Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Roy R. Hantgan"'
Autor:
John T. Melchior, Janet K. Sawyer, Kathryn L. Kelley, Ramesh Shah, Martha D. Wilson, Roy R. Hantgan, Lawrence L. Rudel
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 9, Pp 2495-2503 (2013)
Several studies in humans and animals suggest that LDL particle core enrichment in cholesteryl oleate (CO) is associated with increased atherosclerosis. Diet enrichment with MUFAs enhances LDL CO content. Steroyl O-acyltransferase 2 (SOAT2) is the en
Externí odkaz:
https://doaj.org/article/e6cc634aeed2400a97574b2b5a36f6e9
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 2, Pp 211-217 (2001)
Apolipoprotein (apo)A-IV is synthesized in the small intestine during fat absorption and is incorporated onto the surface of nascent chylomicrons. In circulation, apoA-IV is displaced from the chylomicron surface by high density lipoprotein-associate
Externí odkaz:
https://doaj.org/article/d444d91cb9b84de6871013f799b4436e
Autor:
Philip J Smaldino, Eric D Routh, Jung H Kim, Banabihari Giri, Steven D Creacy, Roy R Hantgan, Steven A Akman, James P Vaughn
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132668 (2015)
Ends of human chromosomes consist of the six nucleotide repeat d[pTTAGGG]n known as telomeric DNA, which protects chromosomes. We have previously shown that the DHX36 gene product, G4 Resolvase 1 (G4R1), binds parallel G-quadruplex (G4) DNA with an u
Externí odkaz:
https://doaj.org/article/a197ea1e19fe44bc874be96b8aff12ca
Autor:
Travis J Riedel, Lynnette C Johnson, John Knight, Roy R Hantgan, Ross P Holmes, W Todd Lowther
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26021 (2011)
4-hydroxy-2-oxoglutarate (HOG) aldolase is a unique enzyme in the hydroxyproline degradation pathway catalyzing the cleavage of HOG to pyruvate and glyoxylate. Mutations in this enzyme are believed to be associated with the excessive production of ox
Externí odkaz:
https://doaj.org/article/c240ed0aa19144a8b5b3d254279b01cc
Autor:
Mark T. Gladwin, Juan J Lertora, Roy R. Hantgan, H. Shaw Warren, Kenneth E. Remy, Irene Cortés-Puch, Benjamin M Pockros, Xiaohua Liu, Junfeng Sun, Charles Natanson, Andreas Perlegas, Jing Feng, Harvey G. Klein, Steven B. Solomon, Daniel B. Kim-Shapiro
Publikováno v:
JCI insight. 3(18)
During the last half-century, numerous antiinflammatory agents were tested in dozens of clinical trials and have proven ineffective for treating septic shock. The observation in multiple studies that cell-free hemoglobin (CFH) levels are elevated dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4b39bfa8f690048432fe070c1fafcf
https://pubmed.ncbi.nlm.nih.gov/30232287
https://pubmed.ncbi.nlm.nih.gov/30232287
Autor:
Simon Lattmann, Eric D. Routh, Steven A. Akman, Ryan G. Thys, James P. Vaughn, Banabihari Giri, Roy R. Hantgan, Steven D. Creacy, Philip J. Smaldino, Yoshikuni Nagamine
Publikováno v:
Nucleic Acids Research
It has been previously shown that the DHX36 gene product, G4R1/RHAU, tightly binds tetramolecular G4-DNA with high affinity and resolves these structures into single strands. Here, we test the ability of G4R1/RHAU to bind and unwind unimolecular G4-D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2a62d3e7a91b06e87a8fdd0a1de863
http://doc.rero.ch/record/291105/files/gkr234.pdf
http://doc.rero.ch/record/291105/files/gkr234.pdf
Autor:
Yehuda Goldgur, Sara Ferluga, Roy R. Hantgan, Juha P. Himanen, Dimitar B. Nikolov, Waldemar Debinski
Publikováno v:
Journal of Biological Chemistry. 288:18448-18457
The EphA2 receptor tyrosine kinase is overexpressed in a number of malignancies and is activated by ephrin ligands, most commonly by ephrin-A1. The crystal structure of the ligand-receptor complex revealed a glycosylation on the Asn-26 of ephrin-A1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9924d14ad92f2ec191d06b11e9f1fbee
https://doi.org/10.1074/jbc.m113.464008
https://doi.org/10.1074/jbc.m113.464008
Publikováno v:
Biomaterials. 34:2492-2500
Uncontrolled bleeding continues to be one of the leading causes of death in individuals following traumatic injury. Prognosis is worsened with the onset of acute coagulopathy characterized by metabolic acidosis, hypothermia and hemodilution, which co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0ddbcdb1c88849ef565b85186d414a
https://doi.org/10.1016/j.biomaterials.2012.12.008
https://doi.org/10.1016/j.biomaterials.2012.12.008
Autor:
Caroline E. Bass, Lawrence C. Blume, Theresa Patten, Khalil Eldeeb, Alexander A. Ilyasov, Sandra Leone-Kabler, W. Todd Lowther, Allyn C. Howlett, Dana E. Selley, Roy R. Hantgan, Jeremy E. O’Neal, Bradley M Keegan
Publikováno v:
Molecular pharmacology. 91(2)
Cannabinoid receptor interacting protein 1a (CRIP1a) is a CB1 receptor (CB1R) distal C-terminal-associated protein that alters CB1R interactions with G-proteins. We tested the hypothesis that CRIP1a is capable of also altering CB1R interactions with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66c7ee74a6c7b487713ef082966576c
https://pubmed.ncbi.nlm.nih.gov/27895162
https://pubmed.ncbi.nlm.nih.gov/27895162
Autor:
Roy R. Hantgan, Martin Guthold, David L. Carroll, Christine R. Carlisle, Corentin Coulais, Manoj A. G. Namboothiry
Publikováno v:
Biomaterials. 30:1205-1213
We used a combined atomic force microscopic (AFM)/fluorescence microscopic technique to study the mechanical properties of individual, electrospun fibrinogen fibers in aqueous buffer. Fibers (average diameter 208 nm) were suspended over 12 microm-wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f6b6dfa93519d7b46be42ea8910821
https://doi.org/10.1016/j.biomaterials.2008.11.006
https://doi.org/10.1016/j.biomaterials.2008.11.006