Zobrazeno 1 - 10
of 9 071
pro vyhledávání: '"Roy N"'
Autor:
Ofir Sade, Daphna Fischel, Noa Barak-Broner, Shir Halevi, Irit Gottfried, Dana Bar-On, Stefan Sachs, Anat Mirelman, Avner Thaler, Aviv Gour, Meir Kestenbaum, Mali Gana Weisz, Saar Anis, Claudio Soto, Melanie Shanie Roitman, Shimon Shahar, Kathrin Doppler, Markus Sauer, Nir Giladi, Nirit Lev, Roy N. Alcalay, Sharon Hassin-Baer, Uri Ashery
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Alpha-synuclein (aSyn) aggregates in the central nervous system are the main pathological hallmark of Parkinson’s disease (PD). ASyn aggregates have also been detected in many peripheral tissues, including the skin, thus providing a novel and acces
Externí odkaz:
https://doaj.org/article/fb9c6cb2b32745928068125ebd86b591
Autor:
Stephen Weber, Kelly B. Menees, Jieun Park, Julian Agin-Liebes, Chih-Chun Lin, Roy N. Alcalay, Jae-Kyung Lee
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Mounting data suggest an important role for the immune system in Parkinson’s disease (PD). Previous evidence of increased natural killer (NK) cell populations in PD suggests a potential role of NK cells in the pathogenesis of the disease.
Externí odkaz:
https://doaj.org/article/a402035f904947c891211efc4e6ed5ec
Autor:
Yahaira Naaldijk, Belén Fernández, Rachel Fasiczka, Elena Fdez, Coline Leghay, Ioana Croitoru, John B. Kwok, Yanisse Boulesnane, Amelie Vizeneux, Eugenie Mutez, Camille Calvez, Alain Destée, Jean-Marc Taymans, Ana Vinagre Aragon, Alberto Bergareche Yarza, Shalini Padmanabhan, Mario Delgado, Roy N. Alcalay, Zac Chatterton, Nicolas Dzamko, Glenda Halliday, Javier Ruiz-Martínez, Marie-Christine Chartier-Harlin, Sabine Hilfiker
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Parkinson´s disease (PD) is a common neurodegenerative movement disorder and leucine-rich repeat kinase 2 (LRRK2) is a promising therapeutic target for disease intervention. However, the ability to stratify patients who will benefit from su
Externí odkaz:
https://doaj.org/article/c64a6d54ee0f438bada89215f582520b
Autor:
Bryony S. Tucker, Maria Jorquera-Chavez, Kiro R. Petrovski, Jessica R. Craig, Rebecca S. Morrison, Robert J. Smits, Roy N. Kirkwood
Publikováno v:
Journal of Applied Animal Research, Vol 51, Iss 1, Pp 212-219 (2023)
Surface temperature recording has shown promise in older pigs and in piglets but only under controlled conditions. The aim of this experiment was to compare surface temperatures using an infrared thermal camera (pointer), verified by the maximum temp
Externí odkaz:
https://doaj.org/article/d047420a797146a48e21d94e44659a82
Autor:
Egie E. Enabulele, Winka Le Clec’h, Emma K. Roberts, Cody W. Thompson, Molly M. McDonough, Adam W. Ferguson, Robert D. Bradley, Timothy J. C. Anderson, Roy N. Platt
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 8, Pp 1566-1579 (2023)
More than 60 zoonoses are linked to small mammals, including some of the most devastating pathogens in human history. Millions of museum-archived tissues are available to understand natural history of those pathogens. Our goal was to maximize the val
Externí odkaz:
https://doaj.org/article/acd864c5ed8946bcabd159d8b11caa46
Autor:
Yosua Kristian Adi, Preechaphon Taechamaeteekul, Sawang Kesdangsakonwut, Paisan Tienthai, Roy N. Kirkwood, Padet Tummaruk
Publikováno v:
Animals, Vol 14, Iss 13, p 1846 (2024)
This study investigated the gross morphology of reproductive organs and oxytocin receptor distribution across different parities in hyperprolific sows. A total of thirty-two reproductive organs from Landrace × Yorkshire crossbred sows were categoriz
Externí odkaz:
https://doaj.org/article/cb0246b80c394cc799c7362f7e9f2af2
Autor:
Bonnie Homer, Reza Barekatain, Kiro R. Petrovski, Kate J. Plush, Corinna Dwan, Darryl N. D’Souza, Paul J. Verma, Roy N. Kirkwood, Bryony S. Tucker
Publikováno v:
Animals, Vol 14, Iss 10, p 1472 (2024)
Weaning stress imposes considerable physiological challenges on piglets, often manifesting in intestinal disturbances, such as inflammation and compromised barrier function, ultimately affecting growth and health outcomes. While conventional interven
Externí odkaz:
https://doaj.org/article/425bd9e9e25c4df29be745fc4b6fa1fc
Autor:
Marco Hadisurya, Li Li, Kananart Kuwaranancharoen, Xiaofeng Wu, Zheng-Chi Lee, Roy N. Alcalay, Shalini Padmanabhan, W. Andy Tao, Anton Iliuk
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-19 (2023)
Abstract Background Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been recognized as genetic risk factors for Parkinson’s disease (PD). However, compared to cancer, fewer genetic mutations contribute to the cause of PD, propelling
Externí odkaz:
https://doaj.org/article/bb715f3f213548718f0eb37825217e71
Autor:
Hash Brown Taha, Simon Hornung, Suman Dutta, Leony Fenwick, Otmane Lahgui, Kathryn Howe, Nour Elabed, Irish del Rosario, Darice Y. Wong, Aline Duarte Folle, Daniela Markovic, Jose-Alberto Palma, Un Jung Kang, Roy N. Alcalay, Miriam Sklerov, Horacio Kaufmann, Brent L. Fogel, Jeff M. Bronstein, Beate Ritz, Gal Bitan
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/85fb98a9deb841f7a68e9dae119d15cf
Autor:
Kalpana M. Merchant, Tanya Simuni, Janel Fedler, Chelsea Caspell-Garcia, Michael Brumm, Kelly N. H. Nudelman, Elizabeth Tengstrandt, Frank Hsieh, Roy N. Alcalay, Christopher Coffey, Lana Chahine, Tatiana Foroud, Andrew Singleton, Daniel Weintraub, Samantha Hutten, Todd Sherer, Brit Mollenhauer, Andrew Siderowf, Caroline Tanner, Ken Marek, the Parkinson’s Progression Markers Initiative
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract We quantified concentrations of three isoforms of the endolysosomal lipid, bis(monoacylglycerol) phosphate (BMP) in the urine of deeply phenotyped cohorts in the Parkinson’s Progression Markers Initiative: LRRK2 G2019S PD (N = 134) and non
Externí odkaz:
https://doaj.org/article/674e487ec4e94ab582d9d5a390d1a79e