Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Roy Ronen"'
Autor:
Renata Duchnowska, Anna Maria Supernat, Rafał Pęksa, Marta Łukasiewicz, Tomasz Stokowy, Roy Ronen, Janusz Dutkowski, Monika Umińska, Ewa Iżycka-Świeszewska, Anna Kowalczyk, Waldemar Och, Monika Rucińska, Wojciech P. Olszewski, Tomasz Mandat, Bożena Jarosz, Michał Bieńkowski, Wojciech Biernat, Jacek Jassem
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Brain metastases (BMs) in ovarian cancer (OC) are a rare event. BMs occur most frequently in high-grade serous (HGS) OC. The molecular features of BMs in HGSOC are poorly understood. We performed a whole-exome sequencing analysis of ten matc
Externí odkaz:
https://doaj.org/article/d2d11a695913453e8ed1c77cf42a380f
Correction: Predicting Carriers of Ongoing Selective Sweeps without Knowledge of the Favored Allele.
Publikováno v:
PLoS Genetics, Vol 12, Iss 11, p e1006472 (2016)
[This corrects the article DOI: 10.1371/journal.pgen.1005527.].
Externí odkaz:
https://doaj.org/article/e8e165a15cdf4fb6832d104788a3f374
Publikováno v:
PLoS Genetics, Vol 11, Iss 9, p e1005527 (2015)
Methods for detecting the genomic signatures of natural selection have been heavily studied, and they have been successful in identifying many selective sweeps. For most of these sweeps, the favored allele remains unknown, making it difficult to dist
Externí odkaz:
https://doaj.org/article/a60a6ef717934d9f81eaac38cea0d44c
Publikováno v:
Cancers; Volume 14; Issue 18; Pages: 4532
Eribulin, a natural product-based microtubule targeting agent with cytotoxic and noncytotoxic mechanisms, is FDA approved for certain patients with advanced breast cancer and liposarcoma. To investigate the feasibility of developing drug-specific pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8cdd43f59f56ae8f041de6a245a87c9
Publikováno v:
Cancer Research. 83:LB176-LB176
Introduction: Immune Checkpoint Inhibition (ICI) therapies have demonstrated significant clinical success in multiple cancer types. However, many patients do not develop durable responses to ICI treatments and the underlying mechanisms of action are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ca65021b45494f0b0aba62a6d8e36ec
https://doi.org/10.1158/1538-7445.am2023-lb176
https://doi.org/10.1158/1538-7445.am2023-lb176
Autor:
Kimberly A. Burton, Elisabeth Mahen, Eric Quentin Konnick, Sibel Blau, Michael O. Dorschner, Arturo B. Ramirez, Stephen C. Schmechel, Chaozhong Song, Rahul Parulkar, Stephanie Parker, Francis Mark Senecal, Colin C. Pritchard, Brigham H. Mecham, Christopher Szeto, Patricia Spilman, Jingchun Zhu, Vijayakrishna K. Gadi, Roy Ronen, Jackie Stilwell, Eric Kaldjian, Janusz Dutkowski, Stephen Charles Benz, Shahrooz Rabizadeh, Patrick Soon-Shiong, C. Anthony Blau
Publikováno v:
JCO Precision Oncology.
PURPOSE Patients with metastatic triple-negative breast cancer (mTNBC) have poor outcomes. The Intensive Trial of Omics in Cancer (ITOMIC) sought to determine the feasibility and potential efficacy of informing treatment decisions through multiple bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143431466f537651c2ca6a73977557ae
https://doi.org/10.1200/po.21.00280
https://doi.org/10.1200/po.21.00280
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e480cd1ba246fc29fca41dc4381d6403
https://doi.org/10.1002/alz.053842
https://doi.org/10.1002/alz.053842
Publikováno v:
Cancer Research. 82:LB148-LB148
Background: Effective target discovery strategies are key to developing new precision medicines against cancer. Large-scale efforts to systematically characterize cancer-associated germline variants, genomic changes in tumors and cancer genetic depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d48bcf411ebf3abb253f562e05327928
https://doi.org/10.1158/1538-7445.am2022-lb148
https://doi.org/10.1158/1538-7445.am2022-lb148
Autor:
Yu Hsin Hsiao, Vineet Bafna, Dan Zhou, Gabriel G. Haddad, Roy Ronen, Orit Poulsen, Huiwen W. Zhao, Otto Appenzeller, Pedro Cabrales, Priti Azad
Publikováno v:
The Journal of Experimental Medicine
Azad and collaborators propose that Senp1 drives excessive erythropoiesis in high-altitude Andean dwellers suffering from chronic mountain sickness.
In this study, because excessive polycythemia is a predominant trait in some high-altitude dwell
In this study, because excessive polycythemia is a predominant trait in some high-altitude dwell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c6589487e75f8d9c36e9d75f13986f
http://europepmc.org/articles/PMC5110013
http://europepmc.org/articles/PMC5110013
Publikováno v:
Cancer Research. 80:1924-1924
Background: Eribulin mesylate, a synthetic analog of the marine sponge natural product halichondrin B, is a microtubule dynamics inhibitor that acts via both cytotoxic antimitotic mechanisms as well as non-cytotoxic effects on tumor vasculature, tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea31d7f86c48e2002887b365128ed17e
https://doi.org/10.1158/1538-7445.am2020-1924
https://doi.org/10.1158/1538-7445.am2020-1924