Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Roy M. Smeal"'
Autor:
J. Michael eGee, Meredith B. Gibbons, Marsa eTaheri, Sierra ePalumbos, S. Craig eMorris, Roy M. Smeal, Katherine F. Flynn, Michael N. Economo, Christian G. Cizek, Mario R. Capecchi, Petr eTvrdik, Karen S. Wilcox, John A. White
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 8 (2015)
Complex interactions between networks of astrocytes and neurons are beginning to be appreciated, but remain poorly understood. Transgenic mice expressing fluorescent protein reporters of cellular activity, such as the GCaMP family of genetically enco
Externí odkaz:
https://doaj.org/article/3807f5026071472590f4793874944f74
Autor:
John A. White, Maria E. Rubio, Roy M. Smeal, Karen S. Wilcox, Cheryl Clarkson, Meredith G. Hasenoehrl
Publikováno v:
Experimental Neurology. 326:113196
The persistent unresponsiveness of many of the acquired epilepsies to traditional antiseizure medications has motivated the search for prophylactic drug therapies that could reduce the incidence of epilepsy in this at risk population. These studies a
Autor:
Dipan C. Patel, Pallavi B. McElroy, Kyle E. Thomson, Karen S. Wilcox, David E. Szymkowski, Manisha Patel, E. Jill Dahle, Peter J. West, Raymond J. Tesi, Glenna J. Wallis, Roy M. Smeal, H. Steve White, Robert S. Fujinami
Publikováno v:
eNeuro
Central nervous system infection can induce epilepsy that is often refractory to established antiseizure drugs. Previous studies in the Theiler’s murine encephalomyelitis virus (TMEV)-induced mouse model of limbic epilepsy have demonstrated the imp
Autor:
Patrick A. Tresco, Roy M. Smeal
Publikováno v:
Experimental Neurology. 213:281-292
Damage to axonal tracts of the central nervous system results in costly and permanent disability. The observations of aborted neurite outgrowth and disorganized scarring in injured central nervous system tissue have motivated the hypothesis that engi
Publikováno v:
Journal of Neuroscience Methods. 159:224-235
The striatum, the primary input nucleus of the basal ganglia, is crucially involved in motor and cognitive function and receives significant glutamate input from the cortex and thalamus. Increasing evidence suggests fundamental differences between th
Publikováno v:
Neuroscience letters. 609
Viral infections of the central nervous system are often associated with seizures, and while patients usually recover from the infection and the seizures cease, there is an increased lifetime incidence of epilepsy. These viral infections can result i
Publikováno v:
Annals of Biomedical Engineering. 33:376-382
Nerve outgrowth in the developing nervous system utilizes a variety of attractive and repulsive molecules found in the extracellular environment. In addition, physical cues may play an important regulatory role in determining directional outgrowth of
Publikováno v:
Neurochemistry international. 63(7)
Status epilepticus (SE) is a life threatening condition that often precedes the development of epilepsy. Traditional treatments for epilepsy have been focused on targeting neuronal mechanisms contributing to hyperexcitability, however, approximately
Publikováno v:
Journal of Bioengineering & Biomedical Science.
Attention is being increasingly focused on the dynamical behavior of large networks of neurons and astrocytes and the changes in these dynamics that occur during the progression of diseases like epilepsy. Recording from large numbers of identified ce
We review the principal assumptions underlying the application of phase-response curves (PRCs) to synchronization in neuronal networks. The PRC measures how much a given synaptic input perturbs spike timing in a neural oscillator. Among other applica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27a7e057b09c89c36452f44ba94ca28
https://europepmc.org/articles/PMC2894948/
https://europepmc.org/articles/PMC2894948/