Zobrazeno 1 - 10
of 571
pro vyhledávání: '"Royston, Goodacre"'
Autor:
Safaa Al Jedani, Cassio Lima, Caroline I. Smith, Philip J. Gunning, Richard J. Shaw, Steve D. Barrett, Asterios Triantafyllou, Janet M. Risk, Royston Goodacre, Peter Weightman
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In this study, optical photothermal infrared (O-PTIR) spectroscopy combined with machine learning algorithms were used to evaluate 46 tissue cores of surgically resected cervical lymph nodes, some of which harboured oral squamous cell carcin
Externí odkaz:
https://doaj.org/article/ad74e1f542784fe9854419e35860e4ab
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The universe is a vast store of organic abiotic carbon that could potentially drive heterotrophy on habitable planets. Meteorites are one of the transporters of this carbon to planetary surfaces. Meteoritic material was accumulating on early
Externí odkaz:
https://doaj.org/article/0adb814f638849af880ec62e4377a469
Autor:
Shwan Ahmed, Jawaher Albahri, Sahand Shams, Silvana Sosa-Portugal, Cassio Lima, Yun Xu, Rachel McGalliard, Trevor Jones, Christopher M. Parry, Dorina Timofte, Enitan D. Carrol, Howbeer Muhamadali, Royston Goodacre
Publikováno v:
Microorganisms, Vol 12, Iss 7, p 1415 (2024)
Sepsis is a life-threatening condition arising from a dysregulated host immune response to infection, leading to a substantial global health burden. The accurate identification of bacterial pathogens in sepsis is essential for guiding effective antim
Externí odkaz:
https://doaj.org/article/29d2caab22604682b8da73a1f2df1bb9
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The rise and extensive spread of antimicrobial resistance (AMR) has become a growing concern, and a threat to the environment and human health globally. The majority of current AMR identification methods used in clinical setting are based on traditio
Externí odkaz:
https://doaj.org/article/2e3cbac6c1c64436bee875e35297630f
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0279669 (2023)
Discrimination of brain cancer versus non-cancer patients using serum-based attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy diagnostics was first developed by Hands et al with a reported sensitivity of 92.8% and specifi
Externí odkaz:
https://doaj.org/article/53fffc7a043340bcac3fb7bb207941c9
Autor:
Waqar Ahmed, Iain R. White, Maxim Wilkinson, Craig F. Johnson, Nicholas Rattray, Amit K. Kishore, Royston Goodacre, Craig J. Smith, Stephen J. Fowler
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Inflammation is strongly implicated in both injury and repair processes occurring after stroke. In this exploratory study we assessed the feasibility of repeated sampling of exhaled volatile organic compounds and performed an untargeted meta
Externí odkaz:
https://doaj.org/article/263bc1bb366f407493f151fb380588c1
Autor:
Antonio Valle, Maria Elena de la Calle, Howbeer Muhamadali, Katherine A. Hollywood, Yun Xu, Jonathan R. Lloyd, Royston Goodacre, Domingo Cantero, Jorge Bolivar
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11619 (2023)
The biological production of hydrogen is an appealing approach to mitigating the environmental problems caused by the diminishing supply of fossil fuels and the need for greener energy. Escherichia coli is one of the best-characterized microorganisms
Externí odkaz:
https://doaj.org/article/85b8a2abf4d24a97b5142765c481c3ee
Autor:
Thanyaporn Tengsuttiwat, Naheed Nazly Kaderbhai, Joe Gallagher, Royston Goodacre, Howbeer Muhamadali
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Optimization of recombinant protein expression in bacteria is an important task in order to increase protein yield while maintaining the structural fidelity of the product. In this study, we employ Fourier transform infrared (FT-IR) spectroscopy as a
Externí odkaz:
https://doaj.org/article/9db74e5df36845e6af589fa273c03dd8
Autor:
Eleanor Sinclair, Drupad K. Trivedi, Depanjan Sarkar, Caitlin Walton-Doyle, Joy Milne, Tilo Kunath, Anouk M. Rijs, Rob M. A. de Bie, Royston Goodacre, Monty Silverdale, Perdita Barran
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Studies of metabolites in neurodegeneration have not yet used sebum as a source fluid. Here the authors demonstrate the potential of metabolomics of sebum samples from individuals with Parkinson’s disease and controls.
Externí odkaz:
https://doaj.org/article/9e01bc89a95e413fbdff0e9ee7e5a51b
Autor:
Nicholas J. W. Rattray, Drupad K. Trivedi, Yun Xu, Tarani Chandola, Caroline H. Johnson, Alan D. Marshall, Krisztina Mekli, Zahra Rattray, Gindo Tampubolon, Bram Vanhoutte, Iain R. White, Frederick C. W. Wu, Neil Pendleton, James Nazroo, Royston Goodacre
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Risk of age-related chronic disorders and decrease in resilience is associated with ageing. Here the authors analyse the human blood metabolome and identify metabolites associated with frailty.
Externí odkaz:
https://doaj.org/article/f8a8be46f83b45fc975dd3c54a72ffd7