Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Roy R Chaudhuri"'
Autor:
Jessica E Buddle, Lucy M Thompson, Anne S Williams, Rosanna C T Wright, William M Durham, Claire E Turner, Roy R Chaudhuri, Michael A Brockhurst, Robert P Fagan
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002741 (2024)
Clostridioides difficile is an important human pathogen, for which there are very limited treatment options, primarily the glycopeptide antibiotic vancomycin. In recent years, vancomycin resistance has emerged as a serious problem in several gram-pos
Externí odkaz:
https://doaj.org/article/53a85d31ba3c433588634f1cb67da377
Autor:
Michael J Ormsby, Filipa Vaz, Joseph A Kirk, Anna Barwinska-Sendra, Jennifer C Hallam, Paola Lanzoni-Mangutchi, John Cole, Roy R Chaudhuri, Paula S Salgado, Robert P Fagan, Gillian R Douce
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011015 (2023)
Clostridioides difficile is responsible for substantial morbidity and mortality in antibiotically-treated, hospitalised, elderly patients, in which toxin production correlates with diarrhoeal disease. While the function of these toxins has been studi
Externí odkaz:
https://doaj.org/article/29ae89a68e0640afb2755f72cda25492
Autor:
Saikou Y. Bah, Alexander J. Keeley, Edwin P. Armitage, Henna Khalid, Roy R. Chaudhuri, Elina Senghore, Jarra Manneh, Lisa Tilley, Michael Marks, Saffiatou Darboe, Abdul K. Sesay, Thushan I. de Silva, Claire E. Turner
Publikováno v:
mSphere, Vol 8, Iss 1 (2023)
ABSTRACT Streptococcus pyogenes is a leading cause of human morbidity and mortality, especially in resource-limited settings. The development of a vaccine against S. pyogenes is a global health priority to reduce the burden of postinfection rheumatic
Externí odkaz:
https://doaj.org/article/777bbb6398cb4b4ebf4d266b1482a0aa
Autor:
Janine T. Bossé, Yanwen Li, Leon G. Leanse, Liqing Zhou, Roy R. Chaudhuri, Sarah E. Peters, Jinhong Wang, Gareth A. Maglennon, Matthew T. G. Holden, Duncan J. Maskell, Alexander W. Tucker, Brendan W. Wren, Andrew N. Rycroft, Paul R. Langford, on behalf of the BRaDP1T consortium
Publikováno v:
Animal Diseases, Vol 1, Iss 1, Pp 1-13 (2021)
Abstract Comprehensive identification of conditionally essential genes requires efficient tools for generating high-density transposon libraries that, ideally, can be analysed using next-generation sequencing methods such as Transposon Directed Inser
Externí odkaz:
https://doaj.org/article/f094b55991ac4fa1b5e1c9c4b524d061
Autor:
Prerna Vohra, Roy R. Chaudhuri, Matthew Mayho, Christina Vrettou, Cosmin Chintoan-Uta, Nicholas R. Thomson, Jayne C. Hope, John Hopkins, Mark P. Stevens
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Salmonella enterica subspecies enterica is an animal and zoonotic pathogen of global importance. Cattle are a significant reservoir of human non-typhoidal salmonellosis and can suffer enteric and systemic disease owing to the abil
Externí odkaz:
https://doaj.org/article/02f510ff6f364fa7bb56ddb2ab716d4c
Extensive microbial diversity within the chicken gut microbiome revealed by metagenomics and culture
Autor:
Rachel Gilroy, Anuradha Ravi, Maria Getino, Isabella Pursley, Daniel L. Horton, Nabil-Fareed Alikhan, Dave Baker, Karim Gharbi, Neil Hall, Mick Watson, Evelien M. Adriaenssens, Ebenezer Foster-Nyarko, Sheikh Jarju, Arss Secka, Martin Antonio, Aharon Oren, Roy R. Chaudhuri, Roberto La Ragione, Falk Hildebrand, Mark J. Pallen
Publikováno v:
PeerJ, Vol 9, p e10941 (2021)
Background The chicken is the most abundant food animal in the world. However, despite its importance, the chicken gut microbiome remains largely undefined. Here, we exploit culture-independent and culture-dependent approaches to reveal extensive tax
Externí odkaz:
https://doaj.org/article/dc7b5c757c144038be37319f7d5322be
Autor:
Thamarai K. Janganan, Nic Mullin, Ainhoa Dafis-Sagarmendi, Jason Brunt, Svetomir B. Tzokov, Sandra Stringer, Anne Moir, Roy R. Chaudhuri, Robert P. Fagan, Jamie K. Hobbs, Per A. Bullough
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT Spores, the infectious agents of many Firmicutes, are remarkably resilient cell forms. Even distant relatives can have similar spore architectures although some display unique features; they all incorporate protective proteinaceous envelopes
Externí odkaz:
https://doaj.org/article/41d109989bd9469a8966c01fd5b8668e
Autor:
Rocío Canals, Roy R Chaudhuri, Rebecca E Steiner, Siân V Owen, Natalia Quinones-Olvera, Melita A Gordon, Michael Baym, Michael Ibba, Jay C D Hinton
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1007948 (2019)
We have used a transposon insertion sequencing (TIS) approach to establish the fitness landscape of the African Salmonella enterica serovar Typhimurium ST313 strain D23580, to complement our previous comparative genomic and functional transcriptomic
Externí odkaz:
https://doaj.org/article/b2d83a68e52043c9a34d009f7e7e3d08
Autor:
Calum A. Pattrick, Joseph P. Webb, Jeffrey Green, Roy R. Chaudhuri, Mark O. Collins, David J. Kelly
Publikováno v:
mSystems, Vol 4, Iss 4 (2019)
ABSTRACT Vanillin (4-hydroxy-3-methoxybenzaldehyde) is an economically important flavor compound that can be made in bacterial cell factories, but toxicity is a major problem for cells producing this aromatic aldehyde. Using (i) a global proteomic an
Externí odkaz:
https://doaj.org/article/10c3d95be6f54fd59c67de743b7d24dd
Autor:
Rocío Canals, Disa L Hammarlöf, Carsten Kröger, Siân V Owen, Wai Yee Fong, Lizeth Lacharme-Lora, Xiaojun Zhu, Nicolas Wenner, Sarah E Carden, Jared Honeycutt, Denise M Monack, Robert A Kingsley, Philip Brownridge, Roy R Chaudhuri, Will P M Rowe, Alexander V Predeus, Karsten Hokamp, Melita A Gordon, Jay C D Hinton
Publikováno v:
PLoS Biology, Vol 17, Iss 1, p e3000059 (2019)
Salmonella Typhimurium sequence type (ST) 313 causes invasive nontyphoidal Salmonella (iNTS) disease in sub-Saharan Africa, targeting susceptible HIV+, malarial, or malnourished individuals. An in-depth genomic comparison between the ST313 isolate D2
Externí odkaz:
https://doaj.org/article/31ec980307d14f1684f15b5ba899d49a