Airway Remodeling and Hyperreactivity in a Model of Bronchopulmonary Dysplasia and Their Modulation by IL-1 Receptor Antagonist

Autor: Royce, SG, Nold, MF, Bui, C, Donovan, C, Lam, M, Lamanna, E, Rudloff, I, Bourke, JE, Nold-Petry, CA

Bronchopulmonary dysplasia (BPD) is a chronic disease of extreme prematurity that has serious long-term consequences including increased asthma risk. We earlier identified IL-1 receptor antagonist (IL-1Ra) as a potent inhibitor of murine BPD induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::6bc2f3b35c9343ffc068773234bb5773
https://hdl.handle.net/10453/159945

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Aerosol Delivery of Palivizumab in a Neonatal Lamb Model of Respiratory Syncytial Virus Infection.

Autor: Edirisinghe HS; Murdoch Children's Research Institute, Melbourne 3052, Australia.; Department of Paediatrics, University of Melbourne, Melbourne 3010, Australia., Rajapaksa AE; Murdoch Children's Research Institute, Melbourne 3052, Australia.; Department of Paediatrics, University of Melbourne, Melbourne 3010, Australia.; Royal Children's Hospital, Melbourne 3052, Australia.; Royal Women's Hospital, Melbourne 3052, Australia., Royce SG; Monash Biomedicine Discovery Institute, Monash University, Melbourne 3168, Australia., Sourial M; Murdoch Children's Research Institute, Melbourne 3052, Australia.; Royal Children's Hospital, Melbourne 3052, Australia., Bischof RJ; Institute of Innovation, Science and Sustainability, Federation University, Melbourne 3806, Australia., Anderson J; Murdoch Children's Research Institute, Melbourne 3052, Australia.; Department of Paediatrics, University of Melbourne, Melbourne 3010, Australia., Sarila G; Murdoch Children's Research Institute, Melbourne 3052, Australia.; Department of Paediatrics, University of Melbourne, Melbourne 3010, Australia., Nguyen CD; Murdoch Children's Research Institute, Melbourne 3052, Australia., Mulholland K; Murdoch Children's Research Institute, Melbourne 3052, Australia.; Department of Paediatrics, University of Melbourne, Melbourne 3010, Australia., Do LAH; Murdoch Children's Research Institute, Melbourne 3052, Australia.; Department of Paediatrics, University of Melbourne, Melbourne 3010, Australia., Licciardi PV; Murdoch Children's Research Institute, Melbourne 3052, Australia.; Department of Paediatrics, University of Melbourne, Melbourne 3010, Australia.

Publikováno v: Viruses [Viruses] 2023 Nov 19; Vol. 15 (11). Date of Electronic Publication: 2023 Nov 19.

Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant, and epigenetic mechanisms.

Autor: Royce SG; Epigenomic Medicine Laboratory, Department of Diabetes, Central Clinical School, Monash University, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia.; Department of Clinical Pathology, University of Melbourne, Parkville, VIC, 3010, Australia.; Department of Pharmacology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia.; Infection and Immunity, Murdoch Children's Research Institute, Melbourne, VIC, 3052, Australia., Licciardi PV; Infection and Immunity, Murdoch Children's Research Institute, Melbourne, VIC, 3052, Australia.; Department of Paediatrics, The University of Melbourne, Melbourne, VIC, 3010, Australia., Beh RC; Epigenomic Medicine Laboratory, Department of Diabetes, Central Clinical School, Monash University, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia.; Department of Clinical Pathology, University of Melbourne, Parkville, VIC, 3010, Australia., Bourke JE; Department of Pharmacology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia., Donovan C; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, University of Newcastle, Newcastle, NSW, 2305, Australia.; Centre for Inflammation, Centenary Institute, Camperdown, NSW, 2050, Australia.; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, 2007, Australia., Hung A; School of Science, STEM College, RMIT University, VIC, 3001, Australia., Khurana I; Epigenetics in Human Health and Disease Laboratory, Department of Diabetes, Central Clinical School, Monash University, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia., Liang JJ; Epigenomic Medicine Laboratory, Department of Diabetes, Central Clinical School, Monash University, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia.; School of Science, STEM College, RMIT University, VIC, 3001, Australia., Maxwell S; Epigenetics in Human Health and Disease Laboratory, Department of Diabetes, Central Clinical School, Monash University, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia., Mazarakis N; Epigenomic Medicine Laboratory, Department of Diabetes, Central Clinical School, Monash University, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia.; Infection and Immunity, Murdoch Children's Research Institute, Melbourne, VIC, 3052, Australia.; Department of Paediatrics, The University of Melbourne, Melbourne, VIC, 3010, Australia.; Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, VIC, 3010, Australia., Pitsillou E; Epigenomic Medicine Laboratory, Department of Diabetes, Central Clinical School, Monash University, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia.; School of Science, STEM College, RMIT University, VIC, 3001, Australia., Siow YY; Epigenomic Medicine Laboratory, Department of Diabetes, Central Clinical School, Monash University, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia., Snibson KJ; Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, VIC, 3010, Australia., Tobin MJ; ANSTO-Australian Synchrotron, Clayton, VIC, 3168, Australia., Ververis K; Epigenomic Medicine Laboratory, Department of Diabetes, Central Clinical School, Monash University, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia.; Department of Clinical Pathology, University of Melbourne, Parkville, VIC, 3010, Australia., Vongsvivut J; ANSTO-Australian Synchrotron, Clayton, VIC, 3168, Australia., Ziemann M; Epigenetics in Human Health and Disease Laboratory, Department of Diabetes, Central Clinical School, Monash University, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia.; School of Life and Environmental Sciences, Deakin University, Waurn Ponds, Warrnambool, VIC, 3216, Australia., Samuel CS; Cardiovascular Disease Program, Monash Biomedicine Discovery Institute and Department of Pharmacology, Monash University, Clayton, VIC, 3800, Australia., Tang MLK; Department of Paediatrics, The University of Melbourne, Melbourne, VIC, 3010, Australia.; Population Allergy Group, Murdoch Children's Research Institute, Parkville, VIC, 3052, Australia.; Department of Allergy and Immunology, Royal Children's Hospital, Parkville, VIC, 3052, Australia., El-Osta A; Epigenetics in Human Health and Disease Laboratory, Department of Diabetes, Central Clinical School, Monash University, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia., Karagiannis TC; Epigenomic Medicine Laboratory, Department of Diabetes, Central Clinical School, Monash University, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia. karat@unimelb.edu.au.; Department of Clinical Pathology, University of Melbourne, Parkville, VIC, 3010, Australia. karat@unimelb.edu.au.

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 Nov 01; Vol. 79 (11), pp. 579. Date of Electronic Publication: 2022 Nov 01.