Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Roy L. M. Dobson"'
Autor:
Donald L. Bjerke, Rui Li, Jason M. Price, Roy L. M. Dobson, MyriamRubecca Rodrigues, ChingSiang Tey, Laura Vires, Rachel L. Adams, Joseph D. Sherrill, Peter B. Styczynski, Kirsty Goncalves, Victoria Maltman, Stefan Przyborski, John E. Oblong
Publikováno v:
Experimental Dermatology. 30
Autor:
G. Frank Gerberick, Cindy A. Ryan, Thomas M Burt, John A. Troutman, Petra S. Kern, Roy L. M. Dobson, Hong Jian Dai, Mike Quijano
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 178(1)
A peptide reactivity assay with an activation component was developed for use in screening chemicals for skin sensitization potential. A horseradish peroxidase-hydrogen peroxide (HRP/P) oxidation system was incorporated into the assay for characteriz
Autor:
John Erich Oblong, Stefan Przyborski, Victoria Maltman, Roy L. M. Dobson, Donald L. Bjerke, Rui Li, Kirsty Goncalves, Joseph D. Sherrill, Jason M. Price, MyriamRubecca Rodrigues, Laura Vires, ChingSiang Tey, Rachel L. Adams, Peter B. Styczynski
Human skin is exposed daily to environmental stressors, which cause acute damage and inflammation. Over time this leads to morphological and visual appearance changes associated with premature aging. Topical vitamin A derivatives such as retinol (ROL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d4e626e2009b6e3dea9b46557697fd0
https://doi.org/10.1101/2020.09.26.315036
https://doi.org/10.1101/2020.09.26.315036
Autor:
Frank H. Ebetino, J. Joly, Mark W. Lundy, Roy L. M. Dobson, Roslin Russell, V. A. Pavlov, A. W. Mazur
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 191:1504-1508
A new series of bisphosphonic acids bearing nitrogen containing heterocycles and carbocycles has been designed and synthesized. The most potent novel bisphosphonates were shown to have lower minera...
Autor:
Bobby Lee Barnett, Roy L. M. Dobson, Zhidao Xia, Mike Quijano, Charles E. McKenna, Roze Christian, James E. Dunford, Frank H. Ebetino, Michele Pozzi, Graham Russell, Mark Walden Lundy, Boris A. Kashemirov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5152e4e4e53dd309fa7894cd36e07208
https://doi.org/10.1016/j.bonc.2007.12.056
https://doi.org/10.1016/j.bonc.2007.12.056
Autor:
Roy L. M. Dobson, Mark W. Lundy, Adam W. Mazur, Michelle A. Lawson, Graham Russell, Xuchen Duan, Aaron Kwaasi, Hal Ebetino, Holly Evans, Julia Paton-Hough, Darren Lath, James E. Dunford, Michael Quijano, Andrew D Chantry, Gwyn Jeans, M.K. Tsoumpra, James Triffit
Publikováno v:
Bone Abstracts.
Autor:
Kevin L Harbol, Kenneth L. Morand, Kenneth D. Greis, Roy L. M. Dobson, Steven H. Hoke, Timothy R. Baker
Publikováno v:
International Journal of Mass Spectrometry. 212:135-196
In the pharmaceutical industry, there is a tremendous need for qualitative and quantitative analysis of target analytes such as peptides, proteins, drugs, metabolites, biomarkers, impurities, and degradation products in various mixtures including syn
Autor:
Timothy W. Morris, Michael C. Davis, Paul J. Renick, Shari S. Soper, A. Greg Switzer, David Robert Jones, Shyam Sunder, Christian N. Parker, Qimin Wu, Mark Edward Stella, Paul M. Hershberger, Lawrence J. Wilson, Helana D. McKeever, Gary Paul Shrum, Thomas M Burt, Kenneth L. Morand, Roy L. M. Dobson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:1149-1152
An effort to identify novel inhibitors of peptidoglycan synthesis with antibacterial activity resulted in the discovery of a series of biaryl urea-based antibacterial agents through isolation of a by-product from a mixture-based combinatorial library
Autor:
Mike Quijano, Thomas A. Neubecker, Roy L. M. Dobson, Charles A. Cruze, Mary A Coombs, Timothy P. O'Neill
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 718:225-233
A rugged, high-throughput HPLC–MS–MS-based method, suitable for quantitation of norepinephrine (NE) in urine, has been developed. A rapid, batch-mode procedure utilizes alumina to isolate NE and its deuterated internal standard from urine. After
Autor:
J. Chen, I. J. Magrisso, S. A. Green, J. M. Ridgeway, D. E. Kellstein, Lixian Gan, L. I. Wu, Debra L. Kuhlenbeck, P. A. Young, John Michael Janusz, Thomas H. Eichhold, Michael Wiard Scherz, K. Enzweiler, J. L. Tulich, Roy L. M. Dobson, T. Rosario-Jansen, Kenneth R. Wehmeyer
Publikováno v:
Journal of Medicinal Chemistry. 41:3515-3529
We report an expansion of the scope of our initial discovery that 5-keto-substituted 7-tert-butyl-2,3-dihydro-3,3-dimethylbenzofurans (DHDMBFs) are antiinflammatory and analgesic agents. Several other functional groups have been introduced at the 5 p