Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Roy Kanbar"'
Autor:
Soumana C. Nasser, Roy Kanbar, Imad F. Btaiche, Hanine Mansour, Reine Elkhoury, Carl Aoun, Lamis R. Karaoui
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background The integration of Objective Structured Clinical Examinations (OSCEs) within the professional pharmacy program, contributes to assessing the readiness of pharmacy students for Advanced Pharmacy Practice Experiences (APPEs) and rea
Externí odkaz:
https://doaj.org/article/013768113adc4aff960a547edb1e5b02
Autor:
Patrice G. Guyenet, Stephen B. G. Abbott, George M. P. R. Souza, Ruth L. Stornetta, Roy Kanbar, Daniel S. Stornetta
Publikováno v:
The Journal of Physiology. 596:2521-2545
Key points The retrotrapezoid nucleus (RTN) drives breathing proportionally to brain PCO2 but its role during various states of vigilance needs clarification. Under normoxia, RTN lesions increased the arterial PCO2 set-point, lowered the PO2 set-poin
Interdependent feedback regulation of breathing by the carotid bodies and the retrotrapezoid nucleus
Autor:
George M. P. R. Souza, Ian C. Wenker, Patrice G. Guyenet, Yingtang Shi, Tyler M. Basting, Benjamin B. Holloway, Stephen B. G. Abbott, Ruth L. Stornetta, Roy Kanbar, Douglas A. Bayliss
Publikováno v:
The Journal of Physiology. 596:3029-3042
The retrotrapezoid nucleus (RTN) regulates breathing in a CO2 - and state-dependent manner. RTN neurons are glutamatergic and innervate principally the respiratory pattern generator; they regulate multiple aspects of breathing, including active expir
Autor:
Natasha N. Kumar, Benjamin B. Holloway, Peter G R Burke, Tyler M. Basting, Patrice G. Guyenet, Roy Kanbar, Douglas A. Bayliss, Ruth L. Stornetta, Marie-Gabrielle Ludwig, Ian C. Wenker, Yingtang Shi
Publikováno v:
The Journal of Physiology. 594:1529-1551
We discuss recent evidence which suggests that the principal central respiratory chemoreceptors are located within the retrotrapezoid nucleus (RTN) and that RTN neurons are directly sensitive to [H(+) ]. RTN neurons are glutamatergic. In vitro, their
Autor:
Patrice G. Guyenet, Roy Kanbar, Ruth L. Stornetta, George M. P. R. Souza, Daniel S. Stornetta
Publikováno v:
The FASEB Journal. 32
Autor:
Tyler M. Basting, Ruth L. Stornetta, Patrice G. Guyenet, Kenneth E. Viar, Roy Kanbar, Walter M. Hodges, Peter G R Burke
Publikováno v:
The Journal of Physiology. 593:2909-2926
Key points This study explores the state dependence of the hypercapnic ventilatory reflex (HCVR). We simulated an instantaneous increase or decrease of central chemoreceptor activity by activating or inhibiting the retrotrapezoid nucleus (RTN) by opt
Autor:
Roy Kanbar, Nada Sabbah, J.J. Naoum, Hamid el Bayeh, Sonia Youhanna, Raed Othman, Marc Haber, Michella Ghassibe-Sabbagh, Samer Kibbani, Youssef G. Chami, Georges Khazen, Elie Chammas, Sally Demirdjian, Mahmoud Merhi, Pierre Zalloua, Daniel E. Platt, Antoine Abchee, Essa Hariri
Publikováno v:
Inflammation Research. 64:415-422
The role of inflammation in coronary artery disease (CAD) pathogenesis is well recognized. Moreover, smoking inhalation increases the activity of inflammatory mediators through an increase in leukotriene synthesis essential in atherosclerosis pathoge
Interdependent feedback regulation of breathing by the carotid bodies and the retrotrapezoid nucleus
Autor:
Patrice G, Guyenet, Douglas A, Bayliss, Ruth L, Stornetta, Roy, Kanbar, Yingtang, Shi, Benjamin B, Holloway, George M P R, Souza, Tyler M, Basting, Stephen B G, Abbott, Ian C, Wenker
Publikováno v:
The Journal of physiology. 596(15)
The retrotrapezoid nucleus (RTN) regulates breathing in a CO(2)‐ and state‐dependent manner. RTN neurons are glutamatergic and innervate principally the respiratory pattern generator; they regulate multiple aspects of breathing, including active
Autor:
Patrice G. Guyenet, Stephen B. G. Abbott, Ruth L. Stornetta, Melissa B. Coates, Roy Kanbar, Genrieta Bochorishvili
Publikováno v:
The Journal of Physiology. 590:2897-2915
C1 neurons activate sympathetic tone and stimulate the hypothalamic–pituitary–adrenal axis in circumstances such as pain, hypoxia or hypotension. They also innervate pontine noradrenergic cell groups, including the locus coeruleus (LC) and A5. Ac
Publikováno v:
The Journal of Physiology. 589:903-917
The ventrolateral pons contains the A5 group of noradrenergic neurons which regulate the circulation and probably breathing. The present experiments were designed to identify these neurons definitively in vivo, to examine their response to chemorecep