Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Roya Rasaei"'
Autor:
Roya Rasaei, Apoorvi Tyagi, Shima Rasaei, Seung-Joon Lee, Se-Ran Yang, Kye-Seong Kim, Suresh Ramakrishna, Seok-Ho Hong
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Pulmonary fibrosis (PF) is a fatal chronic disease characterized by accumulation of extracellular matrix and thickening of the alveolar wall, ultimately leading to respiratory failure. PF is thought to be initiated by the dysfunction and abe
Externí odkaz:
https://doaj.org/article/bd411bb4f5d54fcab341650269f6fb6c
Autor:
Jung-Hyun Kim, Geun Ho An, Ji-Young Kim, Roya Rasaei, Woo Jin Kim, Xiong Jin, Dong-Hun Woo, Choongseong Han, Se-Ran Yang, Jong-Hoon Kim, Seok-Ho Hong
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Detailed understanding of the pathogenesis and development of effective therapies for pulmonary fibrosis (PF) have been hampered by lack of in vitro human models that recapitulate disease pathophysiology. In this study, we generated alveolar
Externí odkaz:
https://doaj.org/article/483430aa795245aa84ac8a0bb56e723f
Publikováno v:
Organoid, Vol 1 (2021)
Background Respiratory medicine has high barriers to new drug development, with fewer approved new treatments and candidate drugs and a higher failure rate than other common disease fields. Most of the major candidate drugs identified in preclinical
Externí odkaz:
https://doaj.org/article/47aebf09ee994900aa4f550f1c6bdfed
Autor:
Roya Rasaei, Eunbi Kim, Ji-Young Kim, Sunghun Na, Jung-Hyun Kim, Jinbeom Heo, Dong-Myung Shin, Sun Shim Choi, Seok-Ho Hong
Publikováno v:
Biomedicines, Vol 8, Iss 9, p 346 (2020)
Hyperglycemia is a causative factor in the pathogenesis of respiratory diseases, known to induce fibrosis and inflammation in the lung. However, little attention has been paid to genes related to hyperglycemic-induced lung alterations and stem cell a
Externí odkaz:
https://doaj.org/article/d83d44b279e0402993d4b2e06e6c09d2
Publikováno v:
Development & Reproduction
Diabetes mellitus is a common heterogeneous metabolic disorder, characterized by deposition of extracellular matrix, oxidative stress, and vascular dysfunction, thereby leading to gradual loss of function in multiple organs. However, little attention
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8090, p 8090 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Ubiquitination and deubiquitination play a fundamental role in the signaling pathways associated with innate and adaptive immune responses. Macrophages are key sentinels for the host defense, triggering antiviral and inflammatory responses against va