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of 3
pro vyhledávání: '"Roza H. Ali Masalmeh"'
Autor:
Roza H. Ali Masalmeh, Francesca Taglini, Cristina Rubio-Ramon, Kamila I. Musialik, Jonathan Higham, Hazel Davidson-Smith, Ioannis Kafetzopoulos, Kamila P. Pawlicka, Hannah M. Finan, Richard Clark, Jimi Wills, Andrew J. Finch, Lee Murphy, Duncan Sproul
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Aberrant gain of DNA methylation at CpG islands is frequently observed in colorectal tumours. Here the authors use ectopically integrated CpG islands in colorectal cancer cells and find that aberrantly methylated CpG islands are subject to low levels
Externí odkaz:
https://doaj.org/article/9803ec9958634a5e94312be4787e0b29
Autor:
Richard Clark, Andrew J. Finch, Kamila Pawlicka, Kamila I. Musialik, Francesca Taglini, Hannah M. Finan, Duncan Sproul, Cristina Rubio-Ramon, Jonathan Higham, Ioannis Kafetzopoulos, Jimi Wills, Roza H. Ali Masalmeh, Lee Murphy, Hazel Davidson-Smith
Publikováno v:
Masalmeh, R, Taglini, F, Rubio Ramon, C, I. Musialik, K, Higham, J, Davidson-Smith, H, Kafetzopoulos, I, Pawlicka, K, M. Finan, H, Clark, R, Wills, J, J Finch, A, Murphy, L & Sproul, D 2021, ' De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands ', Nature . https://doi.org/10.1038/s41467-020-20716-w
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
The aberrant gain of DNA methylation at CpG islands is frequently observed in colorectal tumours and may silence the expression of tumour suppressors such as MLH1. Current models propose that these CpG islands are targeted by de novo DNA methyltransf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68586b09e62a83be64d10d0335c2e293
https://www.pure.ed.ac.uk/ws/files/193624007/s41467_020_20716_w.pdf
https://www.pure.ed.ac.uk/ws/files/193624007/s41467_020_20716_w.pdf
Autor:
Cristina Rubio-Ramon, Andrew J. Finch, Francesca Taglini, Jonathan Higham, Jimi Wills, Roza H. Ali Masalmeh, Richard Clark, Lee Murphy, Duncan Sproul, Hazel Davidson-Smith
The aberrant gain of DNA methylation at CpG islands (CGIs) is frequently observed in colorectal tumours and may silence the expression of tumour suppressors such asMLH1. Current models propose that these CGIs are targeted byde novoDNA methyltransfera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a8b9450629382735af4a56f21aa7d8