Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Roza Zandi"'
Autor:
Jing Lin, Roza Zandi, Ruping Shao, Jian Gu, Yuanqin Ye, Jing Wang, Yang Zhao, Alexander Pertsemlidis, Ignacio I. Wistuba, Xifeng Wu, Jack A. Roth, Lin Ji
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Through a new hypothesis-driven and microRNA-pathway-based SNP (miR-SNP) association study we identified a novel miR-SNP (rs713065) in the 3′UTR region of FZD4 gene linked with decreased risk of death in early stage NSCLC patients. We dete
Externí odkaz:
https://doaj.org/article/b2795e546e554183a50a6e56dd7ff1b4
Autor:
Hans Skovgaard Poulsen, Berthe Marie Willumsen, Thomas Alexander Gerds, Camilla Laulund Christensen, Galina Selivanova, Roza Zandi
Purpose: Small cell lung cancer (SCLC) is a highly malignant disease with poor prognosis, necessitating the need to develop new and efficient treatment modalities. PRIMA-1Met (p53-dependent reactivation of massive apoptosis), also known as APR-246, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e369ef77f8c2e3b6fb36bc6cb8779a6
https://doi.org/10.1158/1078-0432.c.6519203
https://doi.org/10.1158/1078-0432.c.6519203
Autor:
Hans Skovgaard Poulsen, Berthe Marie Willumsen, Thomas Alexander Gerds, Camilla Laulund Christensen, Galina Selivanova, Roza Zandi
Supplementary Figures S1-S3; Supplementary Tables S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f5814d94a9a6bd019a567cebdee8fd
https://doi.org/10.1158/1078-0432.22442486
https://doi.org/10.1158/1078-0432.22442486
Autor:
Simon Husby, Mats Ehinger, Christian Garde, Jack B. Cowland, Jan Delabie, Christian H. Geisler, Arne Kolstad, Ulrik Ralfkiaer, Sara Ek, Lone Bredo Pedersen, Riikka Räty, Roza Zandi, Christopher T. Workman, Erik Clasen-Linde, Christer Sundström, Kirsten Grønbæk, Marja-Liisa Karjalainen-Lindsberg, Peter de Nully Brown, Anna Laurell, Mats Jerkeman, Anja Pedersen
Publikováno v:
Husby, S, Ralfkiær, U M, Garde, C, Zandi, R, Ek, S, Kolstad, A, Jerkeman, M, Laurell, A, Räty, R, Pedersen, L B, Pedersen, A, Ehinger, M, Sundström, C, Karjalainen-Lindsberg, M-L, Delabie, J, Clasen-Linde, E, Brown, P, Cowland, J B, Workman, C, Geisler, C H & Grønbæk, K 2015, ' miR-18b overexpression identifies mantle cell lymphoma patients with poor outcome and improves the MIPI-B prognosticator ', Blood, vol. 125, no. 17, pp. 2669-2677 . https://doi.org/10.1182/blood-2014-06-584193
Recent studies show that mantle cell lymphoma (MCL) express aberrant microRNA (miRNA) profiles; however, the clinical effect of miRNA expression has not previously been examined and validated in large prospective homogenously treated cohorts. We perf
Publikováno v:
Gene. 615
t(8;21) acute myeloid leukemia (AML) is characterized by a translocation between chromosomes 8 and 21 and formation of a distinctive RUNX1-RUNX1T1 fusion transcript. This translocation places RUNX1T1 under control of the RUNX1 promoter leading to a p
Publikováno v:
Scientific Reports
MicroRNAs (miRNAs) play an important role in targeted gene silencing by facilitating posttranscriptional and translational repression. However, the precise mechanism of mammalian miRNA-mediated gene silencing remains to be elucidated. Here, we used a
Publikováno v:
Cancer Investigation. 29:683-691
The candidate tumor suppressor fragile histidine traid (FHIT) is frequently inactivated in small cell lung cancer (SCLC). Mutations in the p53 gene also occur in the majority of SCLC leading to the accumulation of the mutant protein. Here we evaluate
Autor:
Mikkel W. Pedersen, Berthe M. Willumsen, Hans Skovgaard Poulsen, Bo van Deurs, Michael Vibo Grandal, Roza Zandi
Publikováno v:
Carcinogenesis. 28:1408-1417
EGFRvIII is a mutant variant of the epidermal growth factor receptor (EGFR) found exclusively in various cancer types. EGFRvIII lacks a large part of the extracellular domain and is unable to bind ligands; however, the receptor is constitutively phos
Autor:
Camilla L. Christensen, Roza Zandi, Berthe M. Willumsen, Hans Skovgaard Poulsen, Thomas A. Gerds, Galina Selivanova
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 17(9)
Purpose: Small cell lung cancer (SCLC) is a highly malignant disease with poor prognosis, necessitating the need to develop new and efficient treatment modalities. PRIMA-1Met (p53-dependent reactivation of massive apoptosis), also known as APR-246, i
Publikováno v:
Journal of Clinical & Experimental Pathology.
FUS1, also known as tumor suppressor candidate 2 (TUSC2), is a novel candidate tumor suppressor gene (TSG) frequently inactivated in human lung cancer. Loss of FUS1 protein expression is found in almost all small cell lung cancer (SCLC) cell lines an