Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Roy L. Williams"'
Publikováno v:
Journal of Cardiovascular Pharmacology. 40:399-410
Phytoestrogens have been shown to inhibit platelet activation by blocking platelet calcium channels. This study examined the effect of several synthetic derivatives of trans-resveratrol, genistein, and daidzein on platelet free intracellular calcium
Publikováno v:
The Prostate. 52:319-329
BACKGROUND This study was conducted to determine the effects of resveratrol on prostate cancer cell viability through apoptosis induction and the significance of the three hydroxyl groups on resveratrol to the measured effect. METHODS Hormone-sensiti
Publikováno v:
Journal of Chromatographic Science. 39:321-324
This study addresses the question of whether the antibiotic Penicillin, which is produced by the common mold Penicillium notatum, could possibly become a contaminate of wine during the fermentation process. The significance of this study is related t
Publikováno v:
British Journal of Pharmacology. 128:149-157
1. The phytoestrogenic compound trans-resveratrol (trans-3,5, 4'-trihydroxystilbene) is found in appreciable quantities in grape skins and wine. It has been shown that both products rich in trans-resveratrol and pure trans-resveratrol inhibit platele
Publikováno v:
Journal of Wine Research. 7:25-31
Reports regarding the positive health effects associated with the moderate consumption of red wine continue to be reinforced in the current scientific literature. These observations have prompted our laboratory to investigate the development of a whi
Autor:
Beth Dovel, Yuliya Dobrydneva, Christopher J. Abelt, Roy L. Williams, Peter F. Blackmore, Celina M. Thadigiri
Publikováno v:
Molecular pharmacology. 69(1)
We have synthesized a series of 2-aminoethoxydiphenyl borate (2-APB, 2,2-diphenyl-1,3,2-oxazaborolidine) analogs and tested their ability to inhibit thrombin-induced Ca(2+) influx in human platelets. The analogs were either synthesized by adding vari
Publikováno v:
Chirality. 15(8)
A high-affinity ligand for the type II estrogen binding site (EBS) was identified. Methyl para-hydroxyphenyllactate (MeHPLA) was observed to suppress the cellular proliferation of estrogen-sensitive MCF-7 breast cancer cells in vitro and to suppress
Autor:
Yuliya Dobrydneva, Roy L. Williams, Peter F. Blackmore, John A. Katzenellenbogen, Paul H. Ratz
Publikováno v:
Thrombosis research. 110(1)
The effects of compounds with the stilbene pharmacophore [diethylstilbestrol (DES), DES derivatives, tetrahydrochrysene (THC), and THC derivatives] were examined for their ability to inhibit thrombin-induced Ca(2+) influx in human platelets. DES deri
Autor:
S. W. Shalaby, Roy L. Williams
Publikováno v:
Journal of Heterocyclic Chemistry. 10:891-898
The synthesis and reactions of dimethyl 3, 4- and 4, 5-diaminophthalate 7 and 9 were investigated. The condensation of these isomeric diaminophthalates and their respective nitroacetamido precursors have been shown to give rise to a variety of five,
Autor:
Keisuke Kurita, Roy L. Williams
Publikováno v:
Journal of Polymer Science: Polymer Chemistry Edition. 11:3151-3160
Polyamide-amic acids containing bipyridyl units were prepared by polymerization of various bipyridyl diamines with trimellitic anhydride acid chloride. These polymers were converted to polyamide-imides by thermal cyclization. The resulting polyamide-