael K. Riscoe, Aaron Nilsen, Choukri Ben Mamoun, Anasuya Chattopadhyay Pal, Isaline Renard, Shalev Gihaz, Pratap Vydyam, Rolf W. Winter, Madelyn Kumar, Sovitj Pou, Rozalia Dodean, Joy E. Chiu, Jose Thekkiniath, J. Stone Doggett, Lisa Frueh
Publikováno v:
Antimicrobial Agents and Chemotherapy. 65
An effective strategy to control blood-borne diseases and prevent outbreak recrudescence involves targeting conserved metabolic processes that are essential for pathogen viability. One such target for Plasmodium and Babesia, the infectious agents of
Autor:
Joy E, Chiu, Isaline, Renard, Anasuya C, Pal, Pallavi, Singh, Pratap, Vydyam, Jose, Thekkiniath, Madelyn, Kumar, Shalev, Gihaz, Sovitj, Pou, Rolf W, Winter, Rozalia, Dodean, Lisa, Frueh, Aaron C, Nilsen, Michael K, Riscoe, J Stone, Doggett, Choukri Ben, Mamoun
Publikováno v:
Antimicrob Agents Chemother
An effective strategy to control blood-borne diseases and prevent outbreak recrudescence involves targeting conserved metabolic processes that are essential for pathogen viability. One such target for Plasmodium and Babesia, the infectious agents of
Autor:
Joy E. Chiu, J. Stone Doggett, Pratap Vydyam, Rozalia Dodean, Pallavi Singh, Sovitj Pou, Anasuya Chattopadhyay Pal, Jose Thekkiniath, Rolf W. Winter, Shalev Gihaz, Isaline Renard, Aaron Nilsen, Choukri Ben Mamoun, Madelyn Kumar, Michael K. Riscoe
Targeting conserved metabolic processes that are essential for viability of pathogens, such as Plasmodium and Babesia that cause blood-borne diseases, is an effective strategy to eliminate malaria and babesiosis infections with no recrudescence. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3310f6691c52ed40b816b958b25fd4e3
https://doi.org/10.1101/2021.03.31.438003
https://doi.org/10.1101/2021.03.31.438003
Autor:
Carlos E. Suarez, J. Stone Doggett, Aaron Nilsen, Michael K. Riscoe, Rozalia Dodean, Sovitj Pou, Rolf W. Winter, Reginaldo G. Bastos, Marta G. Silva
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-11 (2020)
Parasites & Vectors
Parasites & Vectors
Background The most common apicomplexan parasites causing bovine babesiosis are Babesia bovis and B. bigemina, while B. caballi and Theileria equi are responsible for equine piroplasmosis. Treatment and control of these diseases are usually achieved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04a3ba5994621185e089d10d042af49
https://doi.org/10.21203/rs.3.rs-58018/v2
https://doi.org/10.21203/rs.3.rs-58018/v2
Autor:
Rolf W. Winter, Tracey L. Schultz, Vern B. Carruthers, Aaron Nilsen, Sovitj Pou, Alyssa J. Miller, Michael K. Riscoe, Rozalia Dodean, Lev N. Zakharov, Igor Bruzual, J. Stone Doggett
Publikováno v:
Antimicrob Agents Chemother
Toxoplasmosis is a potentially fatal infection for immunocompromised people and the developing fetus. Current medicines for toxoplasmosis have high rates of adverse effects that interfere with therapeutic and prophylactic regimens. Endochin-like quin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e4e76a1889fea9d2161ea769f0fe7b
https://europepmc.org/articles/PMC7449172/
https://europepmc.org/articles/PMC7449172/
Autor:
J. Stone Doggett, Sovitj Pou, Michael K. Riscoe, Igor Bruzual, Alina Krollenbrock, Aaron Nilsen, Rolf W. Winter, Erin V. McConnell, Martin J. Smilkstein, Rozalia Dodean, Lev N. Zakharov
Publikováno v:
ACS Infectious Diseases. 4:1574-1584
Cytochrome bc1 inhibitors have been broadly studied as human and veterinary medicines and agricultural fungicides. For the most part, cytochrome bc1 inhibitors compete with ubiquinol at the ubiquinol oxidation (Qo) site or with ubiquinone at the quin
Autor:
Aaron Nilsen, Thomas Martinson, Alina Krollenbrock, Lisa Frueh, Lisa Bleyle, Rozalia Dodean, Samantha Whiteside, Igor Bruzual, David J. Hinrichs, Dennis R. Koop, Stefan H. I. Kappe, Sovitj Pou, Michael K. Riscoe, Jane Xu Kelly, Martin J. Smilkstein, Myrna Y. Munar, Rolf W. Winter, Yuexin Li, Brandon K. Wilder
Publikováno v:
Malaria Journal
Malaria Journal, Vol 18, Iss 1, Pp 1-17 (2019)
Malaria Journal, Vol 18, Iss 1, Pp 1-17 (2019)
BackgroundThe potential benefits of long-acting injectable chemoprotection (LAI-C) against malaria have been recently recognized, prompting a call for suitable candidate drugs to help meet this need. On the basis of its known pharmacodynamic and phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e9df3dea5dabbdc535615107019ec2
Autor:
Martin J. Smilkstein, Rolf W. Winter, Roland A. Cooper, Aaron Janowsky, Jane X. Kelly, Michael K. Riscoe, David J. Hinrichs, Sergio Wittlin, Reto Brun, Robert A. Johnson, Kristin D. Lane, Rozalia Dodean
Publikováno v:
Nature
Preventing and delaying the emergence of drug resistance is an essential goal of antimalarial drug development. Monotherapy and highly mutable drug targets have each facilitated resistance, and both are undesirable in effective long-term strategies a