Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Roy Riblet"'
Autor:
Mandy M. Peak, Frank Grosveld, Steve Cutchin, Cornelis Murre, Menno C. van Zelm, Jacques J.M. van Dongen, Tobias Knoch, Suchit Jhunjhunwala, Roy Riblet
Publikováno v:
Cell, 133(2), 265-279. Cell Press
The immunoglobulin heavy-chain (Igh) locus is organized into distinct regions that contain multiple variable (V(H)), diversity (D(H)), joining (J(H)) and constant (C(H)) coding elements. How the Igh locus is structured in 3D space is unknown. To prob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090783335d5d79201760421295407eab
https://doi.org/10.1016/j.cell.2008.03.024
https://doi.org/10.1016/j.cell.2008.03.024
Autor:
Gabriele Nordsiek, Martin Hafner, America Mauhar, Ansgar Conrad, Monika Ludewig, Simone Severitt, Stephanie Thies, Werner Müller, Maren Scharfe, Tschong Hun Im, Helmut Blöcker, Roy Riblet, Christophe Chevillard, Ida Retter
Publikováno v:
Scopus-Elsevier
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2007, 179 (4), pp.2419-2427
Europe PubMed Central
Journal of Immunology, 2007, 179 (4), pp.2419-2427
ResearcherID
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2007, 179 (4), pp.2419-2427
Europe PubMed Central
Journal of Immunology, 2007, 179 (4), pp.2419-2427
ResearcherID
Although the entire mouse genome has been sequenced, there remain challenges concerning the elucidation of particular complex and polymorphic genomic loci. In the murine Igh locus, different haplotypes exist in different inbred mouse strains. For exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465f0cae2c52b90f4c8fec72fcc31b44
https://doi.org/10.4049/jimmunol.179.4.2419
https://doi.org/10.4049/jimmunol.179.4.2419
The temporal and lineage specificity of antigen receptor assembly is regulated at multiple levels. These include locus conformation, germline transcription, chromatin remodeling, epigenetic marking, and nuclear location. Here we discuss how the immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::301d0411d2085302fb0262285ae708a1
https://doi.org/10.1016/b978-0-12-397933-9.00001-1
https://doi.org/10.1016/b978-0-12-397933-9.00001-1
Autor:
Frederick W. Alt, Radbruch Andreas, Nasim A. Begum, Michael C. Carroll, Andrea Cerutti, Richard Chahwan, Tsutomu Chiba, Max D. Cooper, Riccardo Dalla-Favera, Van Duc Dang, Sabyasachi Das, Betty Diamond, Anne Durandy, Sidonia Fagarasan, Ann J. Feeney, Marc Feldmann, Simon Fillatreau, Alain Fischer, Jennifer L. Gommerman, Carl S. Goodyear, James Hagman, Richard R. Hardy, Anja E. Hauser, Kyoko Hayakawa, Barton F. Haynes, Brantley R. Herrin, Falk Hiepe, Masaki Hikida, Ellen Hilgenberg, Masayuki Hirano, Tasuku Honjo, Uta E. Höpken, Ellen Hsu, Hassan Jumaa, John F. Kearney, Garnett Kelsoe, Tadamitsu Kishimoto, Maki Kobayashi, Sven Kracker, Tomohiro Kurosaki, Marie-Paule Lefranc, Susanna M. Lewis, Jianxu Li, Andreia C. Lino, Alicia J. Little, Joseph S. Lucas, Fabienne Mackay, Giuliana Magri, Alberto Martin, Hiroyuki Marusawa, John R. Mascola, Adam Matthews, Iain B. McInnes, Fei-Long Meng, Byoung-Gon Moon, Stefan A. Muljo, Cornelis Murre, Gary J. Nabel, Hitoshi Nagaoka, Masashi Narazaki, Falk Nimmerjahn, Lars Nitschke, Alberto Nobrega, Marjorie Oettinger, Jahan Yar Parsa, Laura Pasqualucci, Klaus Rajewsky, Jeffrey V. Ravetch, Michael Reth, Roy Riblet, Stefanie Ries, David B. Roth, Imme Sakwa, Kevin O. Saunders, Matthew D. Scharff, David G. Schatz, Harry W. Schroeder, Ping Shen, Susan A. Shinton, Akritee Shrestha, Yoichi Sutoh, Atsushi Takai, Toshitada Takemori, Toshio Tanaka, David Tarlinton, Ming Tian, Alexander Tsoukas, Andre M. Vale, Markus Werner, Duane R. Wesemann, Yan Zhou, Yong-Rui Zou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf99d027c33d94e20476dd76e01188c4
https://doi.org/10.1016/b978-0-12-397933-9.01002-x
https://doi.org/10.1016/b978-0-12-397933-9.01002-x
Autor:
Christina V. Angeles, Peter H. Brodeur, Inka Pawlitzky, Andrea M. Siegel, Michelle L. Stanton, Roy Riblet
Publikováno v:
The Journal of Immunology. 176:6839-6851
The Igh locus is controlled by cis-acting elements, including Eμ and the 3′ IgH regulatory region which flank the C region genes within the well-studied 3′ part of the locus. Although the presence of additional control elements has been postulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88734fd7d549f9cd4bfee5370a2948fe
https://doi.org/10.4049/jimmunol.176.11.6839
https://doi.org/10.4049/jimmunol.176.11.6839
Publikováno v:
Molecular and Cellular Biology. 25:6021-6030
VDJ rearrangement in the mouse immunoglobulin heavy chain (Igh) locus involves a combination of events, including a large change in its nuclear compartmentalization. Prior to rearrangement, Igh moves from its default peripheral location near the nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e488bca62c12ec749c611434da91836
https://doi.org/10.1128/mcb.25.14.6021-6030.2005
https://doi.org/10.1128/mcb.25.14.6021-6030.2005
Publikováno v:
Immunogenetics. 55:80-86
Previous studies demonstrated that the diversity of the antibody response of mice to the inulin (In) determinant of bacterial levan is regulated by the gene Spectrotype Regulation 1 ( Sr1). BALB/c mice produce a monoclonal anti-In response as shown b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f238de8a24586cc4055d1a59bf39489
https://doi.org/10.1007/s00251-003-0555-z
https://doi.org/10.1007/s00251-003-0555-z
Publikováno v:
Molecular and Cellular Biology. 22:4876-4889
In Saccharomyces cerevisiae, the initiation of DNA replication is sequence specific (27; for a review, see reference 23). In mammalian cells, however, the mechanism underlying this process is still being defined. Although specific origins of replicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ef925b8198a4debde17b00c3f10190
https://doi.org/10.1128/mcb.22.13.4876-4889.2002
https://doi.org/10.1128/mcb.22.13.4876-4889.2002
Ig Heavy Chain Complex-Linked Genes Influence the Immune Response in a Murine Cryptococcal Infection
Autor:
Julie A. Lovchik, Julie A. Wilder, Gary B. Huffnagle, Roy Riblet, C. Richard Lyons, Mary F. Lipscomb
Publikováno v:
The Journal of Immunology. 163:3907-3913
A murine pulmonary infection with Cryptococcus neoformans (Cne) has been used to determine mechanisms regulating effective T cell-mediated immunity in the lungs. In BALB/c and C.B-17 mice, following intratracheal deposition of Cne, the fungus initial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20006e0be4493f9eaaa6791f4db304a9
https://doi.org/10.4049/jimmunol.163.7.3907
https://doi.org/10.4049/jimmunol.163.7.3907
Autor:
Roy Riblet, Christa E. Müller-Sieburg
Publikováno v:
The Journal of Experimental Medicine
The genetic elements that govern the differentiation and proliferation of hematopoietic stem cells remain to be defined. We describe here marked strain-specific differences in the frequency of long-term culture-initiating cells (LTC-IC) in the bone m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9a1caf20a811d40abf5eece9ba68e5
https://doi.org/10.1084/jem.183.3.1141
https://doi.org/10.1084/jem.183.3.1141